Objective: This study aimed to investigate the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats.
Material and Method: Experimental groups were created as control, sham, chia, dandelion, diabetes (DM), diabetes+chia (DC), and diabetes +dandelion (DD). Body weight and blood glucose measurements were taken on the 1st, 3rd, and 17th days of the study and evaluated statistically. A one-way ANOVA test was performed to determine the differences between the groups. The Duncan test was used to compare significant differences between groups. At the end of the study, Masson's trichrome staining and Hematoxylin-Eosin staining were employed for histological examinations of liver tissues, and the distribution of TNF-α and IL-6 was examined by applying the Streptavidin-biotin peroxidase method.
Results: It was determined that body weight and blood glucose measurements were significantly decrease for the DC group compared to other groups. Immunoreactivity of TNF-α and IL-6 was found to decrease in DC and DD groups at close to the control levels.
Conclusion: Based on our results, it was thought that the use of chia and dandelion in diabetes may contribute to the alleviation of disease-related complications by having a positive effect on proinflammatory cytokine levels.
Primary Language | English |
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Subjects | Veterinary |
Journal Section | 2022 Volume 6 Number 2 |
Authors |
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Supporting Institution | Kafkas University Scientific Research Projects Coordinator |
Project Number | 2019-TS-63 |
Early Pub Date | November 21, 2022 |
Publication Date | November 25, 2022 |
Submission Date | March 9, 2022 |
Acceptance Date | June 6, 2022 |
Published in Issue | Year 2022 Volume: 6 Issue: 2 |
Bibtex | @research article { tjvr1062162, journal = {Turkish Journal of Veterinary Research}, eissn = {2602-3695}, address = {}, publisher = {Ebubekir CEYLAN}, year = {2022}, volume = {6}, number = {2}, pages = {43 - 52}, doi = {10.47748/tjvr.1062162}, title = {Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats}, key = {cite}, author = {Aras, Şükran and Aksu Kılıçle, Pinar and Eliş Yıldız, Sevda and Uluman, Erhan and Bakır, Buket and Karadağ Sarı, Ebru and Dağ, Serpil} } |
APA | Aras, Ş. , Aksu Kılıçle, P. , Eliş Yıldız, S. , Uluman, E. , Bakır, B. , Karadağ Sarı, E. & Dağ, S. (2022). Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats . Turkish Journal of Veterinary Research , 6 (2) , 43-52 . DOI: 10.47748/tjvr.1062162 |
MLA | Aras, Ş. , Aksu Kılıçle, P. , Eliş Yıldız, S. , Uluman, E. , Bakır, B. , Karadağ Sarı, E. , Dağ, S. "Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats" . Turkish Journal of Veterinary Research 6 (2022 ): 43-52 <https://dergipark.org.tr/en/pub/tjvr/issue/73416/1062162> |
Chicago | Aras, Ş. , Aksu Kılıçle, P. , Eliş Yıldız, S. , Uluman, E. , Bakır, B. , Karadağ Sarı, E. , Dağ, S. "Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats". Turkish Journal of Veterinary Research 6 (2022 ): 43-52 |
RIS | TY - JOUR T1 - Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats AU - ŞükranAras, PinarAksu Kılıçle, SevdaEliş Yıldız, ErhanUluman, BuketBakır, EbruKaradağ Sarı, SerpilDağ Y1 - 2022 PY - 2022 N1 - doi: 10.47748/tjvr.1062162 DO - 10.47748/tjvr.1062162 T2 - Turkish Journal of Veterinary Research JF - Journal JO - JOR SP - 43 EP - 52 VL - 6 IS - 2 SN - -2602-3695 M3 - doi: 10.47748/tjvr.1062162 UR - https://doi.org/10.47748/tjvr.1062162 Y2 - 2022 ER - |
EndNote | %0 Turkish Journal of Veterinary Research Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats %A Şükran Aras , Pinar Aksu Kılıçle , Sevda Eliş Yıldız , Erhan Uluman , Buket Bakır , Ebru Karadağ Sarı , Serpil Dağ %T Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats %D 2022 %J Turkish Journal of Veterinary Research %P -2602-3695 %V 6 %N 2 %R doi: 10.47748/tjvr.1062162 %U 10.47748/tjvr.1062162 |
ISNAD | Aras, Şükran , Aksu Kılıçle, Pinar , Eliş Yıldız, Sevda , Uluman, Erhan , Bakır, Buket , Karadağ Sarı, Ebru , Dağ, Serpil . "Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats". Turkish Journal of Veterinary Research 6 / 2 (November 2022): 43-52 . https://doi.org/10.47748/tjvr.1062162 |
AMA | Aras Ş. , Aksu Kılıçle P. , Eliş Yıldız S. , Uluman E. , Bakır B. , Karadağ Sarı E. , Dağ S. Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats. TJVR. 2022; 6(2): 43-52. |
Vancouver | Aras Ş. , Aksu Kılıçle P. , Eliş Yıldız S. , Uluman E. , Bakır B. , Karadağ Sarı E. , Dağ S. Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats. Turkish Journal of Veterinary Research. 2022; 6(2): 43-52. |
IEEE | Ş. Aras , P. Aksu Kılıçle , S. Eliş Yıldız , E. Uluman , B. Bakır , E. Karadağ Sarı and S. Dağ , "Determination of the effects of Chia (Salvia hispanica L.) oil and Dandelion (Taraxacum Officinale) extract on Tumor Necrosis Factor-α (TNF-α) and Interleukin 6 (IL-6) release in liver tissue of diabetic rats", Turkish Journal of Veterinary Research, vol. 6, no. 2, pp. 43-52, Nov. 2022, doi:10.47748/tjvr.1062162 |
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