The Comparison of Selection Criteria and Results for Incisional and Excisional Biopsy in Breast Masses

Year 2023, , 380 - 385, 30.06.2023

Bülent Halaçlar , Feray Aydın , Özgür Albuz

https://doi.org/10.18663/tjcl.1313710

Abstract

The main purpose of this study is to clarify the biopsy selection criteria by revealing the biopsy methods and post-biopsy surgical treatment choices and pathology results in cases with biopsy indication.
Material and Methods:The study was carried out in cases who applied to the General Surgery Clinic between June 2020 and June 2022 and had biopsy indication.In fact;The records of 62 patients aged 18-70 years who were diagnosed with benign or malignant masses after excisional biopsy, tru-cut or incisional biopsy were retrospectively reviewed, and cases with incomplete or uncertain data were not included in the study.Descriptive statistics are given as mean±standard deviation, percentage and frequency.Student t test was used for continuous variables in the comparison of binary groups, χ2 test was used for comparison of binary variables, and the p<0.05 value in the 95% confidence interval was considered statistically significant.
Results:The total number of cases was 62.The mean age of the patients included in the study was 41.11±14.74.On the other hand, the mean age of the cases diagnosed as malignant after biopsy was found to be higher than the benign cases[(49.46±15.38)vs(39.31±14.10)(p<0.05)].The number of cases with BI-RADS 4 was found to be significantly higher in the group who underwent trucut or incisional biopsy[(n=11(91.6%)].Biopsy incidences;n=12(19.4%) incisional or trucut biopsies were performed, and the remaining 50(80.6%) cases underwent excisional biopsy.It was seen that patients who underwent incisional or trucut procedure were statistically significantly malignant [n=11(91.6%) vs 1(8.4%)(p<0.05)].According to the total number of patients, the results of malignancy in cases who underwent incisional or trucut biopsy were significantly higher than those who underwent excisional biopsy[n=11(17.7%)vs51(82.3%)(p<0.0001)].
Conclusion:We think that the cases diagnosed with breast cancer generally have masses that are not palpable as a result of mammography examinations performed in the preoperative period, and therefore, the cases with excisional biopsy are usually benign, and preoperative imaging is very important like physical examination.

Keywords

Excisional biopsy, incisional biopsy, breast, mass, biopsy selection

Supporting Institution

Herhangibir destekleyen kurum veya kuruluş yoktur

Project Number

Etik kurul onay numarası: 130

Meme Kitlelerinde Eksizyonel ve İnsizyonel Biyopsi İşlemlerinin Seçim Kriterleri ve Sonuçları

Abstract

Amaç: Bu çalışmanın temel amacı, biopsi endikasyonu görülen olgularda biopsi yöntemlerini ve biopsi sonrası cerrahi tedavi seçimleriyle patoloji sonuçlarını ortaya koyarak biopsi seçim kriterlerini netleştirmektir.
Gereç ve Yöntemler: Çalışma haziran 2020 ve haziran 2022 tarihleri arasında Genel Cerrahi Kliniğine başvuran ve biopsi endikasyonu konulan olgularda gerçekleştirildi. Esas olarak; Eksizyonel biopsi, tru-cut veya insizyonel biyopsi sonrası benign veya malign kitle tanıları konulan 18-70 yaş arası 62 hasta kayıtları retrospektif olerek incelemeye alınmış olup, verileri eksik ya da belirsiz olan olgular çalışmaya dahil edilmemiştir. Bu tanımlayıcı istatistikler ortalama±standart sapma, yüzde ve frekans olarak verilmiştir. İkili grupların karşılaştırılmasında sürekli değişkenler için bağımsız gruplarta student t test, ikili değişkenlerin karşılaştırılmasında χ2 testi kullanılmış ve %95 güven aralığındaki p<0,05 değeri istatistiksel olarak anlamlı kabul edilmiş olup nihai sonuçlara regresyon analizi yapılarak ulaşılmıştır.
Bulgular: Toplam olgu sayısı 62 idi. Çalışmaya alınan hastaların yaş ortalaması 41,11±14,74 idi. Diğer yandan biopsi sonrası malignite tanısı alan olguların yaş ortalaması, benign olgulura göre daha yüksek saptandı[(49,46±15,38) vs (39,31±14,10) (p<0.05)].BI-RADS 4 gelen olgu sayısı trucut veye iniszyonel biopisi yapılan grupta belirgin biçimde yüksek olarak bulundu[(n=11(91.6%)].
Biopsi insidansları; n= 12(19.4%) insizyonel veya trucut biopsisi yapılmış olup, geri kalan 50 (80.6%) olguya eksizyonel biopsi yapılmıştır.İnsizyonel veya trucut işlemi uygulanan hastaların istatistiki olarak anlamlı biçimde malign geldiği görülmüştür [n=11( %91.6) vs 1(8.4%)(p<0.05)].Toplam hasta sayısına göre de insizyonel veya trucut biopsi yapılan olguların malignite ile sonuçlanmaları eksizyonel biopsi yapılan olgulara göre anlamlı olarak yüksektir[ n=11(17.7%)vs 51(82.3%) (p<0.0001)].
Sonuç: Meme kanseri tanısı konan olguların genel olarak preoperatif dönemde yapılan mammografi tetkikleri neticesinde ele gelmeyen kitleler olduğu ve bu sebeple eksizyonel biopisi yapılan olguların belirgin olarak benigin geldiğini ,preoperatif görüntülemenin, fizik muayane gibi çok önemli olduğunu düşünüyoruz.

Keywords

Eksizyonel biyopsi, insizyonel biyopsi, meme, kitle, biyopsi seçimi

Project Number

Etik kurul onay numarası: 130

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