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Year 2019, Volume: 3 Issue: 1, 13 - 20, 30.04.2019

Abstract

References

  • Abdel-Moneim A, El-Feki M, Salah E. Effect of Nigella sativa, fish oil and gliclazide on alloxan diabetic rats 1-biochemical and histopathological studies. J Egy Ger Soci Zool 1997; 23:237-266.
  • Augsteen AA, Abu-Umair MS, Mahmoud SA. Biochemical analysis of serum pancreatic amylase and lipase enzymes in patients with type 1 and type 2 diabetes mellitus. Saudi Med (2005); 26(1):73-77.
  • Akdogan M, Koyu A, Ciris M, Yildiz K. Anti-hypercholesterolemic activity of J. communis Lynn oil in rats: A biochemical and histopathological investigation. J Biomed Res 2012; 23(3):321-328.
  • Alberti KGMM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. provisional report of a WHO Consultation. Diabetic Med 1998; 15(7):539-553.
  • Alexandru N, Badila E, Weiss E, Cochior D, Stępień E, Georgescu A. Vascular complications in diabetes: Microparticles and microparticle associated MicroRNAs as active players. Biochem Biophys Res Commun 2016; 472(1):1-10.
  • Asgary S, Naderi GA, Shams Ardekani MR, et al. Inhibition of protein glycation by essential oils of branchlets and fruits of j. communis subsp. hemisphaerica. Res Pharm Sci 2014; 9(3):179–185.
  • Babu PV, Liu D, Gilbert ER. Recent advances in understanding the anti-diabetic actions of dietary flavonoids. J Nutr Biochem (2013); 24(11):1777-1789.
  • Barzilai A, Medina JA, Toth L, Dreiling DA. The effect of steroid administration on pancreatic secretion during and after hypovolemic shock. Int J Pancreatol (1986); 1(5-6):381-8.
  • Benjamin IJ, Griggs RC, Wing EJ, Gregory F. Andreoli and Carpenters Cecil essentials of medicine, 9th Edition, Elsevier /Saunders Philadelphia.2016.
  • Collier E, Watkinson A, Cleland CF, Roth J. Partial purification and characterization of an insulin-like material from spinach and Lemna gibba G3. J Biol Chem 1987; 262(13):6238-6247.
  • Das S, Mujib A, Das S, Pal S, Dey S. “Biotechnology of medicinal plants: Recent advances and potential”, in Role of biotechnology in medicinal and aromatic plants, Vol. 2, Ukaaz Publication, Hyderabad, India, 1998; 126-139.
  • Ferretti G, Bacchetti T, Marchionni C, Caldarelli L, Curatola G. Effect of glycation of high density lipoproteins on their physicochemical properties and on paraoxonase activity. Acta Diabetol (2001); 38(4):163-169.
  • Fowler MJ. Macro vascular and microvascular complications of diabetes. Clin Diabet 2008; 26(2):77-82.
  • Gallagher AM, Flatt PR, Duffy G, Abdel-Wahab YHA. The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr Res 2003; 23(3):413-424.
  • Gupta N, Binukumar BK, Singh S, et al. Serum paraoxonase-1 (PON1) activities (PONase/AREarease) and polymorphisms in patients with type 2 diabetes mellitus In A North-West Indian Population. Gene (2011); 487:88-95.
  • Habib SS, Aslam M. Risk factors, knowledge and health status in diabetic patients. Saudi Med J 2003; 24(11):1219-1224.
  • Hoferl M, Stoilova I, Schmidt E. et al. Chemical composition and antioxidant properties of Juniper berry (J. communis l.) essential oil. action of the essential oil on the antioxidant protection of Saccharomyces cerevisiae model organism. Antioxidants (2014); 3(1): 81-98.
  • Jae BP (1999). Flavonoids are potential inhibitors of glucose uptake in U937 cells. Biochem Biophys Res Commun 1999; 260(2):568–574.
  • Jelenković L, Jovanović VS, Palić I, Mitić V, Radulović M. In vitro screening of α-amylase inhibition by selected terpenes from essential oils. Trop J Pharmac Res (2014); 13(9):1421-1428.
  • Ju JB, Kim JS, Choi CW, Lee HK, Oh TK, Kim SC. Comparison between ethanolic and aqueous extracts from chinese juniper berries for hypoglycaemic and hypolipidemic effects in alloxan-induced diabetic rat. J Ethnopharmacol 2008; 115(1):110-5.
  • Jumepaeng T, Prachakool S, Luthria DL, Chanthai S. Determination of antioxidant capacity and α-amylase inhibitory activity of the essential oils from citronella grass and lemongrass. Int Food Res J (2013); 20(1):481-485.
  • Kar DM, Maharana L, Pattnaik S, Dash GK. Studies on hypoglycaemic activity of solanum xanthocarpum schrad. & wendl. fruit extract in rats. J Ethnopharmacol 2006; 108:251-256.
  • Karimi A, Majlesi M, Rafieian-Kopaei M. Herbal versus synthetic drugs; Beliefs and facts, J Nephropharmacol 2015; 4(1):27–30.
  • Kim JS, Kwon CS, Son KH. Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid. Bioscience Biotechnol Biochem (2000); 64(11):2458-2461.
  • Koren-Gluzer M, Aviram M, Meilin E, Hayek T. The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates β-cell insulin release. Atherosclerosis 2011; 219(2):510–518.
  • Kota SK, Meher LK, Kota SK, Jammula S, Krishna SV, Modi KD. Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia. Ind J Endoc Metab (2013); 17(3):402-412.
  • Kumar G, Banu GS, Murugesan, AG, Pandian MR. Hypoglycaemic effect of Helicteres isora bark extract in rats. J Ethnopharmacol 2006; 107(2):304–307.
  • Litvinov D, Mahini H, Garelnabi M. Antioxidant and anti-inflammatory role of paraoxonase 1; implication in arteriosclerosis diseases. N Am Med Sci 2012); 4(11):523-532.
  • Lohani H, Haider SZ, Chauhan NK, Sah S, Andola HC. Aroma profile of two Juniperus species from Alpine region in Uttarakhand. J Nat Prod (2013); 6:38-43.
  • Mackness B, Durrington PN, Boulton AJ, Hine D, Mackness MI. Serum paraoxonase activity in patients with type 1 diabetes compared to healthy controls. Eur J Clin Invest 2002; 32(4):259–264.
  • Miguel MG. Antioxidant and anti-inflammatory activities of essential oils. Molecules 2010; 15(12):9252-9287.
  • Najafian M, Ebrahim-Habibi A, Yaghmaei P, Parivar K, Larijani B. Citral AS. A Potential Antihyperlipidemic Medicine In Diabetes: A Study On Streptozotocin Induced Diabetic Rats. Diabet Metab Disord (2011); 10:1- 8.
  • Nakajima K, Nemoto T, Muneyuki T, Kakei M, Fuchigami H, Munakata H. Low serum amylase in association with metabolic syndrome and diabetes: A community-based study. Cardiovas Diabetol 2011; 10:34.
  • Nelson RW, Ihle SL, Lewis LD, et al. Effects of dietary fiber supplementation on glycemic control in dogs with alloxan-induced diabetes mellitus. Am Vet Res 1991; 52(12):2060-2066.
  • Petlevski R, Hadzija M, Slijepcevic M, Juretic D. Effect of ‘Antidiabetis’ herbal preparation on serum glucose and fructosamine in NOD mice. J Ethnopharmacol 2001; 75(2-3):181-4.
  • Prasath GS, Subramanian SP. Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats. Food Chem Toxicol 2013; 59:249-255.
  • Rahimi R, Nikfar S, Larijani B, Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother 2005; 59(7):365-373.
  • Seca AML, Silva AMS. Recent Progress in Medicinal Plants, Volume 16: Phytomedicines, Chapter: The chemical composition of the Juniperus genus (1970-2004), Publisher: Studium Press (India) Pvt. Ltd., Editors: Govil JN, Sing VK, Bhardwaj R. pp.401-522. 2005.
  • Senti M, Tomás M, Fito M, et al. antioxidant paraoxonase 1 activity in the metabolic syndrome. J Clin Endocrinol Metab (2003); 88(11):5422-6.
  • Steele AM, Shields BM, Wensley KJ, Colclough K, Ellard S, Hattersley AT. Prevalence of vascular complications among patients with glucokinase mutations among prolonged, mild hyperglycemia. JAMA 2014; 311(3):279-286.
  • Steinberg WM, Nauck MA, Zinman B, et al. Lipase and amylase activity in subjects with type 2 diabetes: Baseline data from over 9000 subjects in the LEADER Trial. Pancreas 2014; 43(8):1223-1231.
  • Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990; 33(8):462-4.
  • Turkoglu S, Bulmus FG, Parmaksız F, Özkan Y, Gursu F. Paraoxonase 1 and arylesterase activity levels in patients with metabolic sendrome. Fırat Tıp Derg 2008; (13(2):110-115.
  • Tuzmen I, Hafizoglu H. Terpene groups in essential oils of Juniperus L. cones and leaves of grown in Turkey. ZKU Bartin Faculty of Forestry Journal Vol I-II. 2004; 6(6):88-95.
  • Vardi N, Iraz M, Öztürk F, et al. Deneysel diyabetin sıçan böbreklerinde meydana getirdiği histolojik değişiklikler üzerine melatoninin iyileştirici etkileri. Inönü Üniv Tıp Fak Derg 2005; 12(3):145-152.
  • Venkatesh R, Sood D. A review of the physiological implications of antioxidants in food. bachelor of science interactive qualifying project. Worcester Polytechnic Institute 2011; 1(1083):1-37.
  • Williams E, Gokool N. An update on the role of plant sterols and stanols in the management of hypercholesterolaemia. CNmag 2005; 5:36-38.
  • World Health Organization. definition, diagnosis and classification of diabetes mellitus and its complications: Report of a who consultation, Part 1: Diagnosis and classification of diabetes mellitus. Geneva: World Health Organization 1999.
  • Young KH, Hui KM. Screening of Korean medicinal plants for lipase inhibitory activity. Phytother Res (2005); 19(4):359-360.

The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats

Year 2019, Volume: 3 Issue: 1, 13 - 20, 30.04.2019

Abstract

Objective:Juniperus communis (JC) oil, which is among the
medicinal plants,
has many pharmacological activities. In this study, effects of JC oil on serum paraoxonase and pancreatic enzymes levels, lipid levels in experimental diabetic rats were investigated.

Materials and Methods:Thirty
two
male
Wistar-Albino rats (250-300 g)
were used as material. The rats were divided into four groups of control (C),
diabetes (D),
JC oil (J),  and diabetes + JC
oil (DJ). D and DJ groups were treated with 45 mg/kg streptozotocin (STZ) (i.p.).
JC oil
(dissolved in distilled water (0.5% CMC)  was
administered as 200 mg/kg/21 days by oral gavage in J and DJ groups.

Results:Total
cholesterol (TC) and total 
triglyceride (TG) levels were observed to have significantly decreased in the J and DJ groups
to C and D groups (p≤0.001). There was no
difference in TG levels between D group and control group.
(p≥0.05). Lipoprotein levels were not statistically significant
among all groups
(p≥0.05). According to the
control group in the diabetes and DJ groups; significantly decreased amylase
levels and increased lipase levels
(p≤0.001).
Paraoxonase activity was have a significant
decrease in D group  (p≤0.05).
It was identified that the PON levels were
significantly
increase in the study groups when compared to the diabet
group (p≤0.05).

Conclusion:The application of JC oil was effective in
antihyperglycemia, antihyperlipidemic diabetes. In the other hand the
antioxidant PON caused an increase. As a result, it can be effective in
reducing the complications that may occur with lipids in diabetes.



References

  • Abdel-Moneim A, El-Feki M, Salah E. Effect of Nigella sativa, fish oil and gliclazide on alloxan diabetic rats 1-biochemical and histopathological studies. J Egy Ger Soci Zool 1997; 23:237-266.
  • Augsteen AA, Abu-Umair MS, Mahmoud SA. Biochemical analysis of serum pancreatic amylase and lipase enzymes in patients with type 1 and type 2 diabetes mellitus. Saudi Med (2005); 26(1):73-77.
  • Akdogan M, Koyu A, Ciris M, Yildiz K. Anti-hypercholesterolemic activity of J. communis Lynn oil in rats: A biochemical and histopathological investigation. J Biomed Res 2012; 23(3):321-328.
  • Alberti KGMM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. provisional report of a WHO Consultation. Diabetic Med 1998; 15(7):539-553.
  • Alexandru N, Badila E, Weiss E, Cochior D, Stępień E, Georgescu A. Vascular complications in diabetes: Microparticles and microparticle associated MicroRNAs as active players. Biochem Biophys Res Commun 2016; 472(1):1-10.
  • Asgary S, Naderi GA, Shams Ardekani MR, et al. Inhibition of protein glycation by essential oils of branchlets and fruits of j. communis subsp. hemisphaerica. Res Pharm Sci 2014; 9(3):179–185.
  • Babu PV, Liu D, Gilbert ER. Recent advances in understanding the anti-diabetic actions of dietary flavonoids. J Nutr Biochem (2013); 24(11):1777-1789.
  • Barzilai A, Medina JA, Toth L, Dreiling DA. The effect of steroid administration on pancreatic secretion during and after hypovolemic shock. Int J Pancreatol (1986); 1(5-6):381-8.
  • Benjamin IJ, Griggs RC, Wing EJ, Gregory F. Andreoli and Carpenters Cecil essentials of medicine, 9th Edition, Elsevier /Saunders Philadelphia.2016.
  • Collier E, Watkinson A, Cleland CF, Roth J. Partial purification and characterization of an insulin-like material from spinach and Lemna gibba G3. J Biol Chem 1987; 262(13):6238-6247.
  • Das S, Mujib A, Das S, Pal S, Dey S. “Biotechnology of medicinal plants: Recent advances and potential”, in Role of biotechnology in medicinal and aromatic plants, Vol. 2, Ukaaz Publication, Hyderabad, India, 1998; 126-139.
  • Ferretti G, Bacchetti T, Marchionni C, Caldarelli L, Curatola G. Effect of glycation of high density lipoproteins on their physicochemical properties and on paraoxonase activity. Acta Diabetol (2001); 38(4):163-169.
  • Fowler MJ. Macro vascular and microvascular complications of diabetes. Clin Diabet 2008; 26(2):77-82.
  • Gallagher AM, Flatt PR, Duffy G, Abdel-Wahab YHA. The effects of traditional antidiabetic plants on in vitro glucose diffusion. Nutr Res 2003; 23(3):413-424.
  • Gupta N, Binukumar BK, Singh S, et al. Serum paraoxonase-1 (PON1) activities (PONase/AREarease) and polymorphisms in patients with type 2 diabetes mellitus In A North-West Indian Population. Gene (2011); 487:88-95.
  • Habib SS, Aslam M. Risk factors, knowledge and health status in diabetic patients. Saudi Med J 2003; 24(11):1219-1224.
  • Hoferl M, Stoilova I, Schmidt E. et al. Chemical composition and antioxidant properties of Juniper berry (J. communis l.) essential oil. action of the essential oil on the antioxidant protection of Saccharomyces cerevisiae model organism. Antioxidants (2014); 3(1): 81-98.
  • Jae BP (1999). Flavonoids are potential inhibitors of glucose uptake in U937 cells. Biochem Biophys Res Commun 1999; 260(2):568–574.
  • Jelenković L, Jovanović VS, Palić I, Mitić V, Radulović M. In vitro screening of α-amylase inhibition by selected terpenes from essential oils. Trop J Pharmac Res (2014); 13(9):1421-1428.
  • Ju JB, Kim JS, Choi CW, Lee HK, Oh TK, Kim SC. Comparison between ethanolic and aqueous extracts from chinese juniper berries for hypoglycaemic and hypolipidemic effects in alloxan-induced diabetic rat. J Ethnopharmacol 2008; 115(1):110-5.
  • Jumepaeng T, Prachakool S, Luthria DL, Chanthai S. Determination of antioxidant capacity and α-amylase inhibitory activity of the essential oils from citronella grass and lemongrass. Int Food Res J (2013); 20(1):481-485.
  • Kar DM, Maharana L, Pattnaik S, Dash GK. Studies on hypoglycaemic activity of solanum xanthocarpum schrad. & wendl. fruit extract in rats. J Ethnopharmacol 2006; 108:251-256.
  • Karimi A, Majlesi M, Rafieian-Kopaei M. Herbal versus synthetic drugs; Beliefs and facts, J Nephropharmacol 2015; 4(1):27–30.
  • Kim JS, Kwon CS, Son KH. Inhibition of alpha-glucosidase and amylase by luteolin, a flavonoid. Bioscience Biotechnol Biochem (2000); 64(11):2458-2461.
  • Koren-Gluzer M, Aviram M, Meilin E, Hayek T. The antioxidant HDL-associated paraoxonase-1 (PON1) attenuates diabetes development and stimulates β-cell insulin release. Atherosclerosis 2011; 219(2):510–518.
  • Kota SK, Meher LK, Kota SK, Jammula S, Krishna SV, Modi KD. Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia. Ind J Endoc Metab (2013); 17(3):402-412.
  • Kumar G, Banu GS, Murugesan, AG, Pandian MR. Hypoglycaemic effect of Helicteres isora bark extract in rats. J Ethnopharmacol 2006; 107(2):304–307.
  • Litvinov D, Mahini H, Garelnabi M. Antioxidant and anti-inflammatory role of paraoxonase 1; implication in arteriosclerosis diseases. N Am Med Sci 2012); 4(11):523-532.
  • Lohani H, Haider SZ, Chauhan NK, Sah S, Andola HC. Aroma profile of two Juniperus species from Alpine region in Uttarakhand. J Nat Prod (2013); 6:38-43.
  • Mackness B, Durrington PN, Boulton AJ, Hine D, Mackness MI. Serum paraoxonase activity in patients with type 1 diabetes compared to healthy controls. Eur J Clin Invest 2002; 32(4):259–264.
  • Miguel MG. Antioxidant and anti-inflammatory activities of essential oils. Molecules 2010; 15(12):9252-9287.
  • Najafian M, Ebrahim-Habibi A, Yaghmaei P, Parivar K, Larijani B. Citral AS. A Potential Antihyperlipidemic Medicine In Diabetes: A Study On Streptozotocin Induced Diabetic Rats. Diabet Metab Disord (2011); 10:1- 8.
  • Nakajima K, Nemoto T, Muneyuki T, Kakei M, Fuchigami H, Munakata H. Low serum amylase in association with metabolic syndrome and diabetes: A community-based study. Cardiovas Diabetol 2011; 10:34.
  • Nelson RW, Ihle SL, Lewis LD, et al. Effects of dietary fiber supplementation on glycemic control in dogs with alloxan-induced diabetes mellitus. Am Vet Res 1991; 52(12):2060-2066.
  • Petlevski R, Hadzija M, Slijepcevic M, Juretic D. Effect of ‘Antidiabetis’ herbal preparation on serum glucose and fructosamine in NOD mice. J Ethnopharmacol 2001; 75(2-3):181-4.
  • Prasath GS, Subramanian SP. Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats. Food Chem Toxicol 2013; 59:249-255.
  • Rahimi R, Nikfar S, Larijani B, Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother 2005; 59(7):365-373.
  • Seca AML, Silva AMS. Recent Progress in Medicinal Plants, Volume 16: Phytomedicines, Chapter: The chemical composition of the Juniperus genus (1970-2004), Publisher: Studium Press (India) Pvt. Ltd., Editors: Govil JN, Sing VK, Bhardwaj R. pp.401-522. 2005.
  • Senti M, Tomás M, Fito M, et al. antioxidant paraoxonase 1 activity in the metabolic syndrome. J Clin Endocrinol Metab (2003); 88(11):5422-6.
  • Steele AM, Shields BM, Wensley KJ, Colclough K, Ellard S, Hattersley AT. Prevalence of vascular complications among patients with glucokinase mutations among prolonged, mild hyperglycemia. JAMA 2014; 311(3):279-286.
  • Steinberg WM, Nauck MA, Zinman B, et al. Lipase and amylase activity in subjects with type 2 diabetes: Baseline data from over 9000 subjects in the LEADER Trial. Pancreas 2014; 43(8):1223-1231.
  • Swanston-Flatt SK, Day C, Bailey CJ, Flatt PR. Traditional plant treatments for diabetes. Studies in normal and streptozotocin diabetic mice. Diabetologia 1990; 33(8):462-4.
  • Turkoglu S, Bulmus FG, Parmaksız F, Özkan Y, Gursu F. Paraoxonase 1 and arylesterase activity levels in patients with metabolic sendrome. Fırat Tıp Derg 2008; (13(2):110-115.
  • Tuzmen I, Hafizoglu H. Terpene groups in essential oils of Juniperus L. cones and leaves of grown in Turkey. ZKU Bartin Faculty of Forestry Journal Vol I-II. 2004; 6(6):88-95.
  • Vardi N, Iraz M, Öztürk F, et al. Deneysel diyabetin sıçan böbreklerinde meydana getirdiği histolojik değişiklikler üzerine melatoninin iyileştirici etkileri. Inönü Üniv Tıp Fak Derg 2005; 12(3):145-152.
  • Venkatesh R, Sood D. A review of the physiological implications of antioxidants in food. bachelor of science interactive qualifying project. Worcester Polytechnic Institute 2011; 1(1083):1-37.
  • Williams E, Gokool N. An update on the role of plant sterols and stanols in the management of hypercholesterolaemia. CNmag 2005; 5:36-38.
  • World Health Organization. definition, diagnosis and classification of diabetes mellitus and its complications: Report of a who consultation, Part 1: Diagnosis and classification of diabetes mellitus. Geneva: World Health Organization 1999.
  • Young KH, Hui KM. Screening of Korean medicinal plants for lipase inhibitory activity. Phytother Res (2005); 19(4):359-360.
There are 49 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section 2019 Volume 3 Number 1
Authors

Evan Abdulkarim Mahmood This is me 0000-0002-1960-8951

Tahir Kahraman

Publication Date April 30, 2019
Submission Date March 11, 2019
Published in Issue Year 2019 Volume: 3 Issue: 1

Cite

APA Mahmood, E. A., & Kahraman, T. (2019). The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats. Turkish Journal of Veterinary Research, 3(1), 13-20.
AMA Mahmood EA, Kahraman T. The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats. TJVR. April 2019;3(1):13-20.
Chicago Mahmood, Evan Abdulkarim, and Tahir Kahraman. “The Effects of Juniperus Communis (Cupressaceae) Oil Application on the Serum Paraoxonase and Pancreatic Enzymes Activities and Lipid Levels in Experimental Diabetic Rats”. Turkish Journal of Veterinary Research 3, no. 1 (April 2019): 13-20.
EndNote Mahmood EA, Kahraman T (April 1, 2019) The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats. Turkish Journal of Veterinary Research 3 1 13–20.
IEEE E. A. Mahmood and T. Kahraman, “The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats”, TJVR, vol. 3, no. 1, pp. 13–20, 2019.
ISNAD Mahmood, Evan Abdulkarim - Kahraman, Tahir. “The Effects of Juniperus Communis (Cupressaceae) Oil Application on the Serum Paraoxonase and Pancreatic Enzymes Activities and Lipid Levels in Experimental Diabetic Rats”. Turkish Journal of Veterinary Research 3/1 (April 2019), 13-20.
JAMA Mahmood EA, Kahraman T. The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats. TJVR. 2019;3:13–20.
MLA Mahmood, Evan Abdulkarim and Tahir Kahraman. “The Effects of Juniperus Communis (Cupressaceae) Oil Application on the Serum Paraoxonase and Pancreatic Enzymes Activities and Lipid Levels in Experimental Diabetic Rats”. Turkish Journal of Veterinary Research, vol. 3, no. 1, 2019, pp. 13-20.
Vancouver Mahmood EA, Kahraman T. The effects of Juniperus communis (Cupressaceae) oil application on the serum paraoxonase and pancreatic enzymes activities and lipid levels in experimental diabetic rats. TJVR. 2019;3(1):13-20.