Microorganisms isolated from middle ear cultures and their antibacterial susceptibility in patients with chronic suppurative otitis media

Year 2006, Volume: 16 Issue: 4, 164 - 168, 27.08.2006

H. Cem Gül Ali Kurnaz Vedat Turhan Mustafa Oral Öncül Alahattin Pahsa

Abstract

Objectives: This study sought to determine causative microorganisms of chronic suppurative otitis media and their antibacterial susceptibility.Patients and Methods: Bacteriologic results of middle ear swabs, agent microorganisms, and their suscepti­ bility to antibiotics were evaluated in 70 patients 65 males, 5 females; mean age 21.1±1.3 years; range 19 to 25 years with chronic suppurative otitis media.Results: No bacteria were isolated in 14% of the patients. Of 60 patients in whom bacteria were isolat­ ed, the most common bacteria was Pseudomonas aeruginosa 23% , followed by Staphylococcus aureus 18% , and Proteus spp. 17% . P. aeruginosa strains were susceptible to ceftazidime and imipenem 100% , ciprofloxacin 92% , and amikacin and gentamycin 85% ; S. aureus strains were susceptible to methicillin and vancomycin 100% , ciprofloxacin 91% , sulbac- tam-ampicillin 73% , and gentamycin and trimetho- prim-sulfamethoxazole 63% . Proteus strains were susceptible to ciprofloxacin 100% , ceftazidime 90% , and imipenem and gentamycin 70% .Conclusion: Appropriate knowledge of antibacterial susceptibility of microorganisms will contribute to rational antibiotic usage and the success of treat- ment for chronic suppurative otitis media.

Keywords

Anti-bacterial agents, microbial sensitivity tests, otitis media, suppurative/microbiology/drug therapy

Kronik süpüratif otitis medialı hastalarda orta kulak kültürlerinde üreyen mikroorganizmalar ve antibiyotik duyarlılıkları

Abstract

Amaç: Bu çalışmada kronik süpüratif otitis mediayaneden olan mikroorganizmalar ve antibiyotik duyarlılıklarının belirlenmesi amaçlandı.Hastalar ve Yöntemler: Kronik süpüratif otitis media tanısı konan 70 hastanın orta kulak kültürlerininbakteriyolojik sonuçları, etken mikroorganizmalar vebunların antibiyotik duyarlılıkları değerlendirildi.Bulgular: Çalışmaya alınan hastaların %14’ünde bakteri izole edilemedi. Altmış izolatta en sık karşılaşılanbakteri %23 oranıyla Pseudomonas aeruginosa idi.Bunu %18 ile Staphylococcus aureus ve %17 ileProteus türleri izlemekteydi. P. aeruginosa suşlarınıntamamı seftazidim ve imipeneme, %92’si siprofloksasine, %85’i amikasin ve gentamisine duyarlı bulundu. S. aureus suşlarının tamamı metisilin ve vankomisine, %91’i siprofloksasine, %73’ü sulbaktamampisiline, %63’ü gentamisin ve trimetoprim-sulfometoksazola duyarlıydı. Proteus türlerinin hepsi siprofloksasine, %90’ı seftazidime, %70’i imipenem vegentamisine duyarlı idi.Sonuç: Kronik süpüratif otitis media tedavisinde, mikroorganizma duyarlılığının önceden bilinmesi rasyonelantibiyotik kullanımına ve tedavi başarısına katkıdabulunacaktır

Keywords

Antibakteriyel ajan, mikrobiyal duyarlılık testi, otitis media, süpüratif/mikrobiyoloji/ilaç tedavisi

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