Cardiovascular effects of thiopental-sevoflurane compared with thiopental-isoflurane in angora goats undergoing ovariectomy

Abstract

Aim: The purpose of this study was to evaluate the effects of inhalation anaesthetics on cardiovascular functions in 16 healthy female Angora goats undergoing ovariectomy. Material and Methods: Anaesthesia was induced with thiopental sodium then maintained with isoflurane or sevoflurane in oxygen. Cardiovascular parameters were measured before and at 0, 15th, 30th, 60th and 90th minutes after induction of anaesthesia.  Recovery variables including time to extubation, first lift of the head, thoracic recumbency and standing up were also recorded.

Results: The mean induction dose of thiopental was 18.23 ± 3.87 mg / kg. There were no significant differences between groups for heart rate (HR), respiration rate (RR), noninvasive blood pressure and body temperature measured prior to and under anaesthesia. All animals recovered uneventfully in both groups.

Conclusion: There were no statistical differences between groups for their cardiovascular parameters and recovery times although the results of this study showed a rapid recovery time in each parameter for sevoflurane anaesthesia. On the basis of the results, sevoflurane and isoflurane are suitable inhalation anaesthetics in goats. 

Keywords

• anaesthesia,sevoflurane,isoflurane,angora goat,cardiovascular

Ankara keçilerinde ovariektomi operasyonlarında tiopental-sevofluran ile tiopental-isofluran’ın kardiyovasküler sistem üzerine etkilerinin karşılaştırılması

Abstract

Amaç: Bu çalışmada 16 adet sağlıklı Ankara keçisinin ovarektomi operasyonlarında kullanılan inhalasyon anesteziklerinin kardiyovasküler sistem üzerine etkilerinin değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntemler: Anestezinin indüksiyonu tiopental sodyum ile yapılmış ve devamında izofluran ve sevofluran inhalasyon anestezikleri kullanılmıştır. Kardiyovasküler değerler indüksiyondan önce ve indüksiyon sonrası 0. 15. 30. 60 ve 90. dakikalarda kayıt edilmiştir. Ekstubasyon ve kafayı ilk kaldırma zamanı, sternal pozisyona gelme ve ayağa kalkma zamanları uyanma kriterlerini oluşturmuştur.

Bulgular: Tiopental sodyumun ortalama indüksiyon dozu 18.23±3.87 mg/kg olarak belirlenmiştir. Gruplar arasında, anestezi sırasında ve anesteziden önce nabız sayısı, solunum sayısı, noninvaziv tansiyon değerleri ve vücut ısısında farklılık gözlenmemiştir. Tüm hayvanların anesteziden uyanmaları sorunsuz bir şekilde gerçekleşmiştir. 

Sonuç: Çalışmanın sonucunda kullanılan anesteziklerin uyanma zamanları ve kardiyovasküler değerler üzerine etkileri arasında istatistiksel olarak farklılık olmadığı tespit edilmiştir. Sevofluran anestezisinde tüm uyanma kriterlerinin daha hızlı şekillendiği görülmüştür. Sonuç olarak her iki anestezik maddeninde keçilerin inhalasyon anestezisinde kullanımının uygun olduğu kanısına varılmıştır. 

Keywords

• Anestezi,Ankara keçisi,Isofluran,Kardiyovasküler

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