Retrospective Study of 62 Acute Idiopathic Thrombocytopenic Purpura Cases

Abstract

Sixty two cases of acute idiopathic thrombocytopenic purpura ITP were evaluated according to clinical and laboratory findings treatment and prognosis retrospectively Male female ratio was 23 1 and 33 9 of the patients were aged between 4 and 6 years The peak seasonal incidence was in the spring 68 History of upper respiratory tract infection was found in 39 of the cases The most clinical findings were purpura epistaxis and gingival hemorrhage 100 29 and 19 4 respectively nbsp; In the cases with Hb lt; 8 gr dl 8 1 Hct lt; 25 11 3 or thrombocyte count lt; 20 000 mm3 8 1 skin and mucosal hemorrhage were associated with hematemesis and melena Spontaneous remission rate was 54 8 corticosteroids were used in 37 1 of the cases and full remission was observed in 60 9 of them In 5 cases 8 9 intravenous immunoglobulin was used and 3 of them showed full remission while 2 of them relapsed Splenectomy was not performed during the acute phase in any of the cases Only 3 cases showed cronicity Key words: Idiopathic Thrombosytopenic Purpura Acute Thrombocyetopenia

Keywords

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Akut İdiopatik Trombositopenik Purpura: 62 Olgunun Retrospektif İncelenmesi

Öz

Ocak 1987 Aralık 1991 tarihleri arasında akut idiopatik trombositopenik purpura İTP tanısı konulmuş 62 olgu klinik laboratuvar bulguları tedavi ve sonuçlan bakımından retrospektif olarak incelendi nbsp; Erkek kız oranı 23:1 en çok görüldüğü yaş 33 9 oranı ile 4 6 yaş mevsimsel dağılımı 68 olgu ile ilkbahardı Olguların 39 unun anamnezinde geçirilmiş üst solunum yolu enfeksiyonu ÜSYE hikayesi mevcuttu En çok gözlenen klinik bulgular purpura 100 epistaksis 29 diş eti kanaması 19 4 idi Hb lt;8 gr dl 8 1 Hct lt; 25 11 3 trombosit lt; 20 000 mm3 8 1 olan olgularda hematemez melena diğer cilt ve mukoza kanamaları ile birlikte gözlendi Spontan remisyon 54 8 kortikosteroid kullanılması 37 1 kortikosteoride tam cevap ise bunların 60 9 unda tespit edildi İntravenöz immunoglobulin verilen 5 8 1 olgudan üçünde tam düzelme 2 olguda rölaps oldu Hiçbir olguda akut dönemde splenektomi yapılmadı Sadece 3 olgu kronikleşti Anahtar kelimeler: İdiopatik Trombositopenik Purpura Akut Trombositopeni

Anahtar Kelimeler

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