Anti-adhesion activity and physicochemical features of the surgical silk sutures coated with Liquidambar orientalis styrax

Abstract

Aim: The present study was aimed to characterize the surgical silk sutures coated with Styrax liquidus, Turkish sweetgum balsam obtained from Liquidambar orientalis, and to investigate their anti-adhesion capacity against oral pathogenic microorganisms.
Material and Methods: Fourier Transform Infrared Spectroscopy (FTIR) was applied to determine the chemical composition of the Liquidambar orientalis styrax (LOS)-coated sutures. Thermogravimetric Analysis (TGA) was performed to compare the thermal stability of the LOS-coated sutures. Scanning Electron Microscopy (SEM) was used to evaluate the morphological structure of the sutures. Anti-adhesion activity of the LOS-coated sutures was investigated against common oral pathogenic microorganisms.
Results: FTIR spectrum and SEM images revealed out that LOS was succesfully coated onto the silk sutures. TGA analysis showed that LOS coating moderately affected the thermal stability of the silk sutures. According to the anti-adhesion activity analysis, the highest activity was observed against S. aureus, a gram positive bacteria.
Conclusion: Coating the surgical silk sutures with LOS might be useful to prevent the surgical site infections in oral surgery.

Keywords

• anti-adhesion
• characterization
• Liquidambar orientalis
• styrax
• suture

Liquidambar orientalis styrax ile kaplanan cerrahi ipek sütürlerin anti-adezyon aktivitesi ve fizikokimyasal özellikleri

Abstract

Amaç: Bu çalışmada, Liquidambar orientalis'ten elde edilen Türk sığla balsamı olan Styrax liquidus ile kaplanmış cerrahi ipek sütürlerin karakterize edilmesi ve oral patojenik mikroorganizmalara karşı anti-adezyon kapasitelerinin araştırılması amaçlandı.
Gereç ve Yöntemler: Liquidambar orientalis styrax (LOS) kaplı sütürlerin kimyasal bileşimini belirlemek için Fourier Transform Kızılötesi Spektroskopisi (FTIR) uygulandı. LOS kaplı sütürlerin termal stabilitesini karşılaştırmak için Termogravimetrik Analiz (TGA) yapıldı. Sütürlerin morfolojik yapısını değerlendirmek için Taramalı Elektron Mikroskopisi (SEM) kullanıldı. LOS kaplı sütürlerin anti-adezyon aktivitesi, yaygın oral patojenik mikroorganizmalara karşı araştırıldı.
Bulgular: FTIR spektrumu ve SEM görüntüleri LOS'un ipek sütürlere başarılı bir şekilde kaplandığını ortaya koydu. TGA analizi, LOS kaplamanın ipek sütürlerin termal stabilitesini orta derecede etkilediğini gösterdi. Anti-adezyon aktivite analizine göre, en yüksek aktivitenin gram pozitif bakteri olan S. aureus'a karşı olduğu gözlendi.
Sonuç: Cerrahi ipek sütürlerin LOS ile kaplanması, oral cerrahide cerrahi bölge enfeksiyonlarını önlemek için yararlı olabilmektedir.

Keywords

• anti-adezyon
• karakterizasyon
• Liquidambar orientalis
• styrax
• sütür

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