Case Report
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Year 2021, Volume: 3 Issue: Supplement 1, 92 - 93, 07.03.2021

Ensar Aydemir , Canan Ersoy , Özen Öz Gül , Soner Cander , Yasemin Aydoğan Ünsal , Coşkun Ateş , Erdinç Ertürk

https://doi.org/10.46310/tjim.882244
https://izlik.org/JA37XW67KN

Abstract

References

  • Reference1. Bilezikian JP, Khan A, Potts JT Jr, et al. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011;26(10):2317-2337. doi:10.1002/jbmr.483
  • Reference2. Shoback D. Clinical practice. Hypoparathyroidism. N Engl J Med. 2008;359(4):391-403. doi:10.1056/NEJMcp0803050
  • Reference3. Russell CF, Edis AJ. Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role of surgery in the asymptomatic patient. Br J Surg. 1982;69(5):244-247. doi:10.1002/bjs.1800690503
  • Reference4. Winer KK, Yanovski JA, Cutler GB Jr. Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA. 1996;276(8):631-636.
  • Reference5. Gafni RI, Collins MT. Hypoparathyroidism. N Engl J Med. 2019;380(18):1738-1747. doi:10.1056/NEJMcp1800213
  • Reference6. Gafni RI, Langman CB, Guthrie LC, et al. Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. J Bone Miner Res. 2018;33(10):1741-1747. doi:10.1002/jbmr.3480
  • Reference7. Goujard C, Salenave S, Briot K, Chanson P, Grimon G, Kamenický P. Treating hypoparathyroidism with recombinant human parathyroid hormone (1-34): long-term safety concerns. Lancet. 2020;395(10232):1304. doi:10.1016/S0140-6736(20)30538-9

A Case of Resistant Hypocalcemia Treated with Teriparatide

Year 2021, Volume: 3 Issue: Supplement 1, 92 - 93, 07.03.2021

Ensar Aydemir , Canan Ersoy , Özen Öz Gül , Soner Cander , Yasemin Aydoğan Ünsal , Coşkun Ateş , Erdinç Ertürk

https://doi.org/10.46310/tjim.882244
https://izlik.org/JA37XW67KN

Abstract

Postsurgical chronic hypoparathyroidism is most commonly seen in adults. Synthetic recombinant human parathyroid hormone (rhPTH) 1-34 can be used to stabilize serum calcium levels in patients with resistant hypocalcemia in rare conditions.
Here we report a 52-year-old woman with postsurgical uncontrolled hypocalcemia despite the usual therapy. Once-daily treatment with PTH 1-34 maintained serum calcium within the normal range and reduced the dose of previous medical therapies.

Keywords

Hypoparathyroidism Hypocalcemia Teriparatide

References

  • Reference1. Bilezikian JP, Khan A, Potts JT Jr, et al. Hypoparathyroidism in the adult: epidemiology, diagnosis, pathophysiology, target-organ involvement, treatment, and challenges for future research. J Bone Miner Res. 2011;26(10):2317-2337. doi:10.1002/jbmr.483
  • Reference2. Shoback D. Clinical practice. Hypoparathyroidism. N Engl J Med. 2008;359(4):391-403. doi:10.1056/NEJMcp0803050
  • Reference3. Russell CF, Edis AJ. Surgery for primary hyperparathyroidism: experience with 500 consecutive cases and evaluation of the role of surgery in the asymptomatic patient. Br J Surg. 1982;69(5):244-247. doi:10.1002/bjs.1800690503
  • Reference4. Winer KK, Yanovski JA, Cutler GB Jr. Synthetic human parathyroid hormone 1-34 vs calcitriol and calcium in the treatment of hypoparathyroidism. JAMA. 1996;276(8):631-636.
  • Reference5. Gafni RI, Collins MT. Hypoparathyroidism. N Engl J Med. 2019;380(18):1738-1747. doi:10.1056/NEJMcp1800213
  • Reference6. Gafni RI, Langman CB, Guthrie LC, et al. Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. J Bone Miner Res. 2018;33(10):1741-1747. doi:10.1002/jbmr.3480
  • Reference7. Goujard C, Salenave S, Briot K, Chanson P, Grimon G, Kamenický P. Treating hypoparathyroidism with recombinant human parathyroid hormone (1-34): long-term safety concerns. Lancet. 2020;395(10232):1304. doi:10.1016/S0140-6736(20)30538-9
There are 7 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Report
Authors

Ensar Aydemir 0000-0001-8519-784X

Canan Ersoy 0000-0003-4510-6282

Özen Öz Gül 0000-0002-1332-4165

Soner Cander 0000-0001-6303-7896

Yasemin Aydoğan Ünsal 0000-0002-1566-3099

Coşkun Ateş 0000-0003-4565-9848

Erdinç Ertürk 0000-0003-2399-6608

Submission Date February 18, 2021
Acceptance Date March 6, 2021
Publication Date March 7, 2021
DOI https://doi.org/10.46310/tjim.882244
IZ https://izlik.org/JA37XW67KN
Published in Issue Year 2021 Volume: 3 Issue: Supplement 1

Cite

APA Aydemir, E., Ersoy, C., Öz Gül, Ö., Cander, S., Aydoğan Ünsal, Y., Ateş, C., & Ertürk, E. (2021). A Case of Resistant Hypocalcemia Treated with Teriparatide. Turkish Journal of Internal Medicine, 3(Supplement 1), 92-93. https://doi.org/10.46310/tjim.882244
AMA 1.Aydemir E, Ersoy C, Öz Gül Ö, et al. A Case of Resistant Hypocalcemia Treated with Teriparatide. Turk J Int Med. 2021;3(Supplement 1):92-93. doi:10.46310/tjim.882244
Chicago Aydemir, Ensar, Canan Ersoy, Özen Öz Gül, et al. 2021. “A Case of Resistant Hypocalcemia Treated With Teriparatide”. Turkish Journal of Internal Medicine 3 (Supplement 1): 92-93. https://doi.org/10.46310/tjim.882244.
EndNote Aydemir E, Ersoy C, Öz Gül Ö, Cander S, Aydoğan Ünsal Y, Ateş C, Ertürk E (March 1, 2021) A Case of Resistant Hypocalcemia Treated with Teriparatide. Turkish Journal of Internal Medicine 3 Supplement 1 92–93.
IEEE [1]E. Aydemir et al., “A Case of Resistant Hypocalcemia Treated with Teriparatide”, Turk J Int Med, vol. 3, no. Supplement 1, pp. 92–93, Mar. 2021, doi: 10.46310/tjim.882244.
ISNAD Aydemir, Ensar - Ersoy, Canan - Öz Gül, Özen - Cander, Soner - Aydoğan Ünsal, Yasemin - Ateş, Coşkun - Ertürk, Erdinç. “A Case of Resistant Hypocalcemia Treated With Teriparatide”. Turkish Journal of Internal Medicine 3/Supplement 1 (March 1, 2021): 92-93. https://doi.org/10.46310/tjim.882244.
JAMA 1.Aydemir E, Ersoy C, Öz Gül Ö, Cander S, Aydoğan Ünsal Y, Ateş C, Ertürk E. A Case of Resistant Hypocalcemia Treated with Teriparatide. Turk J Int Med. 2021;3:92–93.
MLA Aydemir, Ensar, et al. “A Case of Resistant Hypocalcemia Treated With Teriparatide”. Turkish Journal of Internal Medicine, vol. 3, no. Supplement 1, Mar. 2021, pp. 92-93, doi:10.46310/tjim.882244.
Vancouver 1.Ensar Aydemir, Canan Ersoy, Özen Öz Gül, Soner Cander, Yasemin Aydoğan Ünsal, Coşkun Ateş, Erdinç Ertürk. A Case of Resistant Hypocalcemia Treated with Teriparatide. Turk J Int Med. 2021 Mar. 1;3(Supplement 1):92-3. doi:10.46310/tjim.882244

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