Abstract
Toxoplasmosis is caused by an obligate intracellular protozoan, Toxoplasma gondii, which can infect birds and mammals including humans. The disease is common throughout the world, and the most common clinical form is generalized or localized lymphadenopathy. However, in the literature, toxoplasmosis manifesting as a parotid mass is extremely rare. A 37-year-old female was admitted to our department with a painless mass in the parotid region, which had been present for one month. Upon physical examination, a hard, mobile, superficially located, and painless parotid mass with a size of 2x2 cm was detected. Following the diagnosis of a parotid neoplasm, a superficial parotidectomy was performed. Histopathological examination of the surgical specimen supported a diagnosis of toxoplasmosis lymphadenitis. Specific serum immunoglobulin levels were studied and results also confirmed the diagnosis of toxoplasmosis. The patient was given rovamycine for three weeks, and on 12 months follow-up, the patient was still free of recurrence.
References
- Montoya JG, Liesenfeld O. Toxoplasmosis. Lancet 2004; 363:1965-76.
- Moran WJ, Tom DW, King GD, Silverman ML. Toxoplasmosis lymphadenitis occurring in a parotid gland. Otolaryngol Head Neck Surg 1986;94:237-40.
- Akiner MN, Saatci MR, Yilmaz O, Erekul S. Intraglandular toxoplasmosis lymphadenitis of the parotid gland. J Laryngol Otol 1991;105:860-2.
- Shashy RG, Pinheiro D, Olsen KD. Toxoplasmosis lymphadenitis presenting as a parotid mass: a report of 2 cases. Ear Nose Throat J 2006;85:666-8.
- Hadi U, Rameh C. Intraglandular toxoplasmosis of the parotid gland pre- or postoperative diagnosis? Am J Otolaryngol 2007;28:201-4.
- Camacho AE, Goodman ML, Eavey RD. Pathologic correlation of the unknown solid parotid mass in chil- dren. Otolaryngol Head Neck Surg 1989;101:566-71.
- Langford RJ, Whear NM. Serology should be a routine investigation when presented with a major salivary gland lump. Br J Oral Maxillofac Surg 2000;38:158-9.
- Von Arx DP. Cervicofacial toxoplasmosis. Br J Oral Maxillofac Surg 1988;26:70-7.
- Pittam M, Thomas JM. Diseases of the pre-auricular lymph nodes mimicking parotid tumours. Br J Surg 1987;74:1172-3.
- McCabe RE, Brooks RG, Dorfman RF, Remington JS. Clinical spectrum in 107 cases of toxoplasmic lymph- adenopathy. Rev Infect Dis 1987;9:754-74.
Abstract
Toksoplazmosis, kuşlar ve insanlar dahil olmak üzere memelileri enfekte edebilen bir zorunlu hücre içi protozoon olan Toxoplazma gondii tara- fından oluşturulan bir enfeksiyondur. Hastalık dün- yanın her bölgesinde yaygındır ve en sık görülen klinik şekli yaygın veya bölgesel lenfadenopatidir. Ancak parotis kitlesi şeklinde ortaya çıkan tok- soplazmosis literatürde oldukça nadir bildirilmiştir. Otuz yedi yaşında bir kadın bir aydır olan parotis bölgesindeki ağrısız kitle nedeniyle kliniğimize başvurdu. Fizik muayenede 2x2 cm boyutlarında, sert, hareketli, yüzeyel yerleşimli ve ağrısız bir parotis kitlesi tespit edildi. Parotis neoplazmı tanısı ile yüzeyel parotidektomi uygulandı. Histopatolojik inceleme sonucu, toksoplazma lenfadeniti tanısını desteklemekteydi. Çalışılan spesifik serum immü- noglobulin değerleri de toksoplazmosis tanısını doğruladı. Hastaya üç hafta süreyle rovamycine tedavisi uygulandı ve 12 aylık takibinde hastalık nüksüne rastlanmadı
References
- Montoya JG, Liesenfeld O. Toxoplasmosis. Lancet 2004; 363:1965-76.
- Moran WJ, Tom DW, King GD, Silverman ML. Toxoplasmosis lymphadenitis occurring in a parotid gland. Otolaryngol Head Neck Surg 1986;94:237-40.
- Akiner MN, Saatci MR, Yilmaz O, Erekul S. Intraglandular toxoplasmosis lymphadenitis of the parotid gland. J Laryngol Otol 1991;105:860-2.
- Shashy RG, Pinheiro D, Olsen KD. Toxoplasmosis lymphadenitis presenting as a parotid mass: a report of 2 cases. Ear Nose Throat J 2006;85:666-8.
- Hadi U, Rameh C. Intraglandular toxoplasmosis of the parotid gland pre- or postoperative diagnosis? Am J Otolaryngol 2007;28:201-4.
- Camacho AE, Goodman ML, Eavey RD. Pathologic correlation of the unknown solid parotid mass in chil- dren. Otolaryngol Head Neck Surg 1989;101:566-71.
- Langford RJ, Whear NM. Serology should be a routine investigation when presented with a major salivary gland lump. Br J Oral Maxillofac Surg 2000;38:158-9.
- Von Arx DP. Cervicofacial toxoplasmosis. Br J Oral Maxillofac Surg 1988;26:70-7.
- Pittam M, Thomas JM. Diseases of the pre-auricular lymph nodes mimicking parotid tumours. Br J Surg 1987;74:1172-3.
- McCabe RE, Brooks RG, Dorfman RF, Remington JS. Clinical spectrum in 107 cases of toxoplasmic lymph- adenopathy. Rev Infect Dis 1987;9:754-74.
Details
| Primary Language | English |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 20, 2010 |
| Published in Issue | Year 2010 Volume: 20 Issue: 2 |