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Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives

Year 2013, Volume: 23 Issue: 3, 163 - 172, 19.08.2013

Abstract

Objectives: This study aims to evaluate the accuracy ratio of fine needle aspiration FNA cytology in the diagnosis of non-thyroidal head and neck masses. Patients and Methods: Between 2000 January and 2003 December, the pathology reports of 571 patients 297 males, 274 females; mean age 45 years; range 4 to 83 years with non-thyroidal head and neck masses who underwent FNA cytology during a four year period were retrospectively analyzed. Cytopathological and histopathological results of the samples were recorded. The smear results indicating an inconsistency were reviewed. The possible causes of the false positivity and false negativity were investigated. Results: Of a total of 571 patients, 181 had a confirmed histopathological diagnosis. The overall accuracy ratio, specificity, sensitivity, negative predictive value and positive predictive value of FNA in the diagnosis of the head and neck masses were 83%, 85%, 81%, 84%, 83%, respectively. Conclusion: The FNA has a high accuracy, sensitivity, specificity, negative and positive predictive values in the diagnosis of head and neck masses. If the major causes of misdiagnosis including inadequate sampling and misinterpretation are avoided, the diagnostic accuracy ratio of FNA in the head and neck and will be improved.

Baş ve boyun kitlelerinde ince iğne aspirasyon sitolojisi: Yanlış pozitif ve yanlış negatiflerin vurgulandığı sito-histopatolojik karşılaştırma çalışması

Year 2013, Volume: 23 Issue: 3, 163 - 172, 19.08.2013

Abstract

Amaç: Bu çalışmada, tiroid dışı baş ve boyun kitlelerinde ince iğne aspirasyon İİA sitolojisinin doğruluk oranı değerlendirildi.Hastalar ve Yöntemler: Dört yıllık süre boyunca Ocak 2000 - Aralık 2003 tiroid dışı baş ve boyun kitlelerine İİA sitolojisi yapılmış 571 hastanın 297 erkek, 274 kadın; ort. yaş 45 yıl; dağılım 4-83 yıl patoloji raporları retrospektif olarak incelendi. Alınan numunelerin sitopatolojik ve histopatolojik sonuçları kaydedildi. Uyumsuz smear sonuçları tekrar gözden geçirildi. Yanlış pozitiflik ve yanlış negatifliklerin muhtemel nedenleri araştırıldı.Bulgular: Toplam 571 hastanın 181’inin kesinleşmiş histopatolojik tanısı vardı. Baş ve boyun kitlelerinin tanısında İİA’nın genel doğruluk oranı, özgüllüğü, duyarlılığı, negatif beklenen değeri ve pozitif beklenen değeri sırasıyla %83, %85, %81, %84, %83 olarak bulundu.Sonuç: Baş ve boyun kitlelerinin tanısında İİA’nın doğruluğu, özgüllüğü, duyarlılığı, negatif ve pozitif beklenen değeri yüksektir. Yetersiz örnekleme ve yanlış yorumlama gibi başlıca yanlış tanı nedenleri önlenirse, İİA’nın baş ve boyun bölgesinde tanısal doğruluk oranı artacaktır

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Details

Primary Language English
Journal Section Research Article
Authors

İrem Onur Peker This is me

Sezer Kulaçoğlu This is me

Tuğrul Eruyar This is me

Gülüşan Ergül This is me

Publication Date August 19, 2013
Published in Issue Year 2013 Volume: 23 Issue: 3

Cite

APA Peker, İ. O., Kulaçoğlu, S., Eruyar, T., Ergül, G. (2013). Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives. The Turkish Journal of Ear Nose and Throat, 23(3), 163-172.
AMA Peker İO, Kulaçoğlu S, Eruyar T, Ergül G. Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives. Tr-ENT. August 2013;23(3):163-172.
Chicago Peker, İrem Onur, Sezer Kulaçoğlu, Tuğrul Eruyar, and Gülüşan Ergül. “Fine Needle Aspiration Cytology of Head and Neck Masses: A Cytohistopathological Correlation Study With Emphasis on False Positives and False Negatives”. The Turkish Journal of Ear Nose and Throat 23, no. 3 (August 2013): 163-72.
EndNote Peker İO, Kulaçoğlu S, Eruyar T, Ergül G (August 1, 2013) Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives. The Turkish Journal of Ear Nose and Throat 23 3 163–172.
IEEE İ. O. Peker, S. Kulaçoğlu, T. Eruyar, and G. Ergül, “Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives”, Tr-ENT, vol. 23, no. 3, pp. 163–172, 2013.
ISNAD Peker, İrem Onur et al. “Fine Needle Aspiration Cytology of Head and Neck Masses: A Cytohistopathological Correlation Study With Emphasis on False Positives and False Negatives”. The Turkish Journal of Ear Nose and Throat 23/3 (August 2013), 163-172.
JAMA Peker İO, Kulaçoğlu S, Eruyar T, Ergül G. Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives. Tr-ENT. 2013;23:163–172.
MLA Peker, İrem Onur et al. “Fine Needle Aspiration Cytology of Head and Neck Masses: A Cytohistopathological Correlation Study With Emphasis on False Positives and False Negatives”. The Turkish Journal of Ear Nose and Throat, vol. 23, no. 3, 2013, pp. 163-72.
Vancouver Peker İO, Kulaçoğlu S, Eruyar T, Ergül G. Fine needle aspiration cytology of head and neck masses: a cytohistopathological correlation study with emphasis on false positives and false negatives. Tr-ENT. 2013;23(3):163-72.