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A Case of very Severe Hypertriglyceridemia during Pregnancy

Year 2021, , 94 - 95, 07.03.2021
https://doi.org/10.46310/tjim.882279

Abstract

Severe hypertriglyceridemia is defined as serum triglyceride levels of 1000 mg/dL and more. Acute pancreatitis and fetal losses can be observed in association with severely high triglyceride levels during pregnancy.
Here we report the management of a 28-year-old pregnant woman with very severe HTG with the data in the literature.

References

  • Berglund L, Brunzell JD, Goldberg AC, et al. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline [published correction appears in J Clin Endocrinol Metab. 2015 Dec;100(12):4685]. J Clin Endocrinol Metab. 2012;97(9):2969-2989. doi:10.1210/jc.2011-3213
  • Fan W, Philip S, Granowitz C, Toth PP, Wong ND. Hypertriglyceridemia in statin-treated US adults: the National Health and Nutrition Examination Survey. J Clin Lipidol. 2019;13(1):100-108. doi:10.1016/j.jacl.2018.11.008
  • Scherer J, Singh VP, Pitchumoni CS, Yadav D. Issues in hypertriglyceridemic pancreatitis: an update. J Clin Gastroenterol. 2014;48(3):195-203. doi:10.1097/01.mcg.0000436438.60145.5a
  • Ghio A, Bertolotto A, Resi V, Volpe L, Di Cianni G. Triglyceride metabolism in pregnancy. Adv Clin Chem. 2011;55:133-153. doi:10.1016/b978-0-12-387042-1.00007-1
  • Saadi HF, Kurlander DJ, Erkins JM, Hoogwerf BJ. Severe hypertriglyceridemia and acute pancreatitis during pregnancy: treatment with gemfibrozil. Endocr Pract. 1999;5(1):33-36. doi:10.4158/EP.5.1.33
  • Zhu Y, Pan X, Zeng H, et al. A Study on the Etiology, Severity, and Mortality of 3260 Patients With Acute Pancreatitis According to the Revised Atlanta Classification in Jiangxi, China Over an 8-Year Period. Pancreas. 2017;46(4):504-509. doi:10.1097/MPA.0000000000000776
  • Kleess LE, Janicic N. SEVERE HYPERTRIGLYCERIDEMIA IN PREGNANCY: A CASE REPORT AND REVIEW OF THE LITERATURE. AACE Clin Case Rep. 2018;5(2):e99-e103. Published 2018 Oct 5. doi:10.4158/ACCR-2018-0168
  • Alyse S. Goldberg, Robert A. Hegele, Severe Hypertriglyceridemia in Pregnancy, The Journal of Clinical Endocrinology & Metabolism, Volume 97, Issue 8, 1 August 2012, Pages 2589–2596, https://doi.org/10.1210/jc.2012-1250
  • Newman CB, Blaha MJ, Boord JB, et al. Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2020;105(12):dgaa674. doi:10.1210/clinem/dgaa674
Year 2021, , 94 - 95, 07.03.2021
https://doi.org/10.46310/tjim.882279

Abstract

References

  • Berglund L, Brunzell JD, Goldberg AC, et al. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline [published correction appears in J Clin Endocrinol Metab. 2015 Dec;100(12):4685]. J Clin Endocrinol Metab. 2012;97(9):2969-2989. doi:10.1210/jc.2011-3213
  • Fan W, Philip S, Granowitz C, Toth PP, Wong ND. Hypertriglyceridemia in statin-treated US adults: the National Health and Nutrition Examination Survey. J Clin Lipidol. 2019;13(1):100-108. doi:10.1016/j.jacl.2018.11.008
  • Scherer J, Singh VP, Pitchumoni CS, Yadav D. Issues in hypertriglyceridemic pancreatitis: an update. J Clin Gastroenterol. 2014;48(3):195-203. doi:10.1097/01.mcg.0000436438.60145.5a
  • Ghio A, Bertolotto A, Resi V, Volpe L, Di Cianni G. Triglyceride metabolism in pregnancy. Adv Clin Chem. 2011;55:133-153. doi:10.1016/b978-0-12-387042-1.00007-1
  • Saadi HF, Kurlander DJ, Erkins JM, Hoogwerf BJ. Severe hypertriglyceridemia and acute pancreatitis during pregnancy: treatment with gemfibrozil. Endocr Pract. 1999;5(1):33-36. doi:10.4158/EP.5.1.33
  • Zhu Y, Pan X, Zeng H, et al. A Study on the Etiology, Severity, and Mortality of 3260 Patients With Acute Pancreatitis According to the Revised Atlanta Classification in Jiangxi, China Over an 8-Year Period. Pancreas. 2017;46(4):504-509. doi:10.1097/MPA.0000000000000776
  • Kleess LE, Janicic N. SEVERE HYPERTRIGLYCERIDEMIA IN PREGNANCY: A CASE REPORT AND REVIEW OF THE LITERATURE. AACE Clin Case Rep. 2018;5(2):e99-e103. Published 2018 Oct 5. doi:10.4158/ACCR-2018-0168
  • Alyse S. Goldberg, Robert A. Hegele, Severe Hypertriglyceridemia in Pregnancy, The Journal of Clinical Endocrinology & Metabolism, Volume 97, Issue 8, 1 August 2012, Pages 2589–2596, https://doi.org/10.1210/jc.2012-1250
  • Newman CB, Blaha MJ, Boord JB, et al. Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2020;105(12):dgaa674. doi:10.1210/clinem/dgaa674
There are 9 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Ensar Aydemir 0000-0001-8519-784X

Satı Burcu Çetin 0000-0003-3760-6017

Yasemin Aydoğan Ünsal 0000-0002-1566-3099

Coşkun Ateş 0000-0003-4565-9848

Soner Cander 0000-0001-6303-7896

Özen Öz Gül 0000-0002-1332-4165

Erdinç Ertürk 0000-0003-2399-6608

Canan Ersoy 0000-0003-4510-6282

Publication Date March 7, 2021
Submission Date February 18, 2021
Acceptance Date March 6, 2021
Published in Issue Year 2021

Cite

EndNote Aydemir E, Çetin SB, Aydoğan Ünsal Y, Ateş C, Cander S, Öz Gül Ö, Ertürk E, Ersoy C (March 1, 2021) A Case of very Severe Hypertriglyceridemia during Pregnancy. Turkish Journal of Internal Medicine 3 Supplement 1 94–95.

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