Nutrisyonel boy kısalığı olan adolesanlarda nutrisyonel destek tedavisinin büyüme faktörleri üzerine etkisi: uzun süreli izlem sonuçları

Abstract

Amaç: Uzun süreli yetersiz nutrisyon alımı çocukluk çağında boy kazanımını negatif olarak etkiler.  Bu çalışmanın amacı nutrisyonel boy kısalığı (NBK) tanısı alan adolesanlarda oral nutrisyonel destek ürününün (ONDÜ) büyüme hızı (BH) ve büyüme faktörleri (BF) üzerine olan etkisini incelemektir.

Gereç ve Yöntemler: NBK tanısı alan 16 adolesan çalışmaya dahil edildi. Hastalar oral beslenme ile alımlarını kaydetti, kalori açıkları hesaplandı ve açıkları ONDÜ ile tamamlandı. Nutrisyonel destek tedavisinin BH, BF ve büyüme parametreleri üzerine etkisi 0, 6, 12. aylarda değerlendirildi.

Bulgular: Olguların 6. ve 12. aylardaki boy kazanımları; 6. aydaki IGF-BP3 artışı; 12. aydaki IGF-1, beden kitle indeksi ve vücut ağırlığı SDS artışı istatistiksel olarak anlanlı saptandı. (p<0.05).

Sonuç: Nutrisyonel boy kısalığı olan adolesanlara verilen uzun sureli ONDÜ tedavisi büyüme faktörlerini arttırmaktadır. IGF-1 seviyesindeki artış güvenli sınırlar içerisinde saptanmıştır. 

Keywords

• Nutrisyon tedavisi,boy kısalığı,adolesan

The effect of nutritional support treatment on growth factors in adolescents with nutritional short stature: result of long-term follow-up

Abstract

Aim: Long-term insufficient nutrition intake in childhood affects height gain negatively. This study was designed to analyze the effect of oral nutritional support product (ONSP) treatment on growth velocity (GV) and growth factors (GF) in adolescents who diagnosed as nutritional short stature (NSS).

Material and Methods: Sixteen adolescents diagnosed as NSS were involved. Patients recorded their dietary intake; caloric deficiencies were calculated and fulfilled with ONSP. Effect of nutritional support treatment on GV, GF and growth parameters were analyzed on 0^th, 6^th ,12^th   months.

Results: The increment of the height of the cases on 6^th and 12^th month, increment of IGFBP3 on 6^th month, the increment of IGF-1 levels, BMI and weight SDS of the cases on 12^th month and  were statistically significant (p < 0.05).

Conclusions: Long-term ONSP treatment, which is given to the adolescents with NSS increases the growth factors. The increment of IGF-1 levels was in between secure limits.

Keywords

• Nutrition therapy,short stature,adolescents

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