Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia

Year 2014, Volume: 24 Issue: 5, 254 - 258, 15.10.2014

İsa Özbay Metehan Gençoğlu Hasan Hüseyin Balıkçı Cüneyt Kucur Fatih Oğhan

Abstract

Objectives: This study aims to evaluate the necessity of routine histopathological analyses of tonsillectomy specimens. Patients and Methods: A retrospective review for 2,004 patients 1,048 males, 956 females; mean age 12.2 years; range 2 to 60 years who underwent tonsillectomy between January 2009 and May 2013 was carried out at the Diyarbakır Training and Research Hospital, Turkey. Tonsillectomy specimens were fixed with formalin, and stained with hematoxylin and eosin before being sectioned and examined via light microscope. Chronic inflammation and lymphoid hyperplasia were considered non-significant pathological findings. Other pathological diagnoses including infectious processes, and benign and malignant neoplasms were regarded as significant pathological findings. Results: Non-significant pathological findings -chronic inflammation, lymphoid hyperplasia or both- were observed in 1,972 patients. Significant pathological findings -epidermal cyst, mucocele, squamous papilloma, granuloma and squamous cell carcinoma- were observed in 32 patients. One patient was diagnosed with squamous cell carcinoma, and another had granulomatous disease diagnosed as tuberculosis. Conclusion: Histopathological examination is only necessary for patients with preoperative risk factors. Gross examination may be a good alternative since it is cost effective and not time consuming.

Keywords

Histopathology, malignancy, routine, tonsillectomy

Tonsillektomi numunelerinin histopatolojik analizi: Güneydoğu Anadolu’dan bir rapor

Abstract

Amaç: Bu çalışmada tonsillektomi numunelerinin rutin histopatolojik analizlerinin gerekliliği değerlendirildi.Hastalar ve Yöntemler: Diyarbakır Eğitim ve Araştırma Hastanesi’nde Ocak 2009 ve Mayıs 2013 tarihleri arasında tonsillektomi geçiren 2.004 hasta 1.048 erkek, 956 kadın; ort. yaş 12.2 yıl; dağılım 2-60 yıl için retrospektif bir inceleme yapıldı. Tonsillektomi numuneleri kesitlere ayrılıp ışık mikroskobu ile incelenmeden önce formalin ile tespit edildi ve hematoksilen ve eozin ile boyandı. Kronik enflamasyon ve lenfoid hiperplazi anlamlı olmayan patolojik bulgular olarak kabul edildi. Enfeksiyöz süreçler, iyi huylu ve kötü huylu neoplazmlar gibi diğer patolojik tanılar anlamlı patolojik bulgular olarak dikkate alındı.Bulgular: Kronik enflamasyonu, lenfoid hiperplaziyi veya her ikisini içeren anlamlı olmayan patolojik bulgular 1.972 hastada gözlemlendi. Epidermal kist, mukosel, skuamöz papillom, granülom ve skuamöz hücreli karsinomu içeren anlamlı patolojik bulgular 32 hastada gözlemlendi. Bir hastaya skuamöz hücreli karsinom tanısı konuldu, bir diğerinde tüberküloz tanısı konulan granülomatöz hastalık vardı.Sonuç: Histopatolojik inceleme sadece ameliyat öncesi risk faktörleri olan hastalar için gereklidir. Maliyet etkin olup zaman alıcı olmayan makroskopik inceleme iyi bir seçenek olabilir

Keywords

Histopatoloji, malignite, rutin, tonsillektomi

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