Nocturnal enuresis

Year 2012, Volume: 47 Issue: 2, 78 - 83, 01.06.2012

R. Yavuz Akman

https://doi.org/10.4274/tpa.1626

Abstract

Nocturnal enuresis is one of the most common urinary problems in children and is observed in about 15 20 percent of children 5 years of age Nocturnal enuresis resolves at a rate of 15 per year so 99 of children are dry by the age of fifteen years Enuresis can be defined as repetative bed wetting while sleeping Enuresis in children without any other lower urinary tract LUT symptoms excluding nocturia and without a history of bladder dysfunction is defined as monosymptomatic enuresis Most of the enuretic children belong to this group A bladder dysfunction must be kept in mind in an enuretic child having day time symptoms Behavioral treatment approaches alarm treatment and pharmacological treatment are the most frequently used approaches for treatment In all treatment modalities and especially in alarm treatment the motivation and active involvement of the family and the child are very important Turk Arch Ped 2012; 47: 78 83

Keywords

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Noktürnal enürezis

Abstract

Uykuda yatağa tekrarlayan bir şekilde idrar kaçırmak enürezis olarak tanımlanır Noktürnal enürezis çocukluklarda en sık karşılaşılan üriner problemlerden biridir ve beş yaşındaki çocukların yaklaşık 15 20 rsquo;sinde gözlenir Noktürnal enürezis her yıl 15 hızında iyileşme gösterir böylece on beş yaşındaki çocukların 99 rsquo;u kurudur Beraberinde noktüri dışında başka hiç alt üriner sistem belirtileri ve mesane işlev bozukluğu öyküsü olmayan çocuklardaki enürezis monosemptomatik noktürnal enürezistir Noktürnal enürezisli çocukların büyük bir kısmını bu grup oluşturmaktadır Gündüz semptomlu bir enüretik çocukta altta yatan bir mesane işlev bozukluğu olasılığı akılda tutulmalıdır Tedavide destekleyici tedavi yöntemleri alarm ve ilaç tedavileri en sık kullanılan yöntemlerdir Bu tedavi yöntemlerinin tümünde ama özellikle alarm tedavisinde aile ve çocuğun isteği ve etkin katılımı çok önemlidir.

Keywords

Enkontinans, enüretik alarm, desmopressin

References

• Gill D. Enuresis through the ages. Pediatr Nephrol 1995;9:120-2.
• Neveus T, von Gontard A, Hoebeke P, et al. The standardization of terminology of lower urinary tract function in children and adolescents: report from the Standardisation Committee of the International Children's Continence Society. J Urol 2006;176:314-24.
• Rassouli R, Holschneider AM, Bolkenius M, et al. Long-term results of Rehbein's procedure: a retrospective study in German-speaking countries. Eur J Pediatr Surg 2003;13:187-94.
• Yeung CK. Nocturnal enuresis (bedwetting). Curr Opin Urol 2003;13:337-43.
• Yeung CK, Sreedhar B, Sihoe JD, Sit FK, Lau T. Differences in characteristics of nocturnal enuresis between children and adolescents: a critical appraisal from a large epidemiological study. BJU Int 2006;97:1069-73.
• Forsythe WI, Redmond A. Enuresis and spontaneous cure rate. Study of 1129 enuretis. Arch Dis Child 1974;49:259-63.
• Serel TA, Akhan G, Koyuncuoglu HR, et al. Epidemiology of enuresis in Turkish children. Scand J Urol Nephrol 1997;31:537-9.
• Gur E, Turhan P, Can G, et al. Enuresis: prevalence, risk factors and urinary pathology among school children in Istanbul, Turkey. Pediatr Int 2004;46:58-63.
• Moore KH, Richmond DH, Parys BT. Sex distribution of adult idiopathic detrusor instability in relation to childhood bedwetting. Br J Urol 1991;68:479-82.
• von Gontard A, Schaumburg H, Hollmann E, Eiberg H, Ritting S. The genetics of enuresis: a review. J Urol 2001;166:2438-43.
• Bakwin H. Enuresis in children. J Pediatr 1961;58:806-19.
• Elian M, Elian E, Kaushansky A. Nocturnal enuresis: a familial condition. J R Soc Med 1984;77:529-30.
• von Gontard A, Hollmann E, Eiberg H, Benden B, Rittig S, Lehmkuhl G. Clinical enuresis phenotypes in familial nocturnal enuresis. Scand J Urol Nephrol Suppl 1997;183:11-6.
• von Gontard A, Heron J, Joinson C. Family history of nocturnal enuresis and urinary incontinence: results from a large epidemiological study. J Urol 2011;185:2303-7.
• Jarvelin MR, Vikevainen-Tervonen L, Moilanen I, Huttunen ND. Enuresis in seven-year-old children. Acta Paediatr Scand 1988;77:148-53.
• Bakwin H. Enuresis in twins. Am J Dis Child 1971;121:222-5.
• Arnell H, Hjalmas K, Jagervall M, et al. The genetics of primary nocturnal enuresis: inheritance and suggestion of a second major gene on chromosome 12q. J Med Genet 1997;34:360-5.
• Eiberg H. Total genome scan analysis in a single extended family for primary nocturnal enuresis: evidence for a new locus (ENUR3) for primary nocturnal enuresis on chromosome 22q11. Eur Urol 1998; 33 Suppl 3:34-6.
• Eiberg H, Berendt I, Mohr J. Assignment of dominant inherited nocturnal enuresis (ENUR1) to chromosome 13q. Nat Genet 1995;10:354-6.
• Robson WL. Current management of nocturnal enuresis. Curr Opin Urol 2008;18:425-30.
• George CP, Messerli FH, Genest J, Nowaczynski W, Boucher R, Kuchel Orofo-Oftega M. Diurnal variation of plasma vasopressin in man. J Clin Endocrinol Metab 1975;41:332-8.
• Rittig S, Knudsen UB, Norgaard JP, Pedersen EB, Djurhuus JC. Abnormal diurnal rhythm of plasma vasopressin and urinary output in patients with enuresis. Am J Physiol 1989;256:F664-71.
• Watanabe H, Kawauchi A. Is small bladder capacity a cause of enuresis? Scand J Urol Nephrol Suppl 1995;173:37-41.
• Watanabe H. Nocturnal enuresis. Eur Urol 1998;33 Suppl 3:2-11.
• Neveus T. Nocturnal enuresis-theoretic background and practical guidelines. Pediatr Nephrol 2011;26:1207-14.
• Bader G, Neveus T, Kruse S, Sillen U. Sleep of primary enuretic children and controls. Sleep 2002;25:579-83.
• Cinar U, Vural C, Cakir B, Topuz E, Karaman MI, Turgut S. Nocturnal enuresis and upper airway obstruction. Int J Pediatr Otorhinolaryngol 2001;59:115-8.
• Neveus T, Eggert P, Evans J, et al. Evaluation of and treatment for monosymptomatic enuresis: a standardization document from the International Children's Continence Society. J Urol 2010;183:441-7.
• Glazener CM, Evans JH. Simple behavioural and physical interventions for nocturnal enuresis in children. Cochrane Database Syst Rev 2004:CD003637.
• Glazener CM, Evans JH, Peto RE. Alarm interventions for nocturnal enuresis in children. Cochrane Database Syst Rev 2005:CD002911.
• Butler RJ, Holland P, Gasson S, Norfolk S, Houghton L, Penney M. Exploring potential mechanisms in alarm treatment for primary nocturnal enuresis. Scand J Urol Nephrol 2007;41:407-13.
• Oredsson AF, Jorgensen TM. Changes in nocturnal bladder capacity during treatment with the bell and pad for monosymptomatic nocturnal enuresis. J Urol 1998;160:166-9.
• Glazener CM, Evans JH. Desmopressin for nocturnal enuresis in children. Cochrane Database Syst Rev 2002:CD002112.
• Meltzer LJ, Johnson C, Crosette J, Ramos M, Mindell JA. Prevalence of diagnosed sleep disorders in pediatric primary care practices. Pediatrics 2010;125:e1410-8.
• Hunsballe JM, Hansen TK, Rittig S, Pedersen EB, Djurhuus JC. The efficacy of DDAVP is related to the circadian rhythm of urine output in patients with persisting nocturnal enuresis. Clin Endocrinol (Oxf) 1998;49:793-801.
• Wille S. Comparison of desmopressin and enuresis alarm for nocturnal enuresis. Arch Dis Child 1986;61:30-3.
• Maclean RE. Imipramine hydrochloride (Tofranil) and enuresis. Am J Psychiatry 1960;117:551.
• Glazener CM, Evans JH, Peto RE. Tricyclic and related drugs for nocturnal enuresis in children. Cochrane Database Syst Rev 2003:CD002117.
• Smellie JM, McGrigor VS, Meadow SR, Rose SJ, Douglas MF. Nocturnal enuresis: a placebo controlled trial of two antidepressant drugs. Arch Dis Child 1996;75:62-6.
• Fritz GK, Rockney RM, Yeung AS. Plasma levels and efficacy of imipramine treatment for enuresis. J Am Acad Child Adolesc Psychiatry 1994;33:60-4.
• Swanson JR, Jones GR, Krasselt W, Denmark LN, Ratti F. Death of two subjects due to imipramine and desipramine metabolite accumulation during chronic therapy: a review of the literature and possible mechanisms. J Forensic Sci 1997;42:335-9.
• Kosar A, Arikan N, Dincel C. Effectiveness of oxybutynin hydrochloride in the treatment of enuresis nocturna--a clinical and urodynamic study. Scand J Urol Nephrol 1999;33:115-8.
• Avanoğlu A, Baskın E, Söylemezoğlu O, Tekgül S, Zilan O, Zorludemir Ü. Türkiye Enürezis Çalışma Grubu. İçinde: Türkiye Enürezis Tedavi Kılavuzu 2010;1-16.