Aim: This study investigated the effect of mycophenolate mofetil (MPA) treatment instead of azathioprine (AZA) on renal function after kidney transplantation.
Methods: Thirteen of all recipients were taking a cyclosporine-based regimen and serum creatinine levels were above 1.5 mg/dL. In 13 patients, MPA treatment was started instead of AZA. Renal functions were evaluated for 12 months after MPA treatment.
Results: Serum creatinine levels increased from 2.11±0.48 mg/dL to 2.16±0.72 mg/dL at 12th months. This increase was not statistically significant. Serum creatinine levels decreased in 5 of 13 patients.
Conclusion: In selected patients, conversion from AZA to MPA may slow down the rate of deterioration in graft functions.
|Journal Section||Original Articles|
|Supporting Institution||ULUDAG UNIVERSITY|
|Publication Date||October 29, 2019|
|Application Date||October 11, 2019|
|Acceptance Date||October 22, 2019|
|Published in Issue||Year 2019, Volume 1, Issue 1|
|EndNote||%0 Turkish Journal of Internal Medicine Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients %A Mehmet Usta , Alparslan Ersoy , Yavuz Ayar %T Effect of conversion from azathioprine to mycophenolate mofetil on renal function in stable kidney transplant recipients %D 2019 %J Turkish Journal of Internal Medicine %P -2687-4245 %V 1 %N 1 %R doi: 10.46310/tjim.632066 %U 10.46310/tjim.632066|