Aims: To investigate modern methods to prevent premature rupture of membranes by the use of chlorhexidine in
pregnant women with varicose disease.
Methods: The data of 39 pregnant women with varicose disease, who delivered between 2014 and 2016 at Maternity
Hospital No. 3, Zaporozhye were analyzed using SPSS software. Patients were divided in 3 groups according to
their medical history, complications during pregnancy, childbirth and postpartum period. The 1st group consisted
of 13 pregnant women who did not receive prenatal vaginal douching with chlorhexidine; the 2nd group consisted
of 13 patients with varicose disease, who received douching of birth canal with vaginal suppositories with chlorhexidine
1 time per day for 10 days before their delivery, but did not undergo a rehabilitation at the sanatorium; and the
3rd group had 13 pregnant women who received sanatorium rehabilitation at ‘‘Veliki lug’’ during the II. trimester of
their pregnancy with the course of 1 chlorhexidine suppository per day for 10 days before delivery.
Results:In the 1st group, the percentage of premature death was 61.5%; anemia and significant ultrasound markers
were present in 46.2%; the percentage for the presence of hematometra was 38.5%; premature rupture of membranes,
anomalies of labor and polyhydroamniosis were 30.8%; chorioamnionitis 15.4%; and intrauterine infection of
fetus was 7.7%. In the 2nd group, anemia was present in 35%, 23.1% showed anomalies of labor; premature rupture
of membranes, ultrasound markers, premature death, and hematometra were present in 15.4%. Whereas in the 3rd
group, anemia and anomalies of labor were present in 15.4%, premature rupture of the membranes and premature
death were present in 7.7% of the patients.
Conclusion: With its broad antibacterial and antiviral effect, chlorhexidine in antiseptic form was found to be
beneficial and it is found to promote the restoration of the vaginal microflora.
Primary Language | English |
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Journal Section | Research Article |
Authors | |
Publication Date | February 25, 2018 |
Submission Date | December 29, 2017 |
Published in Issue | Year 2018 Volume: 5 Issue: 1 |