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Grup A Streptokok Ve İnfluenza A / B'nin Sebep Olduğu Üst Solunum Yolu Enfeksiyonlarının Karşılaştırması

Year 2020, Volume: 77 Issue: 4, 477 - 486, 01.12.2020

Abstract

Amaç: İnfluenza koenfeksiyonu şeklinde olan bakteriyel enfeksiyonlar özellikle yaşlılar ve küçük çocuklar gibi yüksek riskli gruplar arasında ciddi bir morbidite ve mortalite nedenidir. Çalışmamızda olgularımızda saptanan grup A streptokok ile influenza virüs tip A ve tip B nedenli üst solunum yolu enfeksiyonlarının klinik ve laboratuvar bulgularının karşılaştırılması ile her iki etkenin koenfeksiyon sıklığının irdelenmesi amaçlanmıştır. Yöntem: Çalışmaya üçüncü basamak hastanemiz pediatri kliniğine üst solunum yolu enfeksiyonları şikayetiyle 2019 Ocak - 2020 Ocak tarihleri arasında başvuran ve streptokok hızlı antijen testi ile influenza A ve B hızlı testleri uygulanan toplam 1884 çocuk hasta dahil edildi. Eş zamanlı olarak çocukların tam kan sayımı ve C-reaktif protein testleri de çalışılmış olup sonuçlar influenza virüsü ve grup A steptokok enfeksiyonları için karşılaştırıldı. Sonuçların istatistiksel analizi yapıldı ve p

References

  • 1. Bisno AL. Primary care: Acute pharyngitis. N Engl J Med, 2001; 344: 205-11.
  • 2. Brennan-Krohn T, Ozonoff A, Sandora TJ. Adherence to guidelines for testing and treatment of children with pharyngitis: a retrospective study. BMC Pediatr, 2018; 18: 43-50.
  • 3. Tünger Ö. Akut tonsillofarenjitler. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 2015; 2:2-7.
  • 4. Peteranderl C, Herold S, Schmoldt C. Human Influenza Virus Infections. Semin Respir Crit Care Med, 2016; 37: 487-500.
  • 5. Labella AM, Merel SE. Influenza. Med Clin North Am, 2013; 97: 621-45.
  • 6. Kondrich J, Rosenthal M. Influenza in children. Curr Opin Pediatr, 2017; 29: 297-302.
  • 7. Kumar V. Influenza in Children. Indian J Pediatr, 2017; 84: 139-43.
  • 8. Öngen B. A Grubu Streptokok İnfeksiyonlarında Tanı. ANKEM Derg, 2004; 18: 45-50.
  • 9. Ji MJ, Noh JS, Cho BK, Cho YS, Kim SJ, Yoon BS. Evaluation of SD BIOLINE Chagas Ab rapid kit. Korean J Lab Med, 2009; 29: 48-52.
  • 10. Maltezou HC, Tsagrid V, Antoniadou A, Galani L, Douros C, Katsarolis I, et al. Evaluation of a rapid antigen detection test in the diagnosis of streptococcal pharyngitis in children and its impact on antibiotic prescription. J Antimicrob Chemother, 2008; 62: 1407-12.
  • 11. Cohen JF, Bertille N, Cohen R, Chalumeau M. Rapid antigen detection test for group A streptococcus in children with pharyngitis. Cochrane Database Syst Rev 2016; 7: CD010502.
  • 12. Cohen J F, Chalumeau M, Levy C, Bidet P, Thollot F, Wollner A, et al. Spectrum and inoculum size effect of a rapid antigen detection test for group A streptococcus in children with pharyngitis. PLoS One, 2012; 7: e39085.
  • 13. Gurol Y, Romano E, Coskun FT, Biçer S, Çelik G. Group A streptococcal infection cases during influenza season 2016 Coinfections in influenza season. Egyptian Pediatric Association Gazette, 2017; 65(2); 31-32.
  • 14. Joseph C, Togawa Y, Shindo N. Bacterial and viral infections associated with influenza Influenza Other Respir Viruses, 2013; (2): 105-113.
  • 15. Ruiz-Aragón J, Rodríguez López R, Molina Linde JM. Evaluation of rapid methods for detecting Streptococcus pyogenes. Systematic review and meta-analysis. An Pediatr (Barc), 2010; 72: 391- 402.
  • 16. Cabbarpur C, Özlüoğlu LN, Çakmak Ö, Büyüklü F, Haşimoğlu R, Ergin F, et al. Akut Tonsillofarenjitte Rapid Strep A Testi Kullanımı. Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, 2004; 3: 10-2.
  • 17. Lamagni TL, Darenberg J, Luca-Harari B, Siljander T, Efstratiou A, Henriques-Normark B, et al. Epidemiology of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol, 2008; 46(7): 2359-67.
  • 18. Scaber J, Saeed S, Ihekweazu C, A Efstratio, McCarth N, O’Moore E. Group A streptococcal infections during the seasonal influenza outbreak 2010/11 in South East England. Euro Surveill, 2011;16(5), 19780.
  • 19. Jean C, Louie JK, Glaser CA, Harriman K, Hacker JK, Aranki F, et al. Invasive group A streptococcal infection concurrent with 2009 H1N1 influenza. Clin Infect Dis, 2010; 50(10): e59-62.
  • 21. Saygılı N, Bulut E, Deniz R, Dalgıç N, Aktaş E. Boğaz Sürüntü Örneklerinde A Grubu Beta-Hemolitik Streptokokların Belirlenmesinde Bionexia Strep A Plus Hızlı Antijen Testinin Kullanımı. Türk Mikrobiyol Cem Derg, 2017; 47: 138-45.
  • 22. Van Brusselen D, Vlieghe E, Schelstraete P, De Meulder F, Vandeputte C, Garmyn K, et al. Streptococcal pharyngitis in children: to treat or not to treat? Eur J Pediatr, 2014; 173: 1275-83.
  • 23. Cohen JF, Cohen R, Bidet P, Levy C, Deberdt P, d’Humières C, et al. Rapid-antigen detection tests for group a streptococcal pharyngitis: revisiting false-positive results using polymerase chain reaction testing. J Pediatr 2013; 162: 1282-4.
  • 24. Bulut ME, Aktaş E, Malkoçoğlu G, Yavuz Özer V, Ünal B, Bayraktar B. Strep A Hızlı Antijen Testiyle Grup A Streptokokların Belirlenmesinde İkili Sürüntü Çubuğu Kullanımı Bir Gereklilik mi? Türk Mikrobiyoloji Cem Derg 2019; 49: 30-4.
  • 25. Çoban B, Kaplan H, Topal B, Ülkü N. The sensitivity and the specifity of rapid antigen test in Group A streptococcal tonsillopharyngitis. J Pediatr Inf , 2013; 7: 143-6.
  • 26. Barış A, Anlıaçık N, Bulut ME, Deniz R, Yücel E, Aktaş E. A Grubu Beta-hemolitik streptokok farenjiti tanısında Mascia Brunelli hızlı antijen testinin değerlendirilmesi. Mikrobiyol Bul, 2017; 51: 73-8.
  • 27. Gözüküçük R, Göçmen İ, Nas Y, Yılmazer F, Ünüvar E. Streptokoksik tonsillofarenjit tanısında strep-A hızlı testinin etkinliği. Çocuk Dergisi, 2011; 11: 157-9.
  • 28. Altundağ Altun H, Meral T, Türk Arıbaş E. The specificity and sensitivity results of the rapid antigen test used in the diagnosis of group a beta hemolytic Streptococcal tonsillopharyngitis. Acta Medica Mediterr, 2015; 31: 287-90.
  • 29. Önal A, Aslan S, Bozkaya E, Badur S. Türkiye’de 2003-2004 ve 2004-2005 yıllarında grip sürveyansı ve izole edilen influenza virus suşlarının tiplendirimi. Klimik Dergisi, 2006; 19: 3-9.
  • 30. Küçük Ö, Biçer S, Giray T, Çöl D, Çiler Erdağ G, Uğraş M, et al. Evaluation of the Patients with Influenza Viruses. J Pediatr Inf, 2013; 7: 87-91.
  • 31. Gültekingil A. 2017-2018 Mevsimsel İnfluenza Salgını Klinik Özellikleri: Tek Merkez Deneyimi. J Pediatr Emerg Intensive Care Med 2018; 5: 119-23.
  • 32. Cohen JF, Cohen R, Levy C, Thollot F, Benani M, Bidet P, et al. Selective testing strategies for diagnosing group A streptococcal infection in children with pharyngitis: a systematic review and prospective multicentre external validation study. CMAJ, 2015; 187: 23-32.
  • 33. Gonsu HK, Bomki CM, Djomou F, Toukam M, Ndze VN, Lyonga EE, et al. A comparative study of the diagnostic methods for Group A Streptococcal Sore Throat in Two Reference Hospitals In Yaounde, Cameroon. Pan Afr Med J, 2015; 20: 139.
  • 34. Gerber AM, Baltimore RS, Eaton BC, Gewitz M, Rowley AH, Shulman ST, et al. Prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis: A scientific statement from the american haert association rheumatic fever, endocarditis, and kawasaki disease committee of the council on cardiovascular disaese in the young, the interdisciplinary council on functional genomics and translational biology, and theinterdisciplinary councik on quality of care and outcomes research: Endorsed by the american academy of pediatrics. Circ, 2009; 191: 1541-51.

A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B

Year 2020, Volume: 77 Issue: 4, 477 - 486, 01.12.2020

Abstract

Objective: Coinfections of influenza virus with bacterial infections are an important cause of morbidity and mortality, especially among high-risk groups like young children and the elderly. This study aimed at the comparison between clinical and laboratory findings of upper respiratory tract infections caused by group A streptococcus and influenza virus type A and B to determine the frequency of coinfection.Methods: A total of 1884 patients who applied to the pediatrics clinic of our tertiary referral hospital with complaints of upper respiratory tract infections between January 2019 and January 2020 which were performed the antigen group a streptococcus and influenza A and B rapid tests were included to our study. Complete blood counts and C-reactive protein tests were compared in between the patients with influenza virus and group A streptococcus. Values of

References

  • 1. Bisno AL. Primary care: Acute pharyngitis. N Engl J Med, 2001; 344: 205-11.
  • 2. Brennan-Krohn T, Ozonoff A, Sandora TJ. Adherence to guidelines for testing and treatment of children with pharyngitis: a retrospective study. BMC Pediatr, 2018; 18: 43-50.
  • 3. Tünger Ö. Akut tonsillofarenjitler. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 2015; 2:2-7.
  • 4. Peteranderl C, Herold S, Schmoldt C. Human Influenza Virus Infections. Semin Respir Crit Care Med, 2016; 37: 487-500.
  • 5. Labella AM, Merel SE. Influenza. Med Clin North Am, 2013; 97: 621-45.
  • 6. Kondrich J, Rosenthal M. Influenza in children. Curr Opin Pediatr, 2017; 29: 297-302.
  • 7. Kumar V. Influenza in Children. Indian J Pediatr, 2017; 84: 139-43.
  • 8. Öngen B. A Grubu Streptokok İnfeksiyonlarında Tanı. ANKEM Derg, 2004; 18: 45-50.
  • 9. Ji MJ, Noh JS, Cho BK, Cho YS, Kim SJ, Yoon BS. Evaluation of SD BIOLINE Chagas Ab rapid kit. Korean J Lab Med, 2009; 29: 48-52.
  • 10. Maltezou HC, Tsagrid V, Antoniadou A, Galani L, Douros C, Katsarolis I, et al. Evaluation of a rapid antigen detection test in the diagnosis of streptococcal pharyngitis in children and its impact on antibiotic prescription. J Antimicrob Chemother, 2008; 62: 1407-12.
  • 11. Cohen JF, Bertille N, Cohen R, Chalumeau M. Rapid antigen detection test for group A streptococcus in children with pharyngitis. Cochrane Database Syst Rev 2016; 7: CD010502.
  • 12. Cohen J F, Chalumeau M, Levy C, Bidet P, Thollot F, Wollner A, et al. Spectrum and inoculum size effect of a rapid antigen detection test for group A streptococcus in children with pharyngitis. PLoS One, 2012; 7: e39085.
  • 13. Gurol Y, Romano E, Coskun FT, Biçer S, Çelik G. Group A streptococcal infection cases during influenza season 2016 Coinfections in influenza season. Egyptian Pediatric Association Gazette, 2017; 65(2); 31-32.
  • 14. Joseph C, Togawa Y, Shindo N. Bacterial and viral infections associated with influenza Influenza Other Respir Viruses, 2013; (2): 105-113.
  • 15. Ruiz-Aragón J, Rodríguez López R, Molina Linde JM. Evaluation of rapid methods for detecting Streptococcus pyogenes. Systematic review and meta-analysis. An Pediatr (Barc), 2010; 72: 391- 402.
  • 16. Cabbarpur C, Özlüoğlu LN, Çakmak Ö, Büyüklü F, Haşimoğlu R, Ergin F, et al. Akut Tonsillofarenjitte Rapid Strep A Testi Kullanımı. Kulak Burun Boğaz ve Baş Boyun Cerrahisi Dergisi, 2004; 3: 10-2.
  • 17. Lamagni TL, Darenberg J, Luca-Harari B, Siljander T, Efstratiou A, Henriques-Normark B, et al. Epidemiology of severe Streptococcus pyogenes disease in Europe. J Clin Microbiol, 2008; 46(7): 2359-67.
  • 18. Scaber J, Saeed S, Ihekweazu C, A Efstratio, McCarth N, O’Moore E. Group A streptococcal infections during the seasonal influenza outbreak 2010/11 in South East England. Euro Surveill, 2011;16(5), 19780.
  • 19. Jean C, Louie JK, Glaser CA, Harriman K, Hacker JK, Aranki F, et al. Invasive group A streptococcal infection concurrent with 2009 H1N1 influenza. Clin Infect Dis, 2010; 50(10): e59-62.
  • 21. Saygılı N, Bulut E, Deniz R, Dalgıç N, Aktaş E. Boğaz Sürüntü Örneklerinde A Grubu Beta-Hemolitik Streptokokların Belirlenmesinde Bionexia Strep A Plus Hızlı Antijen Testinin Kullanımı. Türk Mikrobiyol Cem Derg, 2017; 47: 138-45.
  • 22. Van Brusselen D, Vlieghe E, Schelstraete P, De Meulder F, Vandeputte C, Garmyn K, et al. Streptococcal pharyngitis in children: to treat or not to treat? Eur J Pediatr, 2014; 173: 1275-83.
  • 23. Cohen JF, Cohen R, Bidet P, Levy C, Deberdt P, d’Humières C, et al. Rapid-antigen detection tests for group a streptococcal pharyngitis: revisiting false-positive results using polymerase chain reaction testing. J Pediatr 2013; 162: 1282-4.
  • 24. Bulut ME, Aktaş E, Malkoçoğlu G, Yavuz Özer V, Ünal B, Bayraktar B. Strep A Hızlı Antijen Testiyle Grup A Streptokokların Belirlenmesinde İkili Sürüntü Çubuğu Kullanımı Bir Gereklilik mi? Türk Mikrobiyoloji Cem Derg 2019; 49: 30-4.
  • 25. Çoban B, Kaplan H, Topal B, Ülkü N. The sensitivity and the specifity of rapid antigen test in Group A streptococcal tonsillopharyngitis. J Pediatr Inf , 2013; 7: 143-6.
  • 26. Barış A, Anlıaçık N, Bulut ME, Deniz R, Yücel E, Aktaş E. A Grubu Beta-hemolitik streptokok farenjiti tanısında Mascia Brunelli hızlı antijen testinin değerlendirilmesi. Mikrobiyol Bul, 2017; 51: 73-8.
  • 27. Gözüküçük R, Göçmen İ, Nas Y, Yılmazer F, Ünüvar E. Streptokoksik tonsillofarenjit tanısında strep-A hızlı testinin etkinliği. Çocuk Dergisi, 2011; 11: 157-9.
  • 28. Altundağ Altun H, Meral T, Türk Arıbaş E. The specificity and sensitivity results of the rapid antigen test used in the diagnosis of group a beta hemolytic Streptococcal tonsillopharyngitis. Acta Medica Mediterr, 2015; 31: 287-90.
  • 29. Önal A, Aslan S, Bozkaya E, Badur S. Türkiye’de 2003-2004 ve 2004-2005 yıllarında grip sürveyansı ve izole edilen influenza virus suşlarının tiplendirimi. Klimik Dergisi, 2006; 19: 3-9.
  • 30. Küçük Ö, Biçer S, Giray T, Çöl D, Çiler Erdağ G, Uğraş M, et al. Evaluation of the Patients with Influenza Viruses. J Pediatr Inf, 2013; 7: 87-91.
  • 31. Gültekingil A. 2017-2018 Mevsimsel İnfluenza Salgını Klinik Özellikleri: Tek Merkez Deneyimi. J Pediatr Emerg Intensive Care Med 2018; 5: 119-23.
  • 32. Cohen JF, Cohen R, Levy C, Thollot F, Benani M, Bidet P, et al. Selective testing strategies for diagnosing group A streptococcal infection in children with pharyngitis: a systematic review and prospective multicentre external validation study. CMAJ, 2015; 187: 23-32.
  • 33. Gonsu HK, Bomki CM, Djomou F, Toukam M, Ndze VN, Lyonga EE, et al. A comparative study of the diagnostic methods for Group A Streptococcal Sore Throat in Two Reference Hospitals In Yaounde, Cameroon. Pan Afr Med J, 2015; 20: 139.
  • 34. Gerber AM, Baltimore RS, Eaton BC, Gewitz M, Rowley AH, Shulman ST, et al. Prevention of rheumatic fever and diagnosis and treatment of acute streptococcal pharyngitis: A scientific statement from the american haert association rheumatic fever, endocarditis, and kawasaki disease committee of the council on cardiovascular disaese in the young, the interdisciplinary council on functional genomics and translational biology, and theinterdisciplinary councik on quality of care and outcomes research: Endorsed by the american academy of pediatrics. Circ, 2009; 191: 1541-51.
There are 33 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Hayrettin Temel This is me

Mehmet Gündüz This is me

Publication Date December 1, 2020
Published in Issue Year 2020 Volume: 77 Issue: 4

Cite

APA Temel, H., & Gündüz, M. (2020). A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B. Türk Hijyen Ve Deneysel Biyoloji Dergisi, 77(4), 477-486.
AMA Temel H, Gündüz M. A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B. Turk Hij Den Biyol Derg. December 2020;77(4):477-486.
Chicago Temel, Hayrettin, and Mehmet Gündüz. “A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B”. Türk Hijyen Ve Deneysel Biyoloji Dergisi 77, no. 4 (December 2020): 477-86.
EndNote Temel H, Gündüz M (December 1, 2020) A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B. Türk Hijyen ve Deneysel Biyoloji Dergisi 77 4 477–486.
IEEE H. Temel and M. Gündüz, “A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B”, Turk Hij Den Biyol Derg, vol. 77, no. 4, pp. 477–486, 2020.
ISNAD Temel, Hayrettin - Gündüz, Mehmet. “A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B”. Türk Hijyen ve Deneysel Biyoloji Dergisi 77/4 (December 2020), 477-486.
JAMA Temel H, Gündüz M. A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B. Turk Hij Den Biyol Derg. 2020;77:477–486.
MLA Temel, Hayrettin and Mehmet Gündüz. “A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B”. Türk Hijyen Ve Deneysel Biyoloji Dergisi, vol. 77, no. 4, 2020, pp. 477-86.
Vancouver Temel H, Gündüz M. A Comparison Of Upper Respiratory Tract İnfections Caused By Group A Streptococci And İnfluenza A/B. Turk Hij Den Biyol Derg. 2020;77(4):477-86.