Thyrotoxic Hypokalemic Periodic Paralysis: A Case Report

Year 2022, Volume: 4 - Supplement 1, 169 - 171, 01.04.2022

Şeyma Esenbuğa , Ensar Aydemir , Canan Ersoy

https://doi.org/10.46310/tjim.1072023

Abstract

Thyrotoxic hypokalemic periodic paralysis is a rare and fatal complication of hyperthyroidism and is associated with low serum potassium levels and muscle weakness. Herein, we presented a young male patient who did not use the antithyroid drugs given for Graves’ disease and was admitted with the complaint of weakness in the extremities and diagnosed with thyrotoxic hypokalemic periodic paralysis.

Keywords

Thyrotoxicosis, hypokalemia, paralysis

References

• Nazir M, Hameed M, Shehzad R. Thyrotoxic hypokalemic periodic paralysis: A success story of a diagnostic challenge. Cureus. 2021 Apr 19;13(4):e14553. doi: 10.7759/cureus.14553.
• Siddamreddy S, Dandu VH. Thyrotoxic periodic paralysis. 2021 Jul 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–.
• Ryan DP, da Silva MR, Soong TW, Fontaine B, Donaldson MR, Kung AW, Jongjaroenprasert W, Liang MC, Khoo DH, Cheah JS, Ho SC, Bernstein HS, Maciel RM, Brown RH Jr, Ptácek LJ. Mutations in potassium channel Kir2.6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis. Cell. 2010 Jan 8;140(1):88-98. doi: 10.1016/j.cell.2009.12.024.
• Verma V, Kumar Y, Kotwal N, Upreti V, Hari Kumar KVS, Singh Y, Menon AS. Thyrotoxic periodic paralysis: A retrospective, observational study from India. Indian J Med Res. 2020 Jan;151(1):42-46. doi: 10.4103/ijmr.IJMR_335_18.
• Jackson I, Addasi Y, Ahmed M, Ramadan B, Kalian K, Addasi N, Nayfeh A, Taylor J, Bashir K, Krajicek B. Hypokalemic periodic paralysis precipitated by thyrotoxicosis and renal tubular acidosis. Case Rep Endocrinol. 2021 Jun 21;2021:4529009. doi: 10.1155/2021/4529009.
• Falhammar H, Thorén M, Calissendorff J. Thyrotoxic periodic paralysis: clinical and molecular aspects. Endocrine. 2013 Apr;43(2):274-84. doi: 10.1007/s12020-012-9777-x.