Dietary therapies for childhood epilepsy

Abstract

Ketogenic diet composed of high fat and low carbonhydrate was introduced as a therapeutic alternative for epilepsy in early 20 rsquo;s As new antiepileptic agents such as phenytoin were discovered popularity of the diet was waned until 90 rsquo;s Studies on efficacy of diet in refractory epilepsy reported that approximately half of the children had a significant reduction 15 of whom were seizure free With growing body of evidence and introduction of diet modifications ketogenic diet was promoted as a first line treatment for epileptic encephalopathies such as myoclonic astatic epilepsy Dravet syndrome and infantile spasm Turk Arch Ped 2013; 48: 275 80

Keywords

• Dravet syndrome, epilepsy, infantile spasm, ketogenic diet, myoclonic astatic epilepsy

Çocukluk çağı epilepsilerinde diyet tedavisi

Öz

Besin alerjisi besin proteinlerine karşı geliştirilen spesifik IgE antikorları aracılığı ile ortaya çıkan Tip I aşırı duyarlılık reaksiyonu olarak tanımlanmaktadır Dünyada olduğu gibi ülkemizde de tüm alerjik hastalıklarda olduğu gibi besin alerjisinin görülme sıklığı giderek artmaktadır Anne baba ya da kardeşlerinde alerjik rinit bronşiyal astım atopik dermatit ve besin alerjisi gibi alerjik etiolojiye dayalı bir hastalık bulunan bebekler besin allerjisi açısından yüksek risk grubundadırlar Besin alerjisi yönünden risk grubunda bulunan bebeklere uygulanması gereken tanı ve tedavi yöntemlerinin belirlenmesi doğru tanı ve tedavinin yapılabilmesinde yararlı olacaktır ldquo;Çocuk Alerji ve Astım Akademisi Derneği rdquo; olarak hazırladığımız bu protokolün amacı; ldquo;Aile Hekimleri rdquo; ve ldquo;Çocuk Sağlığı ve Hastalıkları Uzmanları rdquo; için besin alerjilerinin tanınması ve tedavisi konusunda bir kaynak olarak yol gösterici olmaktır Türk Ped Arfl 2013; 48: 270 4

Anahtar Kelimeler

• Dravet sendromu, epilepsi, ketojenik diyet, miyoklonik astatik epilepsi, süt çocuğı spazmı

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