Cardiovascular effects of thiopental-sevoflurane compared with thiopental-isoflurane in angora goats undergoing ovariectomy

Year 2019, , 42 - 46, 21.03.2019

Birkan Karslı , İlknur Pir Yağcı , Zeynep Pekcan , Ali Kumandaş Hakan Kalender

https://doi.org/10.18663/tjcl.406243

Abstract

Aim:
The purpose of
this study was to evaluate the effects of inhalation anaesthetics on
cardiovascular functions in 16 healthy female Angora goats undergoing
ovariectomy. Material and Methods: Anaesthesia
was induced with thiopental sodium then maintained with isoflurane or
sevoflurane in oxygen. Cardiovascular parameters were measured before and at 0,
15th, 30th, 60th and 90th minutes after induction of anaesthesia.  Recovery variables including time to
extubation, first lift of the head, thoracic recumbency and standing up were
also recorded.

Results: The mean induction dose of thiopental was 18.23 ± 3.87
mg / kg. There were no significant differences between groups for heart rate
(HR), respiration rate (RR), noninvasive blood pressure and body temperature measured
prior to and under anaesthesia. All animals recovered uneventfully in both
groups.

Conclusion: There were no statistical
differences between groups for their cardiovascular parameters and recovery
times although the results of this study showed a rapid recovery time in each
parameter for sevoflurane anaesthesia. On the basis of the results, sevoflurane
and isoflurane are suitable inhalation anaesthetics in goats. 

Keywords

anaesthesia, sevoflurane, isoflurane, angora goat, cardiovascular

Ankara keçilerinde ovariektomi operasyonlarında tiopental-sevofluran ile tiopental-isofluran’ın kardiyovasküler sistem üzerine etkilerinin karşılaştırılması

Abstract

Amaç:
Bu çalışmada 16 adet sağlıklı Ankara keçisinin
ovarektomi operasyonlarında kullanılan inhalasyon anesteziklerinin
kardiyovasküler sistem üzerine etkilerinin değerlendirilmesi amaçlanmıştır.

Gereç
ve Yöntemler: Anestezinin
indüksiyonu tiopental sodyum ile yapılmış ve devamında izofluran ve sevofluran
inhalasyon anestezikleri kullanılmıştır. Kardiyovasküler değerler indüksiyondan
önce ve indüksiyon sonrası 0. 15. 30. 60 ve 90. dakikalarda kayıt edilmiştir. Ekstubasyon
ve kafayı ilk kaldırma zamanı, sternal pozisyona gelme ve ayağa kalkma
zamanları uyanma kriterlerini oluşturmuştur.

Bulgular: Tiopental sodyumun ortalama indüksiyon dozu 18.23±3.87 mg/kg
olarak belirlenmiştir. Gruplar arasında, anestezi sırasında ve anesteziden önce nabız
sayısı, solunum sayısı, noninvaziv tansiyon değerleri ve vücut ısısında
farklılık gözlenmemiştir. Tüm hayvanların anesteziden uyanmaları sorunsuz bir
şekilde gerçekleşmiştir. 

Sonuç:
Çalışmanın sonucunda kullanılan anesteziklerin
uyanma zamanları ve kardiyovasküler değerler üzerine etkileri arasında
istatistiksel olarak farklılık olmadığı tespit edilmiştir. Sevofluran
anestezisinde tüm uyanma kriterlerinin daha hızlı şekillendiği görülmüştür.
Sonuç olarak her iki anestezik maddeninde keçilerin inhalasyon anestezisinde
kullanımının uygun olduğu kanısına varılmıştır. 

Keywords

Anestezi, Ankara keçisi, Isofluran, Kardiyovasküler

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