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Microscopic guide to the middle ear anatomy in guinea pigs

Year 2009, Volume: 19 Issue: 2, 87 - 94, 12.03.2009

Abstract

Objectives: To reveal microscopic surgical anatomy of the middle ear in guinea pigs GPs . Materials and Methods: Twenty ears of GPs were dissected under dissection microscopy via inferior approach. By using digital equipment, the most suitable photograph was taken for each step. Differences and similarities between the ears of GPs and those of human beings are discussed to show the advantages and disadvantages of the GP ear for experimental studies. Results: Tympanic membrane of the GP merely consists of pars tensa and above this there is a bony segment called as supratympanic crest. There were two spaces called bulla and hypotympanium in the GP’s middle ear. Cochlea, which is normally found in the inner ear in humans, separates these two spaces. Upper part of this space which is called epitympanium is a slit like cavity having a bony complex called malleoincudal complex. Bulla, the largest cavity in the middle ear, is a hemispherical cavity having a smooth surface. It corresponds to hypotympanum and mesotympanum of human middle ear. Cochlea has 3.5 turns from basal turn to apical turn. While the oval window is placed vertically, the round window is placed horizontally. While the stapes is almost identical to that of the humans, there is a bony bridge between the crura of the stapes called crista stapedius. Stapes can not removed unless this bony bridge is taken. Conclusion: The middle ear in GP differs from the human middle ear in many aspects. Researchers who are planning to the study with this animal model should be aware of all these differences.

References

  • Asarch R, Abramson M, Litton WB. Surgical anatomy of the guinea pig ear. Ann Otol Rhinol Laryngol 1975;84:250-5.
  • Sehitoğlu MA, Uneri C, Celikoyar MM, Uneri A. Surgical anatomy of the guinea pig middle ear. Ear Nose Throat J 1990;69:91-7.
  • Goksu N, Haziroglu R, Kemaloglu Y, Karademir N, Bayramoglu I, Akyildiz N. Anatomy of the guinea pig temporal bone. Ann Otol Rhinol Laryngol 1992;101:699- 704.
  • Sichel JY, Plotnik M, Cherny L, Sohmer H, Elidan J. Surgical anatomy of the ear of the fat sand rat. J Otolaryngol 1999;28:217-22.
  • Judkins RF, Li H. Surgical anatomy of the rat middle ear. Otolaryngol Head Neck Surg 1997;117:438-47.
  • Browning GC, Granich MS. Surgical anatomy of the temporal bone in the chinchilla. Ann Otol Rhinol Laryngol 1978;87:875-82.
  • Preminger GM, Delvecchio FC, Birnbach JM. Digital image recording: an integral aspect of video endos- copy. Stud Health Technol Inform 1999;62:268-74.
  • Gürel Y, Bilgili A. Laboratuvar hayvanlarının aneste- zisi. Etlik Vet Mikrob Derg 2001;12:65-74.
  • Bojrab DI, Wiet RJ. Surgical anatomy of the temporal bone through dissection. In Glasscock ME, Shambaugh GE Jr, editors. Surgery of the ear. 4th ed. Philadelphia: W. B. Saunders Co; 1990. p. 579-618.
  • Kayhan FT, Algün Z. A histologic study on the tempo- ral bone of guinea pigs. Kulak Burun Bogaz Ihtis Derg 2003;10:51-7.
  • Sütbeyaz Y, Karaşen M. Guinea pig temporal kemik anatomisi. Kulak Burun Boğaz İhtisas Dergisi 1998; 5:173-7.
  • Adamczyk M, Appleton CM, Parell GJ, Antonelli PJ. Stapedectomy in the guinea pig. Otolaryngol Head Neck Surg 1999;121:581-4.
  • Wysocki J. Topographical anatomy of the guinea pig temporal bone. Hear Res 2005;199:103-10.
  • Amin S, Tucker AS. Joint formation in the middle ear: lessons from the mouse and guinea pig. Dev Dyn 2006;235:1326-33.

Kobaylarda orta kulak anatomisi için mikroskopik kılavuz

Year 2009, Volume: 19 Issue: 2, 87 - 94, 12.03.2009

Abstract

Amaç: Kobaylarda mikroskopik cerrahi yöntemi ile orta kulak anatomisi ortaya kondu.Gereç ve Yöntem: Yirmi kobay kulağı diseksiyon mikroskobu altında inferior yaklaşım kullanılarak diseke edildi. Dijital cihaz kullanılarak her aşama için en uygun fotoğraflar çekildi. Deneysel çalışmalar için kobay kulağının avantaj ve dezavantajlarını göstermek için kobay ve insan kulağı arasındaki farklılıklar ve benzerlikler ele alındı.Bulgular: Kobay timpanik membranı sadece pars tensadan ibaret olup yukarıda supratimpanik krest diye isimlendirilen kemik yapı bulunur. Kobay orta kulağında epitimpanum ve bulla diye iki boşluk bulunur. Bu iki yapıyı normalde insanlarda iç kulakta bulunan koklea ayırır. Üst kısımdaki boşluk epitimpanum olup içerisinde füzyon haline uğramış malleoincudal kompleks bulunur. Bulla en büyük boşluk olup yarım küre şeklinde ve düzgün yüzeylidir. İnsan kulağındaki mezotimpanum ve hipotimpanuma karşılık gelir. Koklea bazal kıvrımdan apikale kadar 3.5 tur döner. Oval pencere vertikal planda yerleşirken yuvarlak pencerenin yerleşimi horizontal plandadır. Stapes insanlardaki gibi şekle sahipken bacaklarının arasında krista stapedius olarak bilinen kemik köprü bulunur. Stapes bu kemik köprü çıkarılmadan kaldırılamaz.Sonuç: Kobay orta kulağı birçok bakımdan insan orta kulağından farklıdır. Bu hayvan modeli ile araştırma yapmayı planlayan araştırmacıların orta kulağa yönelik tüm bu farklılıkların farkında olmaları gerekmektedir

References

  • Asarch R, Abramson M, Litton WB. Surgical anatomy of the guinea pig ear. Ann Otol Rhinol Laryngol 1975;84:250-5.
  • Sehitoğlu MA, Uneri C, Celikoyar MM, Uneri A. Surgical anatomy of the guinea pig middle ear. Ear Nose Throat J 1990;69:91-7.
  • Goksu N, Haziroglu R, Kemaloglu Y, Karademir N, Bayramoglu I, Akyildiz N. Anatomy of the guinea pig temporal bone. Ann Otol Rhinol Laryngol 1992;101:699- 704.
  • Sichel JY, Plotnik M, Cherny L, Sohmer H, Elidan J. Surgical anatomy of the ear of the fat sand rat. J Otolaryngol 1999;28:217-22.
  • Judkins RF, Li H. Surgical anatomy of the rat middle ear. Otolaryngol Head Neck Surg 1997;117:438-47.
  • Browning GC, Granich MS. Surgical anatomy of the temporal bone in the chinchilla. Ann Otol Rhinol Laryngol 1978;87:875-82.
  • Preminger GM, Delvecchio FC, Birnbach JM. Digital image recording: an integral aspect of video endos- copy. Stud Health Technol Inform 1999;62:268-74.
  • Gürel Y, Bilgili A. Laboratuvar hayvanlarının aneste- zisi. Etlik Vet Mikrob Derg 2001;12:65-74.
  • Bojrab DI, Wiet RJ. Surgical anatomy of the temporal bone through dissection. In Glasscock ME, Shambaugh GE Jr, editors. Surgery of the ear. 4th ed. Philadelphia: W. B. Saunders Co; 1990. p. 579-618.
  • Kayhan FT, Algün Z. A histologic study on the tempo- ral bone of guinea pigs. Kulak Burun Bogaz Ihtis Derg 2003;10:51-7.
  • Sütbeyaz Y, Karaşen M. Guinea pig temporal kemik anatomisi. Kulak Burun Boğaz İhtisas Dergisi 1998; 5:173-7.
  • Adamczyk M, Appleton CM, Parell GJ, Antonelli PJ. Stapedectomy in the guinea pig. Otolaryngol Head Neck Surg 1999;121:581-4.
  • Wysocki J. Topographical anatomy of the guinea pig temporal bone. Hear Res 2005;199:103-10.
  • Amin S, Tucker AS. Joint formation in the middle ear: lessons from the mouse and guinea pig. Dev Dyn 2006;235:1326-33.
There are 14 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Arif Şanlı This is me

Sedat Aydın This is me

Resul Öztürk This is me

Publication Date March 12, 2009
Published in Issue Year 2009 Volume: 19 Issue: 2

Cite

APA Şanlı, A., Aydın, S., & Öztürk, R. (2009). Microscopic guide to the middle ear anatomy in guinea pigs. The Turkish Journal of Ear Nose and Throat, 19(2), 87-94.
AMA Şanlı A, Aydın S, Öztürk R. Microscopic guide to the middle ear anatomy in guinea pigs. Tr-ENT. March 2009;19(2):87-94.
Chicago Şanlı, Arif, Sedat Aydın, and Resul Öztürk. “Microscopic Guide to the Middle Ear Anatomy in Guinea Pigs”. The Turkish Journal of Ear Nose and Throat 19, no. 2 (March 2009): 87-94.
EndNote Şanlı A, Aydın S, Öztürk R (March 1, 2009) Microscopic guide to the middle ear anatomy in guinea pigs. The Turkish Journal of Ear Nose and Throat 19 2 87–94.
IEEE A. Şanlı, S. Aydın, and R. Öztürk, “Microscopic guide to the middle ear anatomy in guinea pigs”, Tr-ENT, vol. 19, no. 2, pp. 87–94, 2009.
ISNAD Şanlı, Arif et al. “Microscopic Guide to the Middle Ear Anatomy in Guinea Pigs”. The Turkish Journal of Ear Nose and Throat 19/2 (March 2009), 87-94.
JAMA Şanlı A, Aydın S, Öztürk R. Microscopic guide to the middle ear anatomy in guinea pigs. Tr-ENT. 2009;19:87–94.
MLA Şanlı, Arif et al. “Microscopic Guide to the Middle Ear Anatomy in Guinea Pigs”. The Turkish Journal of Ear Nose and Throat, vol. 19, no. 2, 2009, pp. 87-94.
Vancouver Şanlı A, Aydın S, Öztürk R. Microscopic guide to the middle ear anatomy in guinea pigs. Tr-ENT. 2009;19(2):87-94.