Purpose:Hypothalamic pituitary adrenal (HPA) axis has many missions such as responses to stress and inflammatory factors. HPA axis is the primer stress response system. Adropin is a peptid structured hormone coded by energy homeostasis related gene. In this study biochemical, histopathologic and immunohistochemical effects of adropin hormone on HPA axis were examined.
Findings:While cortisole, adrenaline, noradrenaline and serotonin levels decreased, contrary dopamin levels increased. There were no important changes on melatonin levels. As a consequence of immunohistochemical staining, CRH has shown increase in adropin groups compared to other groups.
Department of Scientific Research Projects of Atatürk University
2016/64
2016/64
Primary Language | English |
---|---|
Journal Section | Volume IV, Issue II, 2019 |
Authors | |
Project Number | 2016/64 |
Publication Date | October 28, 2019 |
Published in Issue | Year 2019 Volume: 4 Issue: 2 |