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Large ganglioneuroma case mimicking as an adrenal adenoma

Year 2021, Volume: 3 Issue: Supplement 1, 123 - 126, 07.03.2021
https://doi.org/10.46310/tjim.877025

Abstract

Ganglioneuroma (GN) is a rarely seen benign tumor originating from neural crest cells and consisting of ganglion and Schwann cells. Adrenal GNs occur most frequently in the fourth and fifth decades of life. They have an equal frequency in male and female patients and are usually found incidentally during imaging. It is not related to hormonal activity and is clinically asymptomatic. We aimed to present a 49-year-old female patient whose magnetic resonance image performed for abdominal pain was found a biochemically normal mass in the right adrenal gland and then was pathologically diagnosed as GN after right adrenalectomy.

References

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  • 2. Allende DS, Hansel DE, MacLennan GT. Ganglioneuroma of the Adrenal Gland. J Urol 2009;182(2):714–5.
  • 3. Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001;91(10):1905–13.
  • 4. Mylonas KS, Schizas D, Economopoulos KP. Adrenal ganglioneuroma: What you need to know. World J Clin Cases 2017;5(10):373–7.
  • 5. Qing Y, Bin X, Jian W, et al. Adrenal ganglioneuromas: a 10-year experience in a Chinese population. Surgery 2010;147(6):854–60.
  • 6. Shier KJ, Shaalan AK, Horn RC. Malignant Ganglioneuroma: Report of A Case of an Aggressively Growing Immature Ganglioneuroma. Can Med Assoc J 1961;85(3):135–9.
  • 7. Inci I, Turgut M. Neurogenic tumors of the mediastinum in children. Childs Nerv Syst ChNS Off J Int Soc Pediatr Neurosurg 1999;15(8):372–6.
  • 8. Mendelsohn G, Eggleston JC, Olson JL, Said SI, Baylin SB. Vasoactive intestinal peptide and its relationship to ganglion cell differentiation in neuroblastic tumors. Lab Investig J Tech Methods Pathol 1979;41(2):144–9.
  • 9. Fassnacht M, Arlt W, Bancos I, et al. Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 2016;175(2):G1–34.
  • 10. Sasaki S, Yasuda T, Kaneto H, et al. Large adrenal ganglioneuroma. Intern Med Tokyo Jpn 2012;51(17):2365–70.
Year 2021, Volume: 3 Issue: Supplement 1, 123 - 126, 07.03.2021
https://doi.org/10.46310/tjim.877025

Abstract

References

  • 1. Joshi VV. Peripheral neuroblastic tumors: pathologic classification based on recommendations of international neuroblastoma pathology committee (Modification of shimada classification). Pediatr Dev Pathol Off J Soc Pediatr Pathol Paediatr Pathol Soc 2000;3(2):184–99.
  • 2. Allende DS, Hansel DE, MacLennan GT. Ganglioneuroma of the Adrenal Gland. J Urol 2009;182(2):714–5.
  • 3. Geoerger B, Hero B, Harms D, Grebe J, Scheidhauer K, Berthold F. Metabolic activity and clinical features of primary ganglioneuromas. Cancer 2001;91(10):1905–13.
  • 4. Mylonas KS, Schizas D, Economopoulos KP. Adrenal ganglioneuroma: What you need to know. World J Clin Cases 2017;5(10):373–7.
  • 5. Qing Y, Bin X, Jian W, et al. Adrenal ganglioneuromas: a 10-year experience in a Chinese population. Surgery 2010;147(6):854–60.
  • 6. Shier KJ, Shaalan AK, Horn RC. Malignant Ganglioneuroma: Report of A Case of an Aggressively Growing Immature Ganglioneuroma. Can Med Assoc J 1961;85(3):135–9.
  • 7. Inci I, Turgut M. Neurogenic tumors of the mediastinum in children. Childs Nerv Syst ChNS Off J Int Soc Pediatr Neurosurg 1999;15(8):372–6.
  • 8. Mendelsohn G, Eggleston JC, Olson JL, Said SI, Baylin SB. Vasoactive intestinal peptide and its relationship to ganglion cell differentiation in neuroblastic tumors. Lab Investig J Tech Methods Pathol 1979;41(2):144–9.
  • 9. Fassnacht M, Arlt W, Bancos I, et al. Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. Eur J Endocrinol 2016;175(2):G1–34.
  • 10. Sasaki S, Yasuda T, Kaneto H, et al. Large adrenal ganglioneuroma. Intern Med Tokyo Jpn 2012;51(17):2365–70.
There are 10 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Murat Çalapkulu 0000-0002-7445-2275

Muhammed Erkam Sencar 0000-0001-5581-4886

İlknur Öztürk Ünsal 0000-0003-3999-6426

Hakan Düğer 0000-0001-5478-3192

Mustafa Özbek 0000-0003-1125-3823

Erman Çakal 0000-0003-4455-7276

Publication Date March 7, 2021
Submission Date February 8, 2021
Acceptance Date March 7, 2021
Published in Issue Year 2021 Volume: 3 Issue: Supplement 1

Cite

EndNote Çalapkulu M, Sencar ME, Öztürk Ünsal İ, Düğer H, Özbek M, Çakal E (March 1, 2021) Large ganglioneuroma case mimicking as an adrenal adenoma. Turkish Journal of Internal Medicine 3 Supplement 1 123–126.

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