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Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi

Year 2002, Volume: 9 Issue: 1, 37 - 40, 03.01.2002

Abstract

Amaç: Tonsillektomi yapılan hastalarda lidokain hidroklörürün ameliyat sonrası dönemdeki ağrı üzerineolan etkinliğini arafltırmak. Hastalar ve Yöntemler: Çalıflmaya tonsillektomi yapılması planlanan 60 hasta alındı. Tüm hastalara lokal anestezi altında aynı cerrahlar tarafından tonsillektomi yapıldı. Ameliyat sonrasında hastalar rastgele 30’arlı iki gruba ayrıldı. Birinci gruptaki hastaların tonsiller fossasına,günlük toplam 4 mg/kg %10’luk lidokain HCl sprey eflitdozlarda, diğer grupta 2 ml %09 NaCl günde sekiz kezpüskürtüldü. Hastalar ameliyattan sonra birinci, üçüncüve yedinci günlerde kontrole çağrıldı. Kontroller sırasında ağrının değerlendirilmesi görsel analog skala ile yapıldı ve gruplar birbirleriyle karflılafltırıldı. Bulgular: Ameliyattan sonra ağrı açısından gruplararasında ve grupların kendi içlerinde günlere göreanlamlı farklılık saptandı p

References

  • Zalzal GH, Cotton RT. Pharyngitis and adenotonsillar disease. In: Cummings CW, Fredrickson JM, Harker LA, Schuller DE, editors. Otolaryngology head and neck surgery. 2nd ed. St. Louis: Mosby Year Book; 1993. p. 1180-98.
  • Robinson SR, Purdie GL. Reducing post-tonsillectomy pain with cryoanalgesia: a randomized contro l l e d trial. Laryngoscope 2000;110:1128-31.
  • Broadman LM, Patel RI, Feldman BA, Sellman GL, Milmoe G, Camilon F. The effects of peritonsillar infil- tration on the reduction of intraoperative blood loss and post-tonsillectomy pain in children. Laryngoscope 1989;99(6 Pt 1):578-81.
  • Schoem SR, Watkins GL, Kuhn JJ, Alburger JF, Kim KZ, Thompson DH. Control of early postoperative pain with bupivacaine in adult local tonsillectomy. Arch Otolaryngol Head Neck Surg 1993;119:292-3.
  • Wall PD. The prevention of postoperative pain. Pain 1988;33:289-90.
  • Susaman N, Karlıdağ T. Bupivakain HCl ve deksame- tazonun tonsillektomi veya adenotonsillektomi yapı- lan hastalarda iyileflme üzerine etkileri. KBB Klinikleri 2000:2:88-91.
  • F reeman SB, Markwell JK. Sucralfate in alleviating post-tonsillectomy pain. Laryngoscope 1992;102: 1 2 4 2 - 6 .
  • Kayaalp SO. Tıbbi Farmakoloji. 1. baskı. Ankara: Fer- yal Matbaacılık; 1990.
  • Kornblut AD. A traditional approach to surgery of the tonsils and adenoids. Otolaryngol Clin North Am 1987;20:349-63.
  • Goldsher M, Podoshin L, Fradis M, Malatskey S, Gerstel R, Vaida S, et al. Effects of peritonsillar infiltra- tion on post-tonsillectomy pain. A double-blind study. Ann Otol Rhinol Laryngol 1996;105:868-70.
  • Myatt HM, Myatt RA. The development of a paedi- atric quality of life questionnaire to measure post- operative pain following tonsillectomy. Int J Pediatr Otorhinolaryngol 1998;44:115-23.
  • Leach J, Manning S, Schaefer S. Comparison of two methods of tonsillectomy. Laryngoscope 1993; 1 0 3 : 6 1 9 - 2 2 .
  • Schoem SR, Watkins GL, Kuhn JJ, Thompson DH. Control of early postoperative pain with bupivacaine in pediatric tonsillectomy. Ear Nose Throat J 1993;72: 560-3.
  • Johansen M, Harbo G, Illum P. Preincisional infiltration with bupivacaine in tonsillectomy. Arch Otolaryngol Head Neck Surg 1996;122:261-3.
  • Jebeles JA, Reilly JS, Gutierrez JF, Bradley EL Jr, Kissin I. The effect of pre-incisional infiltration of tonsils with bupivacaine on the pain following tonsillectomy under general anesthesia. Pain 1991;47:305-8.
  • Tverskoy M, Cozacov C, Ayache M, Bradley EL Jr, Kissin I. Postoperative pain after inguinal herniorrha- phy with different types of anesthesia. Anesth Analg 1990;70:29-35.
  • Virtaniemi J, Kokki H, Nikanne E, Aho M. Ketoprofen and fentanyl for pain after uvulopalatopharyngoplas- ty and tonsillectomy. Laryngoscope 1999;109:1950-4.
  • Kitajiri S, Tabuchi K, Hiraumi H, Kaetsu H. Relief of post-tonsillectomy pain by release of lidocaine from fibrin glue. Laryngoscope 2001;111(4 Pt 1):642-4.
  • Bissonnette B. Lidocaine aerosol following tonsillecto- my in children. Can J Anaesth 1990;37:534-7. [Abstract]
  • Elhakim M, Abdel Hay H. Comparison of preopera- tive with postoperative topical lidocaine spray on pain after tonsillectomy. Acta Anaesthesiol Scand 1995;39: 1032-5. [Abstract]

The effect of lidocaine HCl aerosol on postoperative pain in tonsillectomy patients

Year 2002, Volume: 9 Issue: 1, 37 - 40, 03.01.2002

Abstract

Objectives: We evaluated the efficacy of lidocaine hydrochloride aerosol on postoperative pain relief in patients undergoing tonsillectomy.Patients and Methods: The study included 60patients 25 females, 35 males; mean age 25.43 years; range 16 to 35 years undergoing tonsillecto­ my. The procedure was performed by the same surgeons under local anesthesia. The patients were randomly divided into two groups to receive either lidocaine HCI n=30 or NaCI n=30 . A total of 4 mg/kg of 10% lidocaine HCI aerosol and 2 mİ of 0.9% NaCI were applied to the tonsillectomy fossa eight times daily, respectively. Evaluation of pain was made on the first, third, and seventh postopera­ tive days using a visual analogue scale.Results: Significant differences were found betvveen the groups on the first, third, and seventh postoperative days p<0.05 . İn each group, patient’s evaluation of pain differed significantly p<0.05 . The significance levels were higher for lidocaine on the first and third days.Conclusion: Our results suggest that lidocaine HCI aerosol exerts a therapeutic effect on postoperative pain control in tonsillectomy patients.

References

  • Zalzal GH, Cotton RT. Pharyngitis and adenotonsillar disease. In: Cummings CW, Fredrickson JM, Harker LA, Schuller DE, editors. Otolaryngology head and neck surgery. 2nd ed. St. Louis: Mosby Year Book; 1993. p. 1180-98.
  • Robinson SR, Purdie GL. Reducing post-tonsillectomy pain with cryoanalgesia: a randomized contro l l e d trial. Laryngoscope 2000;110:1128-31.
  • Broadman LM, Patel RI, Feldman BA, Sellman GL, Milmoe G, Camilon F. The effects of peritonsillar infil- tration on the reduction of intraoperative blood loss and post-tonsillectomy pain in children. Laryngoscope 1989;99(6 Pt 1):578-81.
  • Schoem SR, Watkins GL, Kuhn JJ, Alburger JF, Kim KZ, Thompson DH. Control of early postoperative pain with bupivacaine in adult local tonsillectomy. Arch Otolaryngol Head Neck Surg 1993;119:292-3.
  • Wall PD. The prevention of postoperative pain. Pain 1988;33:289-90.
  • Susaman N, Karlıdağ T. Bupivakain HCl ve deksame- tazonun tonsillektomi veya adenotonsillektomi yapı- lan hastalarda iyileflme üzerine etkileri. KBB Klinikleri 2000:2:88-91.
  • F reeman SB, Markwell JK. Sucralfate in alleviating post-tonsillectomy pain. Laryngoscope 1992;102: 1 2 4 2 - 6 .
  • Kayaalp SO. Tıbbi Farmakoloji. 1. baskı. Ankara: Fer- yal Matbaacılık; 1990.
  • Kornblut AD. A traditional approach to surgery of the tonsils and adenoids. Otolaryngol Clin North Am 1987;20:349-63.
  • Goldsher M, Podoshin L, Fradis M, Malatskey S, Gerstel R, Vaida S, et al. Effects of peritonsillar infiltra- tion on post-tonsillectomy pain. A double-blind study. Ann Otol Rhinol Laryngol 1996;105:868-70.
  • Myatt HM, Myatt RA. The development of a paedi- atric quality of life questionnaire to measure post- operative pain following tonsillectomy. Int J Pediatr Otorhinolaryngol 1998;44:115-23.
  • Leach J, Manning S, Schaefer S. Comparison of two methods of tonsillectomy. Laryngoscope 1993; 1 0 3 : 6 1 9 - 2 2 .
  • Schoem SR, Watkins GL, Kuhn JJ, Thompson DH. Control of early postoperative pain with bupivacaine in pediatric tonsillectomy. Ear Nose Throat J 1993;72: 560-3.
  • Johansen M, Harbo G, Illum P. Preincisional infiltration with bupivacaine in tonsillectomy. Arch Otolaryngol Head Neck Surg 1996;122:261-3.
  • Jebeles JA, Reilly JS, Gutierrez JF, Bradley EL Jr, Kissin I. The effect of pre-incisional infiltration of tonsils with bupivacaine on the pain following tonsillectomy under general anesthesia. Pain 1991;47:305-8.
  • Tverskoy M, Cozacov C, Ayache M, Bradley EL Jr, Kissin I. Postoperative pain after inguinal herniorrha- phy with different types of anesthesia. Anesth Analg 1990;70:29-35.
  • Virtaniemi J, Kokki H, Nikanne E, Aho M. Ketoprofen and fentanyl for pain after uvulopalatopharyngoplas- ty and tonsillectomy. Laryngoscope 1999;109:1950-4.
  • Kitajiri S, Tabuchi K, Hiraumi H, Kaetsu H. Relief of post-tonsillectomy pain by release of lidocaine from fibrin glue. Laryngoscope 2001;111(4 Pt 1):642-4.
  • Bissonnette B. Lidocaine aerosol following tonsillecto- my in children. Can J Anaesth 1990;37:534-7. [Abstract]
  • Elhakim M, Abdel Hay H. Comparison of preopera- tive with postoperative topical lidocaine spray on pain after tonsillectomy. Acta Anaesthesiol Scand 1995;39: 1032-5. [Abstract]
There are 20 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

İrfan Kaygusuz This is me

Nihat Susaman This is me

Publication Date January 3, 2002
Published in Issue Year 2002 Volume: 9 Issue: 1

Cite

APA Kaygusuz, İ., & Susaman, N. (2002). Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi. The Turkish Journal of Ear Nose and Throat, 9(1), 37-40.
AMA Kaygusuz İ, Susaman N. Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi. Tr-ENT. January 2002;9(1):37-40.
Chicago Kaygusuz, İrfan, and Nihat Susaman. “Tonsillektomi yapılan Hastalarda Lidokain HC1 Spreyin Ameliyat Sonrası ağrı üzerine Etkisi”. The Turkish Journal of Ear Nose and Throat 9, no. 1 (January 2002): 37-40.
EndNote Kaygusuz İ, Susaman N (January 1, 2002) Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi. The Turkish Journal of Ear Nose and Throat 9 1 37–40.
IEEE İ. Kaygusuz and N. Susaman, “Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi”, Tr-ENT, vol. 9, no. 1, pp. 37–40, 2002.
ISNAD Kaygusuz, İrfan - Susaman, Nihat. “Tonsillektomi yapılan Hastalarda Lidokain HC1 Spreyin Ameliyat Sonrası ağrı üzerine Etkisi”. The Turkish Journal of Ear Nose and Throat 9/1 (January 2002), 37-40.
JAMA Kaygusuz İ, Susaman N. Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi. Tr-ENT. 2002;9:37–40.
MLA Kaygusuz, İrfan and Nihat Susaman. “Tonsillektomi yapılan Hastalarda Lidokain HC1 Spreyin Ameliyat Sonrası ağrı üzerine Etkisi”. The Turkish Journal of Ear Nose and Throat, vol. 9, no. 1, 2002, pp. 37-40.
Vancouver Kaygusuz İ, Susaman N. Tonsillektomi yapılan hastalarda lidokain HC1 spreyin ameliyat sonrası ağrı üzerine etkisi. Tr-ENT. 2002;9(1):37-40.