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Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör

Year 2008, Volume: 43 Issue: 2, 36 - 39, 01.06.2008

Abstract

Beta laktamlar bulundukları zamandan beri genel pediatri uygulamasında yaygın olarak kullanılmışlardır Fakat beta laktamların yol açtığı alerjik tepkiler ilaçlarla oluşan immünolojik tepkimelerin en sık sebebi olup bu ilaçların kullanılması gerektiğinde hem doktorlarda hem de ailelerde kaygıya yol açmaktadır Maalesef bu tepkimeler beta laktam antibiyotikleri oluşturan tüm ilaçlarla; penisilinler sefalosporinler aztreonam ve karbapenemler hepsi ile oluşabilir Ailelerin ve doktorların penisilin alerjisinden kaynaklanan kaygıları beta laktam antibiyotikler için gerçekten gerekli olsa da günlük uygulamalarda kullanımını kısıtlamakta ve böylece arzu edilmeyen veya vankomisin gibi daha pahalı antibiyotiklerin kullanımına yol açmaktadır Bütün bu sebeplerden dolayı bütün doktorların özellikle çocuk doktorlarının beta laktam alerjisini her yönüyle doğru bilmeleri gereklidir Türk Ped Arş 2008; 43: 36 9 Anahtar kelimeler: Anafilaksi beta laktam antibiyotikler penisilin

References

  • Solensky R. Hypersensitivity reactions to beta-lactam antibio- tics. Clin Rev Allergy Immunol 2003; 24: 201–19.
  • Sogn DD, Evans R, Shepherd GM, et al. Results of the National Institute of Allergy and Infectious Diseases Collaborative Clini- cal Trial to test the predictive value of skin testing with major and minor penicillin derivatives in hospitalized adults. Arch In- tern Med 1992; 152: 1025-32.
  • Parker CW, deWeck AL, Kern M, et al. The preparation and so- me properties of penicillenic acid derivatives relevant to penicil- lin hypersensitivity. J Exp Med 1962; 115: 803–19.
  • Levine BB, Redmond AP. Minor haptenic determinant–specific reagins of penicillin hypersensitivity in man. Int Arch Allergy Appl Immunol 1969; 35: 445–55.
  • Solensky R. Drug hypersensitivity. Med Clin N Am 2006: 90; 233-60.
  • Idsoe O, Guthe T, Wilcox RR, et al. Nature and extent of peni- cilin side-reactions, with particular reference to fatalities from anaphylactic shock. Bull World Health Organ 1968; 38: 158-88.
  • Empedrad R, Darter AL, Earl HS, Gruchalla RS. Nonirritating in- tradermal skin test concentrations for commonly prescribed antibiotics. J Allergy Clin Immunol 2003; 112: 629-30.
  • Bernstein IL, Gruchalla RS, Lee RE, et al. Disease management of drug hypersensitivity: a practice parameter. Ann Allergy Asthma Immunol 1999; 83: 665–700.
  • Girard GP, Common antigenic determinants of penicillin G, am- picillin, and the cephalosporins demonstrated in men. Int Arch Allergy 1968; 33: 428–38.
  • Assem E, Vickers MR. Tests for penicillin allergy in man, II: the immunological cross-reaction between penicillins and cepha- losporins: J Infect Dis 1978; 137: S74–9.
  • Levine BB. Antigenicity and cross-reactivity of penicillins and cephalosporins. J Infect Dis 1973; 128: S364–6.
  • Daulat SB, Solensky R, Earl HS, et al. Safety of cephalosporin administration to patients with histories of penicillin allergy. J Allergy Clin Immunol 2004; 113: 1220–2.
  • Miranda A, Blanca M, Vega JM, et al. Cross-reactivity between a penicillin and a cephalosporin with the same side chain. J Al- lergy Clin Immunol 1996; 98: 671–7.
  • Kelkar PS, Li JT. Cephalosporin allergy, N Engl J Med 2001; 345: 804–9.
  • Novalbos J, Sastre J, Cuesta M, et al. Lack of allergic cross-re- activity to cephalosporins among patients allergic to penicillins. Clin Exp Allergy 2001; 31: 438–43.
  • Adkinson NF, Saxon A, Spence MR, Swabb EA. Cross-allerge- nicity and immunogenicity of aztreonam. Rev Infect Dis 1985; 4: S613-21.
  • Saxon A, Hassner A, Swabb EA, et al. Lack of cross-reactivity between aztreonam, a monobactam antibiotic, and penicillin in penicillin-allergic subjects. J Infect Dis 1984; 149: 16–22.
  • Saxon A, Swabb EA, Adkinson NF. Investigation into the immu- nologic cross-reactivity of aztreonam with other beta-lactam antibiotics. Am J Med 1985; 78:19–26.
  • Perez Pimiento A, Gomez Martinez M, Minguez Mena A, et al. Aztreonam and ceftazidime: evidence of in vivo cross-allerge- nicity. Allergy 1997; 53: 624–5.
  • Vega JM, Blanca M, Garcia JJ, et al. Tolerance to aztreonam in patients allergic to betalactam antibiotics. Allergy 1991; 46:196–202.
  • Prescott WA, DePestel DD, Ellis JJ, et al. Incidence of carbape- nem-associated allergic-type reactions among patients with versus patients without a reported penicillin allergy. Clin Infect Dis 2004; 38: 1102–7.
  • TTüürrkk PPeedd AArrşş 22000088;; 4433:: 3366--99
  • TTuurrkk AArrcchh PPeedd 22000088;; 4433:: 3366--99
  • Penisilin, beta-laktam alerjileri

Current opinions on penicilin and other beta lactam antibiotic allergies Invited Editor

Year 2008, Volume: 43 Issue: 2, 36 - 39, 01.06.2008

Abstract

Beta lactam antibiotics have been commonly used in general pediatrics practice since their inventions But allergic reactions to beta lactams represent the most frequent cause of immunological drug reactions and lead to concerns both in doctors and parents when they are used Unfortunately these reactions may be induced by all beta lactams available including penicillins cephalosporins aztreonam and carbapenems Parents’ and clinicians’ concerns about penicillin allergy constrains beta lactam antibiotic usage in daily practice and therefore increase undesirable and more expensive antibiotic use such as vancomycin Because of these reasons all physicians especially pediatricians should know all aspects of beta lactam allergies Turk Arch Ped 2008; 43: 36 9 Key words: Anaphilaxy beta lactam antibiotic penicillin

References

  • Solensky R. Hypersensitivity reactions to beta-lactam antibio- tics. Clin Rev Allergy Immunol 2003; 24: 201–19.
  • Sogn DD, Evans R, Shepherd GM, et al. Results of the National Institute of Allergy and Infectious Diseases Collaborative Clini- cal Trial to test the predictive value of skin testing with major and minor penicillin derivatives in hospitalized adults. Arch In- tern Med 1992; 152: 1025-32.
  • Parker CW, deWeck AL, Kern M, et al. The preparation and so- me properties of penicillenic acid derivatives relevant to penicil- lin hypersensitivity. J Exp Med 1962; 115: 803–19.
  • Levine BB, Redmond AP. Minor haptenic determinant–specific reagins of penicillin hypersensitivity in man. Int Arch Allergy Appl Immunol 1969; 35: 445–55.
  • Solensky R. Drug hypersensitivity. Med Clin N Am 2006: 90; 233-60.
  • Idsoe O, Guthe T, Wilcox RR, et al. Nature and extent of peni- cilin side-reactions, with particular reference to fatalities from anaphylactic shock. Bull World Health Organ 1968; 38: 158-88.
  • Empedrad R, Darter AL, Earl HS, Gruchalla RS. Nonirritating in- tradermal skin test concentrations for commonly prescribed antibiotics. J Allergy Clin Immunol 2003; 112: 629-30.
  • Bernstein IL, Gruchalla RS, Lee RE, et al. Disease management of drug hypersensitivity: a practice parameter. Ann Allergy Asthma Immunol 1999; 83: 665–700.
  • Girard GP, Common antigenic determinants of penicillin G, am- picillin, and the cephalosporins demonstrated in men. Int Arch Allergy 1968; 33: 428–38.
  • Assem E, Vickers MR. Tests for penicillin allergy in man, II: the immunological cross-reaction between penicillins and cepha- losporins: J Infect Dis 1978; 137: S74–9.
  • Levine BB. Antigenicity and cross-reactivity of penicillins and cephalosporins. J Infect Dis 1973; 128: S364–6.
  • Daulat SB, Solensky R, Earl HS, et al. Safety of cephalosporin administration to patients with histories of penicillin allergy. J Allergy Clin Immunol 2004; 113: 1220–2.
  • Miranda A, Blanca M, Vega JM, et al. Cross-reactivity between a penicillin and a cephalosporin with the same side chain. J Al- lergy Clin Immunol 1996; 98: 671–7.
  • Kelkar PS, Li JT. Cephalosporin allergy, N Engl J Med 2001; 345: 804–9.
  • Novalbos J, Sastre J, Cuesta M, et al. Lack of allergic cross-re- activity to cephalosporins among patients allergic to penicillins. Clin Exp Allergy 2001; 31: 438–43.
  • Adkinson NF, Saxon A, Spence MR, Swabb EA. Cross-allerge- nicity and immunogenicity of aztreonam. Rev Infect Dis 1985; 4: S613-21.
  • Saxon A, Hassner A, Swabb EA, et al. Lack of cross-reactivity between aztreonam, a monobactam antibiotic, and penicillin in penicillin-allergic subjects. J Infect Dis 1984; 149: 16–22.
  • Saxon A, Swabb EA, Adkinson NF. Investigation into the immu- nologic cross-reactivity of aztreonam with other beta-lactam antibiotics. Am J Med 1985; 78:19–26.
  • Perez Pimiento A, Gomez Martinez M, Minguez Mena A, et al. Aztreonam and ceftazidime: evidence of in vivo cross-allerge- nicity. Allergy 1997; 53: 624–5.
  • Vega JM, Blanca M, Garcia JJ, et al. Tolerance to aztreonam in patients allergic to betalactam antibiotics. Allergy 1991; 46:196–202.
  • Prescott WA, DePestel DD, Ellis JJ, et al. Incidence of carbape- nem-associated allergic-type reactions among patients with versus patients without a reported penicillin allergy. Clin Infect Dis 2004; 38: 1102–7.
  • TTüürrkk PPeedd AArrşş 22000088;; 4433:: 3366--99
  • TTuurrkk AArrcchh PPeedd 22000088;; 4433:: 3366--99
  • Penisilin, beta-laktam alerjileri
There are 24 citations in total.

Details

Primary Language Turkish
Journal Section When the Turkish word exists
Authors

Feyzullah Çetinkaya This is me

Publication Date June 1, 2008
Published in Issue Year 2008 Volume: 43 Issue: 2

Cite

APA Çetinkaya, F. (2008). Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör. Türk Pediatri Arşivi, 43(2), 36-39.
AMA Çetinkaya F. Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör. Türk Pediatri Arşivi. June 2008;43(2):36-39.
Chicago Çetinkaya, Feyzullah. “Penisilin Ve diğer Beta Laktam Antibiyotik Alerjilerinde Son görüşler Çağrılı Editör”. Türk Pediatri Arşivi 43, no. 2 (June 2008): 36-39.
EndNote Çetinkaya F (June 1, 2008) Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör. Türk Pediatri Arşivi 43 2 36–39.
IEEE F. Çetinkaya, “Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör”, Türk Pediatri Arşivi, vol. 43, no. 2, pp. 36–39, 2008.
ISNAD Çetinkaya, Feyzullah. “Penisilin Ve diğer Beta Laktam Antibiyotik Alerjilerinde Son görüşler Çağrılı Editör”. Türk Pediatri Arşivi 43/2 (June 2008), 36-39.
JAMA Çetinkaya F. Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör. Türk Pediatri Arşivi. 2008;43:36–39.
MLA Çetinkaya, Feyzullah. “Penisilin Ve diğer Beta Laktam Antibiyotik Alerjilerinde Son görüşler Çağrılı Editör”. Türk Pediatri Arşivi, vol. 43, no. 2, 2008, pp. 36-39.
Vancouver Çetinkaya F. Penisilin ve diğer beta laktam antibiyotik alerjilerinde son görüşler Çağrılı Editör. Türk Pediatri Arşivi. 2008;43(2):36-9.