Short course of conventional dose oral prednisone therapy in immune thrombocytopenic purpura associated with parvovirus B19 infection

Abstract

Childhood immune thrombocytopenic purpura (ITP) is usually benign and a self-limited disorder. Often there is a preceding viral like illness or vaccination. Human parvovirus B-19 (HPV) has also been detected in blood or bone marrow samples of some patients with acute ITP. Treatment of ITP due to HPV is controversial. We report a case presented with macroscopic hematuria and diagnosed as acute ITP due to HPV, and treated with short course conventional dose oral prednisone successfully. This treatment seems to be safe and effective and may be an alternative treatment option to IVIG therapy in patients with HPV associated with ITP

Keywords

• Immune thrombocytopenic purpura,parvovirus B19,prednisone

Parvovirüs B19 enfeksiyonunda görülen immün trombositopenik purpurada kısa süreli konvansiyonel doz oral prednizon tedavisi

Abstract

Çocukluk çağı immün trombositopenik purpura (İTP) genellikle benign ve kendini sınırlayan bir hastalıktır. Genellikle viral bir hastalık ya da aşılama sonrası oluşur. Akut ITP olan bazı hastaların kan veya kemik iliği örneklerinde İnsan parvovirüs B-19 (HPV) tespit edilmiştir. HPV nedeniyle İTP tedavisi tartışmalıdır. Bu yazıda makroskopik hematüri ve HPV’ye bağlı akut İTP tanılı olgunun kısa süreli konvansiyonel doz oral prednizon ile başarılı tedavisini sunduk. Güvenli ve etkili olan bu tedavi, HPV ilişkili İTP hastalarında İVİG tedavisine alternatif bir seçenek olabilir.

Keywords

• İmmun trombositopenik purpura,parvovirus B19,prednison

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