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Thyroid masses: an analysis of 131 cases

Year 2008, Volume: 18 Issue: 5, 289 - 293, 10.10.2008

Abstract

Objectives: We retrospectively analyzed patients undergoing surgery for thyroid masses. Patients and Methods: A total of 131 patients 80 males, 51 females who underwent surgery for thyroid masses between 1993 and 2007 were evaluated with respect to clinical findings, histopathologic diagnoses, and treatment modalities. Results: The thyroid masses were found benign in 48.1% and malignant in 51.9% of the patients. Fortyone females 65% and 22 males 35% had benign thyroid masses, while 39 females 57% and 29 males 43% had malignant thyroid masses. According to histopathologic results, the most common benign and malignant diagnoses were multinodular goiter n=57, 43.5% and papillary carcinoma n=50, 38.2% , respectively. The mean duration of complaints was 58 months for benign and 30 months for malignant tumors. Conclusion: Thyroid operations are becoming increasingly common in otorhinolaryngologic surgical procedures.

References

  • Güney E. Tiroid ve paratiroid neoplazmları. In: Çelik O, editör. Kulak burun boğaz hastalıkları ve baş boyun cerrahisi. İstanbul: Turgut Yayıncılık; 2002. s. 750-800.
  • Tan GH, Gharib H, Reading CC. Solitary thyroid nod- ule. Comparison between palpation and ultrasonogra- phy. Arch Intern Med 1995;155:2418-23.
  • Day TA, Chu A, Hoang KG. Multinodular goiter. Otolaryngol Clin North Am 2003;36:35-54.
  • Hedinger C, Williams ED, Sobin LH. Histological typ- ing of thyroid tumours. In: International Histological Classification of Tumors. World Health Organization. 2nd ed. Berlin: Springer; 1988. p. 3-4.
  • Greene FL, Page DL, Fleming ID, Fritz A, Balch CM, Haller DG, Morrow M, editors. AJCC cancer staging manual. 6th ed. New York: Springer; 2002.
  • Knudsen N, Perrild H, Christiansen E, Rasmussen S, Dige-Petersen H, Jorgensen T. Thyroid structure and size and two-year follow-up of solitary cold thyroid nodules in an unselected population with borderline iodine deficiency. Eur J Endocrinol 2000;142:224-30.
  • Dumont JE, Lamy F, Roger P, Maenhaut C. Physiological and pathological regulation of thyroid cell prolifera- tion and differentiation by thyrotropin and other fac- tors. Physiol Rev 1992;72:667-97.
  • Peter HJ, Studer H, Groscurth P. Autonomous growth, but not autonomous function, in embryonic human thyroids: a clue to understanding autonomous goiter growth? J Clin Endocrinol Metab 1988;66:968-73.
  • Koh KB, Chang KW. Carcinoma in multinodular goi- tre. Br J Surg 1992;79:266-7.
  • Mathai V, Idikula J, Fenn AS, Nair A. Do long-standing nodular goitres result in malignancies? Aust N Z J Surg 1994;64:180-2.
  • Beahrs OH. Workshop on late effects of irradiation to the head and neck in infancy and childhood. Radiology 1976;120:733-4.
  • Robbins J, Merino MJ, Boice JD Jr, Ron E, Ain KB, Alexander HR, et al. Thyroid cancer: a lethal endocrine neoplasm. Ann Intern Med 1991;115:133-47.
  • Shore RE. Issues and epidemiological evidence regard- ing radiation-induced thyroid cancer. Radiat Res 1992; 131:98-111.
  • Ron E, Lubin JH, Shore RE, Mabuchi K, Modan B, Pottern LM, et al. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res 1995;141:259-77.
  • Franceschi S, Fassina A, Talamini R, Mazzolini A, Vianello S, Bidoli E, et al. Risk factors for thyroid can- cer in northern Italy. Int J Epidemiol 1989;18:578-84.
  • Franceschi S, Talamini R, Fassina A, Bidoli E. Diet and epithelial cancer of the thyroid gland. Tumori 1990;76:331-8.
  • dos Santos Silva I, Swerdlow AJ. Sex differences in the risks of hormone-dependent cancers. Am J Epidemiol 1993;138:10-28.

Tiroid kitleleri: 131 olgunun değerlendirilmesi

Year 2008, Volume: 18 Issue: 5, 289 - 293, 10.10.2008

Abstract

Amaç: Tiroid kitlesi tanısıyla ameliyat edilen hastalar geriye dönük olarak incelendi.Hastalar ve Yöntemler: 1993-2007 yılları arasında tiroid kitlesi öntanısıyla ameliyat edilen 131 hastanın 80 erkek, 51 kadın klinik bulguları, histopatolojik sonuçları ve uygulanan tedavi yöntemleri değerlendirildi.Bulgular: Hastaların %48.1’inde benign, %51.9’unda malign tiroid kitlesi saptandı. Cinsiyet dağılımı benign tümörlü grupta 41 kadın %65 , 22 erkek %35 ; malign tümörlü grupta 39 kadın %57 , 29 erkek %43 şeklindeydi. Histopatolojik tanılara göre en sık rastlanan benign tiroid kitlesi multinodüler guatr n=57, %43.5 , malign tümör ise papiller karsinom n=50, %38.2 idi. Benign tümörlü hastalarda şikayet süresi ortalama 58 ay, malign tümörlü hastalarda 30 ay bulundu.Sonuç: Tiroid ameliyatları kulak burun boğaz hastalıkları kliniğinde artarak uygulanan baş-boyun cerrahisi prosedürlerinden biri haline gelmiştir

References

  • Güney E. Tiroid ve paratiroid neoplazmları. In: Çelik O, editör. Kulak burun boğaz hastalıkları ve baş boyun cerrahisi. İstanbul: Turgut Yayıncılık; 2002. s. 750-800.
  • Tan GH, Gharib H, Reading CC. Solitary thyroid nod- ule. Comparison between palpation and ultrasonogra- phy. Arch Intern Med 1995;155:2418-23.
  • Day TA, Chu A, Hoang KG. Multinodular goiter. Otolaryngol Clin North Am 2003;36:35-54.
  • Hedinger C, Williams ED, Sobin LH. Histological typ- ing of thyroid tumours. In: International Histological Classification of Tumors. World Health Organization. 2nd ed. Berlin: Springer; 1988. p. 3-4.
  • Greene FL, Page DL, Fleming ID, Fritz A, Balch CM, Haller DG, Morrow M, editors. AJCC cancer staging manual. 6th ed. New York: Springer; 2002.
  • Knudsen N, Perrild H, Christiansen E, Rasmussen S, Dige-Petersen H, Jorgensen T. Thyroid structure and size and two-year follow-up of solitary cold thyroid nodules in an unselected population with borderline iodine deficiency. Eur J Endocrinol 2000;142:224-30.
  • Dumont JE, Lamy F, Roger P, Maenhaut C. Physiological and pathological regulation of thyroid cell prolifera- tion and differentiation by thyrotropin and other fac- tors. Physiol Rev 1992;72:667-97.
  • Peter HJ, Studer H, Groscurth P. Autonomous growth, but not autonomous function, in embryonic human thyroids: a clue to understanding autonomous goiter growth? J Clin Endocrinol Metab 1988;66:968-73.
  • Koh KB, Chang KW. Carcinoma in multinodular goi- tre. Br J Surg 1992;79:266-7.
  • Mathai V, Idikula J, Fenn AS, Nair A. Do long-standing nodular goitres result in malignancies? Aust N Z J Surg 1994;64:180-2.
  • Beahrs OH. Workshop on late effects of irradiation to the head and neck in infancy and childhood. Radiology 1976;120:733-4.
  • Robbins J, Merino MJ, Boice JD Jr, Ron E, Ain KB, Alexander HR, et al. Thyroid cancer: a lethal endocrine neoplasm. Ann Intern Med 1991;115:133-47.
  • Shore RE. Issues and epidemiological evidence regard- ing radiation-induced thyroid cancer. Radiat Res 1992; 131:98-111.
  • Ron E, Lubin JH, Shore RE, Mabuchi K, Modan B, Pottern LM, et al. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res 1995;141:259-77.
  • Franceschi S, Fassina A, Talamini R, Mazzolini A, Vianello S, Bidoli E, et al. Risk factors for thyroid can- cer in northern Italy. Int J Epidemiol 1989;18:578-84.
  • Franceschi S, Talamini R, Fassina A, Bidoli E. Diet and epithelial cancer of the thyroid gland. Tumori 1990;76:331-8.
  • dos Santos Silva I, Swerdlow AJ. Sex differences in the risks of hormone-dependent cancers. Am J Epidemiol 1993;138:10-28.
There are 17 citations in total.

Details

Primary Language Turkish
Journal Section Research Article
Authors

Sedat Çağlı This is me

İmdat Yüce This is me

Ali Bayram This is me

Ercihan Güney This is me

Publication Date October 10, 2008
Published in Issue Year 2008 Volume: 18 Issue: 5

Cite

APA Çağlı, S., Yüce, İ., Bayram, A., Güney, E. (2008). Tiroid kitleleri: 131 olgunun değerlendirilmesi. The Turkish Journal of Ear Nose and Throat, 18(5), 289-293.
AMA Çağlı S, Yüce İ, Bayram A, Güney E. Tiroid kitleleri: 131 olgunun değerlendirilmesi. Tr-ENT. October 2008;18(5):289-293.
Chicago Çağlı, Sedat, İmdat Yüce, Ali Bayram, and Ercihan Güney. “Tiroid Kitleleri: 131 Olgunun değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat 18, no. 5 (October 2008): 289-93.
EndNote Çağlı S, Yüce İ, Bayram A, Güney E (October 1, 2008) Tiroid kitleleri: 131 olgunun değerlendirilmesi. The Turkish Journal of Ear Nose and Throat 18 5 289–293.
IEEE S. Çağlı, İ. Yüce, A. Bayram, and E. Güney, “Tiroid kitleleri: 131 olgunun değerlendirilmesi”, Tr-ENT, vol. 18, no. 5, pp. 289–293, 2008.
ISNAD Çağlı, Sedat et al. “Tiroid Kitleleri: 131 Olgunun değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat 18/5 (October 2008), 289-293.
JAMA Çağlı S, Yüce İ, Bayram A, Güney E. Tiroid kitleleri: 131 olgunun değerlendirilmesi. Tr-ENT. 2008;18:289–293.
MLA Çağlı, Sedat et al. “Tiroid Kitleleri: 131 Olgunun değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat, vol. 18, no. 5, 2008, pp. 289-93.
Vancouver Çağlı S, Yüce İ, Bayram A, Güney E. Tiroid kitleleri: 131 olgunun değerlendirilmesi. Tr-ENT. 2008;18(5):289-93.