Oncocytic lipoadenoma of the parotid gland: a case report with fine needle aspiration cytology findings

Year 2010, Volume: 20 Issue: 3, 146 - 149, 30.06.2010

Çiğdem Tokyol Fatma H. Dilek Fatma Aktepe Abdullah Ayçiçek Ali Altuntaş

Abstract

Oncocytic lipoadenoma of the salivary gland is a rarely encountered tumor. A 56-year-old man presented with a two-year history of a slow-growing mass of the left parotid gland. Computed tomography scan with contrast showed a 7x6.5x6 cm well-circumscribed solid parotid mass of the left superficial and deep lobe. Fine-needle aspiration yielded oncocytic cells exclusively, suggesting Warthin tumor or an oncocytoma. Left total parotidectomy was performed. A diagnosis of oncocytic lipoadenoma was made. At six-month follow-up no evidence of recurrence has been noted. Oncocytic lipoadenoma should be considered in the differential diagnosis of oncocytic proliferations and oncocytic tumors in the parotid gland.

Keywords

Lipoadenoma, oncocyte, parotid gland

Parotis bezinde onkositik lipoadenom: İnce iğne aspirasyon sitolojisi bulguları ile birlikte bir olgu sunumu

Abstract

Tükürük bezinin onkositik lipoadenomu nadir görü- len bir tümördür. Elli altı yaşında erkek hasta sol parotis bezinde iki yıldır yavaş büyüyen kitle öykü- sü ile başvurdu. Kontrastlı bilgisayarlı tomografi incelemesinde sol süperfisyal ve alt derin lobda 7x6.5x6 cm boyutlarında solid iyi sınırlı parotis kitlesi saptandı. İnce iğne aspirasyon biyopsisinde görülen onkositik hücreler öncelikle Warthin tümörü veya onkositoma ön tanısını akla getirdi. Hastaya sol total parotidektomi uygulandı. Onkositik lipoa- denom tanısı konuldu. Altı aylık takipte yineleme izlenmedi. Parotisdeki onkositik proliferasyonların ve onkositik tümörlerin ayırıcı tanısında onkositik lipoadenom da düşünülmelidir

Keywords

Lipoadenom, onkosit, parotis bezi

References

• Batsakis JG. Tumors of the head and neck. Clinical and pathological considerations. 2nd ed. Baltimore: Williams & Wilkins; 1979.
• Tumors of the salivary glands. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. World Health Organization Classification of Tumors: Pathology and genetics of tumors of head and neck. Lyon: IARC Press; 2005. p. 209-81.
• Hirokawa M, Shimizu M, Manabe T, Ito J, Ogawa S. Oncocytic lipoadenoma of the submandibular gland. Hum Pathol 1998;29:410-2.
• Kato M, Horie Y. Oncocytic lipoadenoma of the parot- id gland. Histopathology 2000;36:285-6.
• Klieb HB, Perez-Ordoñez B. Oncocytic lipoadenoma of the parotid gland with sebaceous differentiation. Study of its keratin profile. Virchows Arch 2006; 449:722-5.
• Aouad R, Matar N, Sader-Ghorra C, Haddad A. Pathology quiz case 1. Oncocytic lipoadenoma of the parotid gland. Arch Otolaryngol Head Neck Surg 2008;134:446-8.
• Kandiloros D, Segas J, Papadimitriou K, Koutsomanis P, Adamopoulos G. Malignant oncocytoma of the parotid with oncocytic change of the contralateral gland. Am J Otolaryngol 1995;16:200-4.
• Ellis GL, Auclair PL. Benign epithelial neoplasms. In: Rosai J, Sobin LH, editors. Tumors of the salivary glands. Atlas of Tumor Pathology. 3rd ed. Washington: Armed Forces Institute of Pathology; 1996. p. 39-153.
• Takeda Y. Diffuse hyperplastic oncocytosis of the parot- id gland. Int J Oral Maxillofac Surg 1986;15:765-8.
• Brandwein MS, Huvos AG. Oncocytic tumors of major salivary glands. A study of 68 cases with follow-up of 44 patients. Am J Surg Pathol 1991;15:514-28.
• Chang A, Harawi SJ. Oncocytes, oncocytosis, and oncocytic tumors. Pathol Annu 1992;27:263-304.
• Palmer TJ, Gleeson MJ, Eveson JW, Cawson RA. Oncocytic adenomas and oncocytic hyperplasia of sal- ivary glands: a clinicopathological study of 26 cases. Histopathology 1990;16:487-93.
• Ramer N, Lumerman HS, Ramer Y. Sialolipoma: report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 104:809-13.