One hundred patients 41 females and 59 males with viral hepatitis and 25 healthy children 8 females and 17 males aged 2 13 years were included in this study In patients with viral hepatitis serum mucoprotein levels were 59 5±12 8 mg dl on admission 88 3±13 3 mg dl 20 days later and 99 7±12 4 mg dl 3 months later; HDL cholesterol levels were 28 7± 3 79 mg dl on admission 35 92±4 51 mg dl 20 days later and 40 23±4 75 mg dl 3 months later In healthy children serum mucoprotein and HDL cholesterol levels were 105 4±8 6 mg dl and 46 62±3 85 mg dl respectively Serum mucoprotein and HDL cholesterol values in patients with viral hepatitis on admission were lower than those of healthy children p lt;0 001 There were negative correlations in serum mucoprotein ALT serum mucoprotein AST HDL cholesterol ALT and HDL cholesterol AST values in patients with viral hepatitis We concluded that serum mucoprotein and HDL cholesterol may be of diagnostic and prognostic value as well as serum aminotransferases for the diagnosis and prognosis of viral hepatitis Key words: Serum Mucoprotein Hdl Cholesterol Viral Hepatitis
Çalışma 2 13 yaşları arasında 41 i kız 59 u erkek toplam 100 viral hepatitli çocuk ve 8 i kız 17 si erkek toplam 25 normal çocuk üzerinde yapıldı Akut viral hepatitli hastalarda serum mukoprotein ilk müracaatta 59 5±2 8 mg dl 20 gün sonra 88 3±13 3 mg dl ve 3 ay sonra 99 7±12 4 mg dl idi HDL kolesterol ilk müracaatta 28 7±3 79 mg dl 20 gün sonra 35 92±4 51 mg dl ve 3 ay sonra 40 23±4 75 mg dl idi Kontrol grubunda ise serum mukoprotein 105 4±8 6 mg dl HDL kolesterol 46 62±3 85 mg dl olarak bulundu Kontrol grubuyla kıyaslandığında viral hepatitli hastaların ilk müracaatlarındaki serum mukoprotein ve HDL kolesterol değerleri düşük bulundu p lt;0 001 Viral hepatitli hastalarda serum mukoprotein ve HDL kolesterol değerleri ile AST ve ALT değerleri arasında önemli negatif korelasyon vardı nbsp; Sonuçta viral hepatitin tanı ve prognozunda serum mukoprotein ve HDL kolesterolun aminotransferazların yanı sıra yararlı parametreler olabileceği kanaatine varıldı Anahtar kelimeler: Serum Mukoprotein Hdl Kolesterol Viral Hepatit
Primary Language | Turkish |
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Journal Section | When the Turkish word exists |
Authors | |
Publication Date | September 1, 1993 |
Published in Issue | Year 1993 Volume: 28 Issue: 3 |