Comparison of nasal smear eosinophilia with skin prick test

Year 2006, Volume: 16 Issue: 2, 60 - 63, 20.03.2006

Sedat Aydın Arif Şanlı Günay Ateş Mehmet Eken Özlem Çelebi

Abstract

Objectives: The aim of this study was to compare the usefulness of nasal smear eosinophilia with skin prick test for the diagnosis of allergic rhinitis and to deter- mine the degree of correlation between the tests.Patients and Methods: Forty-one patients 16 males, 25 females; mean age 35.17; range 14 to 56 years with a clinical history suggestive of nasal allergy and fifteen Controls 7 males, 8 females; mean age 27.6; range 16 to 40 years without any history of allergy were enrolled in this study. Skin sensitivity tests were applied in both groups. Nasal smear was examined by light microscopy.Results: A positive skin test reaction was demon- strated in 73.2% of the study group and 20% of the Controls whereas 73.2% of the patients and 13.3% of the Controls demonstrated significant nasal smear eosinophilia. There was 25.5% correlation between the skin prick test and nasal smear eosinophilia, although this was not statistically sig­ nificant.Conclusion: Both the skin prick test and the nasal smear eosinophilia showed correlation with the clin­ ical history but there was no statistically significant correlation between the two tests.

Keywords

Allergic rhinitis, skin-prick test, nasal smear, eosinophilia

Alerjik rinitli hastalarda alerjik deri pozitifliği ile nazal smear'deki eozinofilinin karşılaştırılması

Abstract

Amaç: Alerjik rinit tanısında kullanılan deri testi ile nazal smear’de saptanan eozinofilinin kullanılabilirli­ ği ve bu iki test arasındaki ilişkinin derecesi karşılaştırıldı.Hastalar ve Yöntemler: Çalışmaya klinik öyküyle nazal alerjiden şüphe edilen 41 hasta 16 erkek, 25 kadın; ort. yaş 35.17; dağılım 14-56 ve öyküsünde alerjiyle ilgili herhangi bir şikayeti olmayan 15 gönül­ lü 7 erkek, 8 kadın; ort. yaş 27.6; dağılım 16-40 alındı. Her iki gruba alerjik deri testi uygulandı. Na­ zal smearler alınıp ışık mikroskobu altında değerlen­ dirildi.Bulgular: Çalışma grubundaki hastalarda, deri tes­tinin pozitiflik oranı %73.2 iken kontrol grubunda bu oran %20 idi. Bununla birlikte hastaların %73.2 ve kontrol grubunun %13.3’ünde nazal smearde eozi- nofili saptandı. Her ne kadar alerjik deri testi ile na­zal smear arasında %25.5 oranında bir ilişki olsada alerjik deri testi ile nazal smear’de saptanan eozino- fili arasında istatistiksel olarak anlamlı bir ilişki yoktu.Sonuç: Alerjik deri testi ve nazal smearde saptanan eozinofili, klinik öykü ile ilişki göstermekle birlikte, bu iki test arasında istatistiksel olarak anlamlı bir ilişki bulunamadı.

Keywords

Alerjik rinit, alerjik deri testi, nazal smear, eozinofili

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