Case Report
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Year 2021, , 92 - 93, 07.03.2021
https://doi.org/10.46310/tjim.882244

Abstract

References

  • Reference1. Bilezikian JP, Khan A, Potts JT Jr, et al. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011;26(10):2317-2337. doi:10.1002/jbmr.483
  • Reference2. Shoback D. Clinical practice. Hypoparathyroidism. N Engl J Med. 2008;359(4):391-403. doi:10.1056/NEJMcp0803050
  • Reference3. Russell CF, Edis AJ. Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role of surgery in the asymptomatic patient. Br J Surg. 1982;69(5):244-247. doi:10.1002/bjs.1800690503
  • Reference4. Winer KK, Yanovski JA, Cutler GB Jr. Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA. 1996;276(8):631-636.
  • Reference5. Gafni RI, Collins MT. Hypoparathyroidism. N Engl J Med. 2019;380(18):1738-1747. doi:10.1056/NEJMcp1800213
  • Reference6. Gafni RI, Langman CB, Guthrie LC, et al. Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. J Bone Miner Res. 2018;33(10):1741-1747. doi:10.1002/jbmr.3480
  • Reference7. Goujard C, Salenave S, Briot K, Chanson P, Grimon G, Kamenický P. Treating hypoparathyroidism with recombinant human parathyroid hormone (1-34): long-term safety concerns. Lancet. 2020;395(10232):1304. doi:10.1016/S0140-6736(20)30538-9

A Case of Resistant Hypocalcemia Treated with Teriparatide

Year 2021, , 92 - 93, 07.03.2021
https://doi.org/10.46310/tjim.882244

Abstract

Postsurgical chronic hypoparathyroidism is most commonly seen in adults. Synthetic recombinant human parathyroid hormone (rhPTH) 1-34 can be used to stabilize serum calcium levels in patients with resistant hypocalcemia in rare conditions.
Here we report a 52-year-old woman with postsurgical uncontrolled hypocalcemia despite the usual therapy. Once-daily treatment with PTH 1-34 maintained serum calcium within the normal range and reduced the dose of previous medical therapies.

References

  • Reference1. Bilezikian JP, Khan A, Potts JT Jr, et al. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011;26(10):2317-2337. doi:10.1002/jbmr.483
  • Reference2. Shoback D. Clinical practice. Hypoparathyroidism. N Engl J Med. 2008;359(4):391-403. doi:10.1056/NEJMcp0803050
  • Reference3. Russell CF, Edis AJ. Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role of surgery in the asymptomatic patient. Br J Surg. 1982;69(5):244-247. doi:10.1002/bjs.1800690503
  • Reference4. Winer KK, Yanovski JA, Cutler GB Jr. Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA. 1996;276(8):631-636.
  • Reference5. Gafni RI, Collins MT. Hypoparathyroidism. N Engl J Med. 2019;380(18):1738-1747. doi:10.1056/NEJMcp1800213
  • Reference6. Gafni RI, Langman CB, Guthrie LC, et al. Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. J Bone Miner Res. 2018;33(10):1741-1747. doi:10.1002/jbmr.3480
  • Reference7. Goujard C, Salenave S, Briot K, Chanson P, Grimon G, Kamenický P. Treating hypoparathyroidism with recombinant human parathyroid hormone (1-34): long-term safety concerns. Lancet. 2020;395(10232):1304. doi:10.1016/S0140-6736(20)30538-9
There are 7 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Ensar Aydemir 0000-0001-8519-784X

Canan Ersoy 0000-0003-4510-6282

Özen Öz Gül 0000-0002-1332-4165

Soner Cander 0000-0001-6303-7896

Yasemin Aydoğan Ünsal 0000-0002-1566-3099

Coşkun Ateş 0000-0003-4565-9848

Erdinç Ertürk 0000-0003-2399-6608

Publication Date March 7, 2021
Submission Date February 18, 2021
Acceptance Date March 6, 2021
Published in Issue Year 2021

Cite

EndNote Aydemir E, Ersoy C, Öz Gül Ö, Cander S, Aydoğan Ünsal Y, Ateş C, Ertürk E (March 1, 2021) A Case of Resistant Hypocalcemia Treated with Teriparatide. Turkish Journal of Internal Medicine 3 Supplement 1 92–93.

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