Abstract
Glucose 6 phosphate dehydrogenase G6PD is the first enzyme of the pentose phosphate pathway providing reducing power to all cells in the form of reduced form of nicotinamide adenine dinucleotide phosphate G6PD deficiency is the most common human enzyme defect being present in more than 400 million people worldwide G6PD deficiency is an X linked hereditary genetic defect caused by mutations in the G6PD gene Clinical presentations include acute hemolytic anemia chronic hemolytic anemia neonatal jaundice and favism which is usually triggered by an exogenous agent Turk Arch Ped 2009; 44 Suppl: 35 8 Key words: Diagnosis glucose 6 phosphate dehydrogenase hemolytic anemia childhood treatment
Keywords
References
- Luzzatto L, Poggi V. Glucose-6-phosphate deficiency. In: Or- kin SH, Nathan D, Ginsburg D, Look AT, Fisher DE, Lux SE (eds). Hematology of Infancy and Childhood. 7thedition. Phila- delphia: WB Saunders Company, 2009: 883-907. 377
Abstract
Glükoz 6 fosfat dehidrogenaz nbsp; G6PD tüm hücrelere redüksiyon gücünü oluşturan redükte nikotin adenin dinükleotid fosfatı sağlayan pentoz fosfat yolunun ilk enzimidir G6PD eksikliği dünyada en sık rastlanan eritrosit enzim eksikliğidir ve 400 milyondan fazla insanı etkilemektedir nbsp; G6PD eksikliği X’e bağlı geçiş gösteren G6PD genindeki mutasyonlardan kaynaklanan bir hastalıktır Klinik bulgular ekzojen ajanlarla tetiklenen akut hemolitik anemi kronik hemolitik anemi yenidoğan sarılığı ve favizmdir Türk Ped Arş 2009; 44 Özel Sayı: 35 8 Anahtar kelimeler: Glükoz 6 fosfat dehidrogenaz hemolitik anemi pediatrik tanı tedavi
References
- Luzzatto L, Poggi V. Glucose-6-phosphate deficiency. In: Or- kin SH, Nathan D, Ginsburg D, Look AT, Fisher DE, Lux SE (eds). Hematology of Infancy and Childhood. 7thedition. Phila- delphia: WB Saunders Company, 2009: 883-907. 377
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Review |
| Authors | |
| Publication Date | June 1, 2009 |
| Published in Issue | Year 2009 Volume: 44 Issue: 11 |