Autism : clinical and neurobiological features early diagnosis treatment and some current developments Invited Author

Year 2010, Volume: 45 Issue: 12, 1 - 8, 01.06.2010

Barış Korkmaz

Abstract

Aim: The aim of this study is to review the studies about clinical and neurobiological features early diagnosis and treatment of autism nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; Material and Method: nbsp; A computerized literature search was conducted using PubMed to retrieve studies about clinical and neurobiological features early diagnosis and treatment of autism in addition to many references given to the textbooks Results: Autism is a neurobiological syndrome which has many subtypes through different mechanisms The severity and the profile of clinical presentation depend on the degree and pervasiveness of involvement of overlapping neuroanatomical circuits Among the clinical signs are impairment in social interaction and communication and restricted repetitive and stereotyped patterns of behavior interests and activities sensory and behavioral disturbances Conclusions: There is no cure for autism and it is a lifelong disorder Early diagnosis and beginning of early and appropriate educational intervention may improve adaptive skills Turk Arch Ped 2010; 45: 80th Year: 37 44 Key words: Autism clinical features early diagnosis neurobiological features treatment nbsp;

Keywords

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Otizm: Klinik ve nörobiyolojik özellikleri erken tanı tedavi ve bazı güncel gelişmeler Çağrılı Yazar

Abstract

Amaç: Bu çalışmanın amacı otizmin klinik ve nörobiyolojik özellikleri erken tanısı ve tedavisi ile ilgili yapılan çalışmaların gözden geçirilmesidir nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; nbsp; Gereç ve Yöntem: PubMed arama motoru kullanılarak otizmin klinik ve nörobiyolojik özellikleri erken tanısı ve tedavisi ile ilgili geçmişte yapılan çalışmalar gözden geçirilmiştir nbsp; Ayrıca konuyla ilgili kitap bölümleri de çalışmaya dahil edilmiştir nbsp; Bulgular: Otizm nörobiyolojik bir sendrom olup farklı mekanizmalar üstünden birçok farklı alt tipi olan bir hastalıktır Genetik temelde ama çevresel koşullardan da etkilenen nöroanatomik devrelerin tutulma yaygınlığına ve derecesine bağlı olarak klinik belirtiler ortaya çıkar Klinik özellikler arasında toplumsal etkileşimde ve iletişimde bozulma ve davranış ilgi ve etkinliklerde sınırlı basmakalıp ve yineleyici örüntünün olması duyu ve davranış sorunları vardır nbsp; nbsp; Çıkarımlar: Otizmin kesin bir tedavisi yoktur ve yaşam boyu süren bir hastalıktır Erken tanı ile erken bir uygun eğitimin başlaması uyum becerilerini oldukça artırabilir Türk Ped Arş 2010; 45: 80 Yıl: 37 44 Anahtar sözcükler: Erken tanı klinik özellikler nörobiyolojik özellikler otizm tedavi nbsp;

Keywords

Erken tanı, klinik özellikler, nörobiyolojik özellikler, otizm, tedavi

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