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Lipoma of the cerebellopontine angle: two cases report and review of literature

Year 2009, Volume: 19 Issue: 4, 207 - 211, 18.08.2009

Abstract

Here we report two cases with cerebellopontine angle lipoma. Cerebellopontine angle lipomas previously reported in the literature were reviewed. The review of the literature revealed the condition is more prevalent in women. The median tumor size was 10.26 range: 1 to 26 mm. It was noted that these tumors are most frequently associated with hearing loss 56% and tinnitus 40% , while 9% demonstrate no symptoms. Fifty-six percent of these patients had been operated, however complete resection had been accomplished in only 36% of patients. In our cases, the tumor sizes were 7x4 and 5x3 mm. Tinnitus and ear fullness were major complaints in both cases. One case had hearing loss and vertigo in addition to these complaints. Surgery was not performed for these cases. The patients have been followed up using same approach without any complication. Histopathological diagnosis is rarely necessary with the widespread use of magnetic resonance imaging. Because of the potential for significant morbidity with resection of these lesions, conservative follow-up is the best approach for cerebellopontine angle lipoma.

References

  • Flickinger JC, Lunsford LD, Coffey RJ, Linskey ME, Bissonette DJ, Maitz AH, et al. Radiosurgery of acous- tic neurinomas. Cancer 1991;67:345-53.
  • Harner SG, Laws ER Jr. Clinical findings in patients with acoustic neurinoma. Mayo Clin Proc 1983;58:721-8.
  • Donati F, Vassella F, Kaiser G, Blumberg A. Intracranial lipomas. Neuropediatrics 1992;23:32-8.
  • Truwit CL, Barkovich AJ. Pathogenesis of intracra- nial lipoma: an MR study in 42 patients. AJR Am J Roentgenol 1990;155:855-64.
  • Inoue T, Maeyama R, Ogawa H. Hemifacial spasm resulting from cerebellopontine angle lipoma: case report. Neurosurgery 1995;36:846-50.
  • Levin JM, Lee JE. Hemifacial spasm due to cerebel- lopontine angle lipoma: case report. Neurology 1987; 37:337-9.
  • Sprik C, Wirtschafter JD. Hemifacial spasm due to intracranial tumor. An international survey of bot- ulinum toxin investigators. Ophthalmology 1988; 95:1042-5.
  • Christensen WN, Long DM, Epstein JI. Cerebellopontine angle lipoma. Hum Pathol 1986;17:739-43.
  • Nakao S, Yamamoto T, Fukumitsu T, Ban S, Motozaki T, Sato S, et al. Cerebellopontine angle lipoma. Case report. Neurol Med Chir (Tokyo) 1988;28:1113-8. [Abstract]
  • Rosenbloom SB, Carson BS, Wang H, Rosenbaum AE, Udvarhelyi GB. Cerebellopontine angle lipoma. Surg Neurol 1985;23:134-8.
  • Behar PM, Dolan R, Dastur K, Marrangoni AG, Nayak N. Fibrovascular lipoma of the cerebellopontine angle mimicking trigeminal neuralgia. Ear Nose Throat J 1998;77:58-60.
  • Budka H. Intracranial lipomatous hamartomas (intrac- ranial “lipomas”). A study of 13 cases including com- binations with medulloblastoma, colloid and epider- moid cysts, angiomatosis and other malformations. Acta Neuropathol 1974;28:205-22.
  • Graves VB, Schemm GW. Clinical characteristics and CT findings in lipoma of the cerebellopontine angle. Case report. J Neurosurg 1982;57:839-41.
  • Kato T, Sawamura Y, Abe H. Trigeminal neural- gia caused by a cerebellopontine-angle lipoma: case report. Surg Neurol 1995;44:33-5.
  • Bilaniuk LT. Adult infratentorial tumors. Semin Roentgenol 1990;25:155-73.
  • Pensak ML, Glasscock ME 3rd, Gulya AJ, Hays JW, Smith HP, Dickens JR. Cerebellopontine angle lipo- mas. Arch Otolaryngol Head Neck Surg 1986;112: 99-101.
  • Tankéré F, Vitte E, Martin-Duverneuil N, Soudant J. Cerebellopontine angle lipomas: report of four cases and review of the literature. Neurosurgery 2002;50:626-31.
  • Saunders JE, Kwartler JA, Wolf HK, Brackmann DE, McElveen JT Jr. Lipomas of the internal auditory canal. Laryngoscope 1991;101:1031-7.
  • Heiss E, Guhl L, Mironov A. A lipoma of the cerebel- lopontile angle. Neurochirurgia (Stuttg) 1988;31:104-6. [Abstract]
  • Cohen TI, Powers SK, Williams DW 3rd. MR appear- ance of intracanalicular eighth nerve lipoma. AJNR Am J Neuroradiol 1992;13:1188-90.
  • Lenthall R, McConachie NS, Jefferson D. Cerebellopontine angle lipoma with an incidental scalp lipoma in a patient with hemifacial spasm. Eur Radiol 2000;10:195.
  • Faerber EN, Wolpert SM. The value of computed tomography in the diagnosis of intracranial lipomata. J Comput Assist Tomogr 1978;2:297-9.
  • Celik SE, Kocaeli H, Cordan T, Bekar A. Trigeminal neuralgia due to cerebellopontine angle lipoma. Case illustration. J Neurosurg 2000;92:889.
  • Bigelow DC, Eisen MD, Smith PG, Yousem DM, Levine RS, Jackler RK, et al. Lipomas of the internal audi- tory canal and cerebellopontine angle. Laryngoscope 1998;108:1459-69.
  • Salpietro FM, Alafaci C, Napoli P, Cipri S, Tomasello F. Cerebellopontine angle lipoma. Case report. J Neurosurg Sci 1994;38:55-8.
  • Zimmermann M, Kellermann S, Gerlach R, Seifert V. Cerebellopontine angle lipoma: case report and review of the literature. Acta Neurochir (Wien) 1999; 141:1347-51.
  • Bender MB. Cerebellopontine angle tumors or acoustic neuromas. Long-range management. Arch Otolaryngol 1973;97:160-5.
  • Mineta H, Nozue M, Ito H, Nozawa O, Nanba T. Acoustic tumor with hearing loss of sudden onset and recovery. Auris Nasus Larynx 1986;13(Suppl 2): S123-9.
  • Humphriss RL, Baguley DM, Axon PR, Moffat DA. Preoperative audiovestibular handicap in patients with vestibular schwannoma. Skull Base 2006;16:193-9.
  • Lalwani AK. Meningiomas, epidermoids, and other nonacoustic tumors of the cerebellopontine angle. Otolaryngol Clin North Am 1992;25:707-28.

Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi

Year 2009, Volume: 19 Issue: 4, 207 - 211, 18.08.2009

Abstract

Bu yazıda iki serebellopontin köşede lipomu olgusu sunuldu. Ayrıca literatürde yer alan serebellopon- tin köşede lipom olguları tartışıldı. Literatüre göre serebellopontin köşe lipomları kadınlarda daha sık görülmektedir. Bu olgularda tespit edilen tümörlerin boyutu ortalama 10.26 mm dağılım: 1-26 mm ola- rak bildirilmiştir. En sık başvuru semptomu %56 ile işitme kaybı iken bunu %40 ile çınlama takip etmek- teydi, hiç semptomu olmayan rastlantısal olguların oranı ise %9’du. Olguların %56’sına cerrahi girişim uygulanmış ancak bunların %36’sında tam rezeksi- yon yapılabilmiştir. Her iki olgumuzda da lezyonlar sağ kulaktaydı ve lezyonların ölçüsü 7x4 ve 5x3 mm idi. Kulakta çınlama ve dolgunluk hissi her iki olgu- daki başlıca yakınma nedenleriydi. Olgularımızdan birinde bu yakınmalara ek olarak işitme kaybı ve vertigo vardı. İki olguda da cerrahi girişim yapılmadı. Hastalar aynı yaklaşımla sorunsuz takip edilmek- tedir. Manyetik rezonans görüntülemenin kullanıma girmesiyle birlikte, histolojik olarak doğrulama gereği azalmıştır. Bu lezyonlara uygulanacak cerrahi sıra- sında morbidite oldukça yüksektir ve tam bir rezek- siyon olasılığı da düşük olduğundan tavsiye edilen yaklaşım yakın takiptir

References

  • Flickinger JC, Lunsford LD, Coffey RJ, Linskey ME, Bissonette DJ, Maitz AH, et al. Radiosurgery of acous- tic neurinomas. Cancer 1991;67:345-53.
  • Harner SG, Laws ER Jr. Clinical findings in patients with acoustic neurinoma. Mayo Clin Proc 1983;58:721-8.
  • Donati F, Vassella F, Kaiser G, Blumberg A. Intracranial lipomas. Neuropediatrics 1992;23:32-8.
  • Truwit CL, Barkovich AJ. Pathogenesis of intracra- nial lipoma: an MR study in 42 patients. AJR Am J Roentgenol 1990;155:855-64.
  • Inoue T, Maeyama R, Ogawa H. Hemifacial spasm resulting from cerebellopontine angle lipoma: case report. Neurosurgery 1995;36:846-50.
  • Levin JM, Lee JE. Hemifacial spasm due to cerebel- lopontine angle lipoma: case report. Neurology 1987; 37:337-9.
  • Sprik C, Wirtschafter JD. Hemifacial spasm due to intracranial tumor. An international survey of bot- ulinum toxin investigators. Ophthalmology 1988; 95:1042-5.
  • Christensen WN, Long DM, Epstein JI. Cerebellopontine angle lipoma. Hum Pathol 1986;17:739-43.
  • Nakao S, Yamamoto T, Fukumitsu T, Ban S, Motozaki T, Sato S, et al. Cerebellopontine angle lipoma. Case report. Neurol Med Chir (Tokyo) 1988;28:1113-8. [Abstract]
  • Rosenbloom SB, Carson BS, Wang H, Rosenbaum AE, Udvarhelyi GB. Cerebellopontine angle lipoma. Surg Neurol 1985;23:134-8.
  • Behar PM, Dolan R, Dastur K, Marrangoni AG, Nayak N. Fibrovascular lipoma of the cerebellopontine angle mimicking trigeminal neuralgia. Ear Nose Throat J 1998;77:58-60.
  • Budka H. Intracranial lipomatous hamartomas (intrac- ranial “lipomas”). A study of 13 cases including com- binations with medulloblastoma, colloid and epider- moid cysts, angiomatosis and other malformations. Acta Neuropathol 1974;28:205-22.
  • Graves VB, Schemm GW. Clinical characteristics and CT findings in lipoma of the cerebellopontine angle. Case report. J Neurosurg 1982;57:839-41.
  • Kato T, Sawamura Y, Abe H. Trigeminal neural- gia caused by a cerebellopontine-angle lipoma: case report. Surg Neurol 1995;44:33-5.
  • Bilaniuk LT. Adult infratentorial tumors. Semin Roentgenol 1990;25:155-73.
  • Pensak ML, Glasscock ME 3rd, Gulya AJ, Hays JW, Smith HP, Dickens JR. Cerebellopontine angle lipo- mas. Arch Otolaryngol Head Neck Surg 1986;112: 99-101.
  • Tankéré F, Vitte E, Martin-Duverneuil N, Soudant J. Cerebellopontine angle lipomas: report of four cases and review of the literature. Neurosurgery 2002;50:626-31.
  • Saunders JE, Kwartler JA, Wolf HK, Brackmann DE, McElveen JT Jr. Lipomas of the internal auditory canal. Laryngoscope 1991;101:1031-7.
  • Heiss E, Guhl L, Mironov A. A lipoma of the cerebel- lopontile angle. Neurochirurgia (Stuttg) 1988;31:104-6. [Abstract]
  • Cohen TI, Powers SK, Williams DW 3rd. MR appear- ance of intracanalicular eighth nerve lipoma. AJNR Am J Neuroradiol 1992;13:1188-90.
  • Lenthall R, McConachie NS, Jefferson D. Cerebellopontine angle lipoma with an incidental scalp lipoma in a patient with hemifacial spasm. Eur Radiol 2000;10:195.
  • Faerber EN, Wolpert SM. The value of computed tomography in the diagnosis of intracranial lipomata. J Comput Assist Tomogr 1978;2:297-9.
  • Celik SE, Kocaeli H, Cordan T, Bekar A. Trigeminal neuralgia due to cerebellopontine angle lipoma. Case illustration. J Neurosurg 2000;92:889.
  • Bigelow DC, Eisen MD, Smith PG, Yousem DM, Levine RS, Jackler RK, et al. Lipomas of the internal audi- tory canal and cerebellopontine angle. Laryngoscope 1998;108:1459-69.
  • Salpietro FM, Alafaci C, Napoli P, Cipri S, Tomasello F. Cerebellopontine angle lipoma. Case report. J Neurosurg Sci 1994;38:55-8.
  • Zimmermann M, Kellermann S, Gerlach R, Seifert V. Cerebellopontine angle lipoma: case report and review of the literature. Acta Neurochir (Wien) 1999; 141:1347-51.
  • Bender MB. Cerebellopontine angle tumors or acoustic neuromas. Long-range management. Arch Otolaryngol 1973;97:160-5.
  • Mineta H, Nozue M, Ito H, Nozawa O, Nanba T. Acoustic tumor with hearing loss of sudden onset and recovery. Auris Nasus Larynx 1986;13(Suppl 2): S123-9.
  • Humphriss RL, Baguley DM, Axon PR, Moffat DA. Preoperative audiovestibular handicap in patients with vestibular schwannoma. Skull Base 2006;16:193-9.
  • Lalwani AK. Meningiomas, epidermoids, and other nonacoustic tumors of the cerebellopontine angle. Otolaryngol Clin North Am 1992;25:707-28.
There are 30 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Nazım Korkut This is me

Hüseyin Işıldak This is me

Kemal Tuskan This is me

Şahin Öğreden This is me

Publication Date August 18, 2009
Published in Issue Year 2009 Volume: 19 Issue: 4

Cite

APA Korkut, N., Işıldak, H., Tuskan, K., Öğreden, Ş. (2009). Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi. The Turkish Journal of Ear Nose and Throat, 19(4), 207-211.
AMA Korkut N, Işıldak H, Tuskan K, Öğreden Ş. Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi. Tr-ENT. August 2009;19(4):207-211.
Chicago Korkut, Nazım, Hüseyin Işıldak, Kemal Tuskan, and Şahin Öğreden. “Serebellopontin köşe lipoması: İki Olgu Sunumu Ve literatürün değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat 19, no. 4 (August 2009): 207-11.
EndNote Korkut N, Işıldak H, Tuskan K, Öğreden Ş (August 1, 2009) Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi. The Turkish Journal of Ear Nose and Throat 19 4 207–211.
IEEE N. Korkut, H. Işıldak, K. Tuskan, and Ş. Öğreden, “Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi”, Tr-ENT, vol. 19, no. 4, pp. 207–211, 2009.
ISNAD Korkut, Nazım et al. “Serebellopontin köşe lipoması: İki Olgu Sunumu Ve literatürün değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat 19/4 (August 2009), 207-211.
JAMA Korkut N, Işıldak H, Tuskan K, Öğreden Ş. Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi. Tr-ENT. 2009;19:207–211.
MLA Korkut, Nazım et al. “Serebellopontin köşe lipoması: İki Olgu Sunumu Ve literatürün değerlendirilmesi”. The Turkish Journal of Ear Nose and Throat, vol. 19, no. 4, 2009, pp. 207-11.
Vancouver Korkut N, Işıldak H, Tuskan K, Öğreden Ş. Serebellopontin köşe lipoması: İki olgu sunumu ve literatürün değerlendirilmesi. Tr-ENT. 2009;19(4):207-11.