A very rare complication of type 1 diabetes: insulin edema developed in a newly diagnosed type 1 diabetes
Abstract
Edema caused by insulin therapy is a rare complication Here we report a 13 year old boy with newly diagnosed type 1 diabetes who developed edema in lower extremities in the third day of insulin therapy After exclusion of other causes leading to edema we diagnosed insulin edema which has been very rarely reported in children Within 7 days of insulin therapy edema resolved spontaneously In newly diagnosed type 1 diabetic children and adolescents insulin induced edema should be considered after the initiation of insulin therapy Turk Arch Ped 2013; 48: 62 4
References
- Hopkins DF, Cotton SJ, Williams G. Effective treatment of insulin-induced edema using ephedrine. Diabetes Care 1993(7); 16: 1026-28.
- Leifer A. A case of insulin edema. JAMA 1928; 90: 610-1.
- Juliusson PB, Bjerknes R, Sovik O, Kvistad PH. Generalized edema following insulin treatment of newly diagnosed diabetes mellitus. Tidsskr Nor Laegeforen 2001; 121(8): 919-20.
- Chelliah A, Burge MR. Insulin edema in the twenty-first century: review of the existing literature. J Invest Med 2004(2); 52: 104-8.
- Bleach NR, Dunn PJ, Khalafalla ME, McConkey B. Insulin edema. Br Med J 1979(6183); 21: 177-8.
- Hirschberg B, Muszkat M, Marom T, Shalit M. Natural course of insulin edema. J Endocrinol Invest 2000; 23: 187-8.
- Dornan TL, Jenkins S, Cotton RE, Tattersall RB, Burden RP. The nephrotic syndrome at presentation of insulin-dependent diabetes mellitus; cause or coincidence? Diabet Med 1988; 5: 387-90.
- Evans DJ, Pritchard-Jones K, Trotman-Dickenson B. Insulin oedema. Postgrad Med J 1986; 62: 665-8.
- Zenda T, Murase Y, Yoshida I, Muramoto H, Okada T, Yagi K. Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin edema? Eur J Gastroenterol Hepatol 2003; 15(5): 545-9.
- DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ. The effect of insulin on renal handling of sodium, potassium, calcium and phosphate in man. J Clin Invest 1975; 55(4): 845-55.
- Kalambokis GN, Tsatsoulis AA, Tsianos EV. The edematogenic properties of insulin. Am J Kidney Dis 2004(4); 44: 575-90.
- Klisic J, Hu MC, Nief V, et al. Insulin activates Na(+)/H(+) exchanger 3: biphasic response and glucocorticoid dependence. Am J Physiol Renal Physiol 2002; 283(3): 532-9.
- Şekil 1. Her iki bacakta ödem 63 Şen ve ark. TİP 1 diyabetin çok nadir bir komplikasyonu / A very rare complication of type 1 diabetes Türk Ped Arfl 2013; 48: 62-4 Turk Arch Ped 2013; 48: 62-4
Abstract
İnsülin tedavisi sırasında insüline bağlı ödem gelişmesi oldukça seyrek görülen bir komplikasyondur Yeni tanı almış tip 1 diyabetli 13 yaşındaki erkek çocuk insülin tedavisinin üçüncü gününde bacaklarında gelişen ödem nedeniyle sunulmaktadır Ödeme yol açtığı bilinen nedenlerin dışlanmasından sonra oldukça seyrek bildirilmiş olan insüline bağlı ödem tanısı konulmuştur İnsülin tedavisinin yedinci gününde ödemin kendiliğinden gerilediği gözlendi Özellikle yeni tanı almış tip 1 diyabetli çocuklarda ve ergenlerde insülin tedavisi başlandıktan sonra gelişen ödemin insüline bağlı olabileceği düşünülmelidir.
References
- Hopkins DF, Cotton SJ, Williams G. Effective treatment of insulin-induced edema using ephedrine. Diabetes Care 1993(7); 16: 1026-28.
- Leifer A. A case of insulin edema. JAMA 1928; 90: 610-1.
- Juliusson PB, Bjerknes R, Sovik O, Kvistad PH. Generalized edema following insulin treatment of newly diagnosed diabetes mellitus. Tidsskr Nor Laegeforen 2001; 121(8): 919-20.
- Chelliah A, Burge MR. Insulin edema in the twenty-first century: review of the existing literature. J Invest Med 2004(2); 52: 104-8.
- Bleach NR, Dunn PJ, Khalafalla ME, McConkey B. Insulin edema. Br Med J 1979(6183); 21: 177-8.
- Hirschberg B, Muszkat M, Marom T, Shalit M. Natural course of insulin edema. J Endocrinol Invest 2000; 23: 187-8.
- Dornan TL, Jenkins S, Cotton RE, Tattersall RB, Burden RP. The nephrotic syndrome at presentation of insulin-dependent diabetes mellitus; cause or coincidence? Diabet Med 1988; 5: 387-90.
- Evans DJ, Pritchard-Jones K, Trotman-Dickenson B. Insulin oedema. Postgrad Med J 1986; 62: 665-8.
- Zenda T, Murase Y, Yoshida I, Muramoto H, Okada T, Yagi K. Does the use of insulin in a patient with liver dysfunction increase water retention in the body, i.e. cause insulin edema? Eur J Gastroenterol Hepatol 2003; 15(5): 545-9.
- DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ. The effect of insulin on renal handling of sodium, potassium, calcium and phosphate in man. J Clin Invest 1975; 55(4): 845-55.
- Kalambokis GN, Tsatsoulis AA, Tsianos EV. The edematogenic properties of insulin. Am J Kidney Dis 2004(4); 44: 575-90.
- Klisic J, Hu MC, Nief V, et al. Insulin activates Na(+)/H(+) exchanger 3: biphasic response and glucocorticoid dependence. Am J Physiol Renal Physiol 2002; 283(3): 532-9.
- Şekil 1. Her iki bacakta ödem 63 Şen ve ark. TİP 1 diyabetin çok nadir bir komplikasyonu / A very rare complication of type 1 diabetes Türk Ped Arfl 2013; 48: 62-4 Turk Arch Ped 2013; 48: 62-4
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 1, 2013 |
| Published in Issue | Year 2013 Volume: 48 Issue: 1 |