Neurodevelopmental and psychiatric assessments at corrected age of 1 3 years in very preterm infants

Abstract

Aim: To assess the neurodevelopmental and psychiatric outcomes of very preterm vs preterm infants at 1 3 years of corrected age Material and Method: Between years 2005 2008 premature infants followed up in the NICU designated as Group 1 lt;32 wks;n=36 were evaluated in comparison to Group 2 33 37wks; n=56 with the approval of Ethics Committee TUTFEK 2008 083 in terms of neurodevelopmental and psychiatric development by using Denver developmental screening test the brief infant toddler social emotional assessment childcare provider version Mothers rsquo; psychiatric symptoms were assessed by the brief symptom inventory Socioeconomic status was determined by using SES scale t test or Mann Whitney U tests chi square and Spearman tests were used for statistical analysis Results: In Group 1 paternal education level and psychodevelopmental score was lower than group 2 abnormal outcome in Denver developmental test was more frequent Psychiatric problem score was higher in boys whereas psychodevelopmental score was higher in girls Psychosocial developmental score was lower in those infants with intraventricular hemorrhage and this score showed positive correlation with Denver developmental test results There was no difference between the two groups in terms of brief symptom inventory Conclusions: Although very preterm infants more frequently showed abnormal neuropsychological development they were not significantly different with regard to psychiatric problems Girls were more advantegous than boys in terms of psychodevelopment We conclude that these findings should be validated by larger and further studies Turk Arch Ped 2011; 46: 280 5

Keywords

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İleri derecede erken doğmuş yenidoğanların düzeltilmiş 1 3 yaşlarındaki nörogelişimsel ve psikiyatrik değerlendirmesi

Öz

Amaç: İleri derecede erken doğmuş yenidoğanlarla orta derecede ve sınırda erken doğmuş yenidoğanların düzeltilmiş 1 3 yaşlarındaki gelişimsel ve psikiyatrik değerlendirme sonuçlarının karşılaştırılması. 

Gereç ve Yöntem: 2005 2008 tarihleri arasında Yenidoğan Birimi rsquo;nde izlenen grup 1 lt;32 gebelik haftası;n=36 ve grup 2 rsquo;deki 33 37 gebelik haftası; n=56 yenidoğanlar Etik Kurul onayı alınarak TÜTFEK 2008 083 düzeltilmiş 13 yaşlarındaki Denver gelişimsel testi ve kısa 1 3 yaş sosyal duygusal değerlendirme ölçeği ile gelişimsel sosyal duygusal ve psikiyatrik sorunlar yönünden değerlendirildi Annelerine kısa semptom envanteri uygulandı Ailelerin sosyoekonomik durumu sosyo ekonomik durum ölçeğiyle belirlendi İstatistiksel analizde t testi veya Mann Whitney U testi ki kare ve Spearman testi kullanıldı

Bulgular: Grup 1 rsquo;de baba eğitim düzeyi psikogelişimsel skor ortalaması grup 2 rsquo;ye göre daha düşük anormal Denver gelişim test oranı daha yüksek saptandı Psikiyatrik sorun skoru erkeklerde psikososyal gelişim skoru ise kızlarda daha yüksekti Psikososyal gelişim skoru ventrikül içine kanaması olanlarda daha düşüktü ve bu skor ile Denver gelişim tesiti arasında pozitif ilişki saptandı Kısa semptom envanteri açısından farklılık yoktu.

Çıkarımlar: İleri derecede erken doğmuş yenidoğanlar daha sık anormal nöropsikolojik gelişim gösterdikleri halde psikiyatrik sorun açısından farklı bulunmadılar Psikogelişimsel yönden kızlar erkeklere göre daha önde idi Bu bulguların daha geniş ve ileri çalışmalarla desteklenmesi gerektiği sonucuna varıldı.

Anahtar Kelimeler

• Erken doğmuş bebek
• ileri derecede erken doğmuş bebek
• nörogelişim
• psikiyatrik değerlendirme

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