Ground Glass Appearance During the Pandemic Period: Everolimus Induced Interstitial Pneumonia

Year 2022, , 126 - 129, 01.04.2022

Sidelya Ecem Yiğit , İffet Beril Gökmen , Yıldız Okuturlar

https://doi.org/10.46310/tjim.1078775

Abstract

Ground glass appearance is a nonspecific finding that can see in diseases such as chronic interstitial disease, acute alveolar disease or infection; however, it is most commonly encountered in COVID-19 pulmonary involvement today. The mammalian target of rapamycin (mTOR) plays a regulatory role in cell proliferation and growth. Everolimus is an allosteric mTOR inhibitor used in ER+ breast cancers and inhibits the mTOR functional complex. Here, we present a case of interstitial pneumonia due to everolimus, which can be confused with COVID-19 pneumonia due to its ground-glass appearance during the pandemic period.

Keywords

Everolimus, mTOR, ground glass, interstitial pneumonia, Covid-19, breast cancer

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