Seçkin atletlerde tam kan viskozitesi ve sol ventrikül geometrisi: atlet kalbi üzerine bir çalışma

Year 2019, , 136 - 141, 12.06.2019

Serkan Duyuler

https://doi.org/10.18663/tjcl.520967

Abstract

Amaç: Bu çalışmada, bir grup seçkin
sporcudaki tam kan viskozitesi ile sol ventriküler yeniden şekillenme arasında
olası ilişki değerlendirilmiştir.

Gereç ve Yöntemler: Bu çalışma seçkin atletlerin (65
futbolcu, 12 basketbolcu) katılımı ile gerçekleştirildi. Sol ventrikül kütlesi,
transtorasik ekokardiyografi ile hesaplandı. Tam kan viskozitesinin
hesaplanması hematokriti ve toplam plazma protein konsantrasyonunu kullanan
formüller aracılığıyla hem yüksek kesme hızı (HSR= 208/s) hem de düşük kesme
hızında (LSR= 0.5/s) gerçekleştirildi. Sol ventrikül kütle indeksi 115 g/m2
üzeri olması sol ventrikül hipertrofisi olarak tanımlandı, Katılımcıların tam
kan viskoziteleri ve klinik özellikleri sol ventrikül hipertrofisi olup
olmamasına göre karşılaştırıldı.

Bulgular: Çalışmaya katılan 24 sporcuda sol ventrikül
hipertrofisi mevcut idi. Tam kan viskozitesi hem yüksek kesme hızında (sol
ventrikül hipertrofisi olmayan grup için HSR tam kan viskozitesi=17,4±0,89 cP
karşın hipertrofi olan grup HSR tam kan viskozitesi= 17,95±0,78 cP; p= 0,011),
hem de düşük kesme hızında (sol ventrikül hipertrofisi olmayan grup  için HSR tam kan viskozitesi=63,7±18,9 cP
karşın hipertrofi olan grup LSR tam kan viskozitesi= 76,36±16,35 cP; p=0,006)
sol ventrikül hipertrofisi  olan sporcu
grubunda anlamlı şekilde daha yüksekti. Çoklu değişkenli lojistik regresyon
analizinde tam kan viskozitesi düşük ve yüksek kesme değerleri için ayrı ayrı
ayrı modellere alındı. Tam kan viskozitesi hem düşük kesme hızında (OR=1,057,
%95 CI: 1,017-1,098; p=0,005), hem de yüksek kesme hızında (OR=2,885, %95 CI:
1,319-6,313; p=0,008) sol ventrikül hipertrofisi ile ilişki bulundu.

Sonuç: Seçkin
sporcularda gözlenen sol ventrikül hipertrofisinde tam kan viskozitesinin
muhtemel bir rolü olabilir.

Keywords

sporcu, sol ventrikül hipertrofisi, kan viskozitesi

Whole blood viscosity and left ventricle geometry in elite athletes: a study on athlete's heart

Abstract

Aim: In this study, the relationship between whole blood
viscosity and left ventricular remodeling in a group of elite athletes was
evaluated.

Material and Methods: This study was carried out with the
participation of elite athletes (65 footballers, 12 basketball players). Left
ventricular mass was calculated by transthoracic echocardiography. The calculation
of the whole blood viscosity was performed by using both the high shear rate
(HSR = 208/s) and the lower shear rate (LSR = 0.5/s) through the formulas using
hematocrit and total plasma protein concentration. Left ventricular mass index
above 115 g/m2 was defined as left ventricular hypertrophy. The whole blood
viscosities and clinical features of the participants were compared according
to the presence of left ventricular hypertrophy.

Results: Left ventricular hypertrophy was
present in 24 athletes.Left ventricular hypertrophy was present in 24 athletes.
Whole blood viscosity at both high shear rate (HSR whole blood viscosity for
the group without left ventricular hypertrophy = 17.4 ± 0.89 cP, vs  HSR whole blood viscosity for the group with
hypertrophy= 17.95 ± 0.78 cP; p = 0.011), LSR whole blood viscosity for group
without left ventricular hypertrophy = 63.7 ± 18.9 cP vs  LSR whole blood viscosity for the group  with hypertrophy = 76.36 ± 16.35 cP; p =
0.006) left ventricular hypertrophy was significantly higher in the group of
athletes. In multivariate logistic regression analysis, whole blood viscosity
was taken to separate models for low and high shear rates. Whole blood
viscosity at the low shear rate (OR=1.057, 95%
CI: 1.017-1.098; p=0.005), as well as at the high shear rate (OR=2.885, 95% CI: 1.319-6.313; p=0.008)
was significantly associated with left ventricular hypertrophy.

Conclusion: Whole blood viscosity may have a
possible role in left ventricular hypertrophy observed in elite athletes. 

Keywords

athlete, left ventricular hypertrophy, blood viscosity

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