The temporal changes in mean platelet volume after bariatric surgery

Year 2024, Volume: 15 Issue: 3, 481 - 487, 30.09.2024

Sabiha Kömoğlu , Aziz Bora Karip , Yasin Güneş , Nalan Okuroğlu , Ali Özdemir

https://doi.org/10.18663/tjcl.1545635

Abstract

Aim: Studies on obese individuals have proposed a correlation between weight loss and variations in mean platelet volume (MPV). Therefore, this study aimed to examine the changes in MPV in morbidly obese patients who underwent weight loss via bariatric surgery.
Material and Methods: A total of 328 morbidly obese patients who underwent sleeve gastrectomy (morbidly obese group) and were retrospectively evaluated from January 2010 to November 2014. The control group consisted of 53 non-obese patients who had laparoscopic cholecystectomy. Body mass index values and MPV values at preoperative (baseline), postoperative 1st month, 3rd month, and 12th month for both groups were documented.
Results: The baseline MPV values were comparable between morbidly obese group and control group (8.8 ± 1.8 vs. 8.6 ± 1.2, p = 0.283). In control group, there was no significant change in MPV levels during the 12-month follow-up. In morbidly obese group, mean MPV levels at the 1st and 3rd months post-surgery were similar, showing an increase compared to baseline levels. By the 12th month, mean MPV levels tended to decrease, becoming comparable to baseline values.
Conclusion: MPV levels increased in the early postoperative period following sleeve gastrectomy, they returned to baseline by the 12th month. These findings suggest that weight loss from bariatric surgery may influence MPV levels, but this effect normalizes over time.

Keywords

bariatric surgery, sleeve gastrectomy, mean platelet volume, obesity

Bariatrik cerrahi sonrası ortalama trombosit hacmindeki zamansal değişiklikler

Abstract

Amaç: Obez bireyler üzerinde yapılan çalışmalar, kilo kaybı ile ortalama trombosit hacmi (MPV) değişiklikleri arasında bir ilişki olduğunu öne sürmüştür. Bu nedenle, bu çalışma, bariatrik cerrahi ile kilo kaybı yaşayan morbid obez hastalarda MPV'deki değişiklikleri incelemeyi amaçladı.
Gereç ve Yöntemler: Ocak 2010 ile Kasım 2014 tarihleri arasında sleeve gastrektomi yapılan toplam 328 morbid obez hasta (morbid obez grup) retrospektif olarak değerlendirildi. Kontrol grubu, laparoskopik kolesistektomi geçiren 53 obez olmayan hastadan oluştu. Her iki grup için preoperative (bazal), postoperatif 1. ay, 3. ay ve 12. ayda vücut kitle indeksi ve MPV değerleri kaydedildi.
Bulgular: Bazal MPV değerleri, morbid obez grubu ile kontrol grubu arasında benzerdi (8.8 ± 1.8 vs. 8.6 ± 1.2, p = 0.283). Kontrol grubunda, 12 aylık takip süresince MPV seviyelerinde anlamlı bir değişiklik gözlenmedi. Morbid obez grubunda, cerrahi sonrası 1. ve 3. ayda ortalama MPV seviyeleri benzer olup, bazal seviyelere göre artış gösterdi. 12. ayda ise ortalama MPV seviyeleri azalma eğilimi göstererek, bazal değerlere benzer hale geldi.
Sonuçlar: MPV seviyeleri, sleeve gastrektomi sonrası erken postoperatif dönemde artış gösterdi, ancak 12. ayda başlangıç seviyelerine döndü. Bu bulgular, bariatrik cerrahi ile kilo kaybının MPV seviyelerini etkileyebileceğini, ancak bu etkinin zamanla normale döndüğünü göstermektedir.

Keywords

bariatrik cerrahi, sleeve gastrektomi, ortalama trombosit hacmi, obezite

Ethical Statement

The study was performed in accordance with the Declaration of Helsinki, and was approved by the Fatih Sultan Mehmet Training and Research Hospital Clinical Research Ethics Committee (Date: 27.10.2014, Decision No: 2014/9).

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