Diagnosis and treatment of malignant lymphomas of parotid gland

Abstract

Objectives: This study aims to report surgical outcomes of primary parotid lymphomas and to discuss the histopathological subtypes, incidence rates, and clinical course. Patients and Methods: Between January 2002 and December 2014, eight patients 2 males, 6 females; man age 46.6 years; range 25 to 60 years who were diagnosed with primary parotid lymphoma and underwent parotidectomy were retrospectively analyzed. Demographic characteristics of the patients, histopathological subtypes, disease stage, and survival rates were recorded. Results: The ratio of the patients diagnosed with lymphoma was 2.82% among all patients, while 18.1% of the malignancies were lymphomas. Fine needle aspiration biopsy was non-diagnostic. CD20-positive low-grade B-cell lymphoma was the most common histopathological subtype in 37.5% of the patients. Conclusion: Based on our study results, the fine needle aspiration biopsy is not helpful in the diagnosis of the lymphomas of the parotid gland. Although rarely seen, lymphomas of the parotid gland should be considered in the differential diagnosis.

Keywords

• Parotid gland, primary parotid lymphoma, salivary gland neoplasm

Parotis bezi malign lenfomalarında tanı ve tedavi

Abstract

Amaç: Bu çalışmada primer parotis lenfomaların cerrahi sonuçları bildirildi ve histopatolojik alt tipleri, insidans oranları ve klinik seyri tartışıldı.Hastalar ve Yöntemler: Ocak 2002 - Aralık 2014 tarihleri arasında primer parotis lenfoma tanısı konulan ve parotidektomi yapılan sekiz hasta 2 erkek, 6 kadın; ort. yaş 46.6 yıl; dağılım 25-60 yıl retrospektif olarak incelendi. Hastaların demografik özellikleri, histopatolojik alttipleri, hastalık evresi ve sağkalım oranları kaydedildi.Bulgular: Lenfoma tanısı konulan hastaların tüm hastalar içerisindeki oranı %2.82 olup malign olguların %18.1’ini lenfomalar oluşturdu. İnce iğne aspirasyon biyopsisi tanısal değildi. CD20 pozitif düşük grade B hücreli lenfoma, hastaların %37.5’inde en sık görülen histopatolojik alt tip idi.Sonuç: Çalışma sonuçlarımıza göre, ince iğne aspirasyon biyopsisi parotis bezi lenfomalarının tanısında yardımcı değildir. Nadir görülmesine rağmen, parotis bezi lenfomaları ayırıcı tanıda göz önünde bulundurulmalıdır

Keywords

• Parotis bezi, primer parotis lenfoma, tükürük bezi neoplazisi

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