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Effects of topical sprays on allergy-induced nasal obstruction in children

Year 2013, Volume: 23 Issue: 4, 217 - 224, 28.09.2013

Abstract

Objectives: This study aims to evaluate the efficacy of mometasone furoate nasal spray, intranasal azelastine, and isotonic sea water nasal spray in the management of allergy-induced nasal obstruction. Patients and Methods: Between October 2007 and August 2008 60 patients 37 males, 23 females; mean age 9.8±2.6 years; range 7 to 16 years with a history of allergic rhinitis were included in the study. Laboratory assays including the skin prick test, nasal smear, phadiatop, total immunoglobulin E IgE , and complete blood count test were performed. The patients were classified into three groups including 20 in each, according to the topical treatment administered. Patients in group 1 received azelastine, group 2 received mometasone furoate nasal spray, and group 3 received isotonic sea water nasal spray. Nasal passage volume was calculated using an acoustic rhinometry device. Results: Azelastine and mometasone furoate decreased nasal congestion and increased nasal cavity volume more effectively, compared to isotonic sea water nasal spray. Conclusion: Mometasone furoate and azelastine which decrease nasal congestion and increase nasal volume are effective in the management of allergic rhinitis in children.

Çocuklarda topical spreylerin allerjiye bağlı burun tıkanıklığı üzerindeki etkileri

Year 2013, Volume: 23 Issue: 4, 217 - 224, 28.09.2013

Abstract

Amaç: Bu çalışmada allerjiye bağlı burun tıkanıklığının tedavisinde mometazon furoat burun spreyi, burun içi azelastin ve izotonik deniz suyu burun spreyinin etkinliği değerlendirildi.Hastalar ve Yöntemler: Ekim 2007 - Ağustos 2008 tarihleri arasında alerjik rinit öyküsü olan 60 hasta 37 erkek, 23 kadın; ort. yaş 9.8±2.6 yıl; dağılım 7-16 yıl çalışmaya dahil edildi. Laboratuvar yöntemleri olarak deri prik testi, burun sürüntü testi, fadiotop, total immünoglobulin E IgE ve tam kan sayımı yapıldı. Hastalar uygulanan topikal tedaviye göre 20’şerli üç gruba ayrıldı. Grup 1’deki hastalara azelastin, grup 2’dekilere mometazon furoat burun spreyi, grup 3’dekilere izotonik deniz suyu burun spreyi uygulandı. Burun pasaj hacmi, akustik rinometri aleti kullanılarak hesaplandı.Bulgular: Mometazon furoat ve azelastin, izotonik deniz suyu burun spreyine kıyasla, daha etkin şekilde nazal konjesyonu azalttı ve burun hacmini artırdı.Sonuç: Burun konjesyonunu azaltan ve burun hacmini artıran mometazon furoat ve azelastin, çocuklarda alerjik rinitin tedavisinde etkilidir

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Details

Primary Language English
Journal Section Research Article
Authors

Mehmet Yaşar This is me

İsmail Önder Uysal This is me

Emine Elif Altuntaş This is me

Ömer Cevit This is me

Suphi Müderris This is me

Publication Date September 28, 2013
Published in Issue Year 2013 Volume: 23 Issue: 4

Cite

APA Yaşar, M., Uysal, İ. Ö., Altuntaş, E. E., Cevit, Ö., et al. (2013). Effects of topical sprays on allergy-induced nasal obstruction in children. The Turkish Journal of Ear Nose and Throat, 23(4), 217-224.
AMA Yaşar M, Uysal İÖ, Altuntaş EE, Cevit Ö, Müderris S. Effects of topical sprays on allergy-induced nasal obstruction in children. Tr-ENT. September 2013;23(4):217-224.
Chicago Yaşar, Mehmet, İsmail Önder Uysal, Emine Elif Altuntaş, Ömer Cevit, and Suphi Müderris. “Effects of Topical Sprays on Allergy-Induced Nasal Obstruction in Children”. The Turkish Journal of Ear Nose and Throat 23, no. 4 (September 2013): 217-24.
EndNote Yaşar M, Uysal İÖ, Altuntaş EE, Cevit Ö, Müderris S (September 1, 2013) Effects of topical sprays on allergy-induced nasal obstruction in children. The Turkish Journal of Ear Nose and Throat 23 4 217–224.
IEEE M. Yaşar, İ. Ö. Uysal, E. E. Altuntaş, Ö. Cevit, and S. Müderris, “Effects of topical sprays on allergy-induced nasal obstruction in children”, Tr-ENT, vol. 23, no. 4, pp. 217–224, 2013.
ISNAD Yaşar, Mehmet et al. “Effects of Topical Sprays on Allergy-Induced Nasal Obstruction in Children”. The Turkish Journal of Ear Nose and Throat 23/4 (September 2013), 217-224.
JAMA Yaşar M, Uysal İÖ, Altuntaş EE, Cevit Ö, Müderris S. Effects of topical sprays on allergy-induced nasal obstruction in children. Tr-ENT. 2013;23:217–224.
MLA Yaşar, Mehmet et al. “Effects of Topical Sprays on Allergy-Induced Nasal Obstruction in Children”. The Turkish Journal of Ear Nose and Throat, vol. 23, no. 4, 2013, pp. 217-24.
Vancouver Yaşar M, Uysal İÖ, Altuntaş EE, Cevit Ö, Müderris S. Effects of topical sprays on allergy-induced nasal obstruction in children. Tr-ENT. 2013;23(4):217-24.