Prevalence of allergic fungal rhinosinusitis among patients with chronic rhinosinusitis with or without nasal polyposis who underwent endonasal sinus surgery in Northwestern Turkey

Year 2014, Volume: 24 Issue: 5, 259 - 264, 15.10.2014

Deniz Demir Yusufhan Süoğlu Mehmet Güven Mahmut Sinan Yılmaz

Abstract

Objectives: This study aims to evaluate the prevalence of allergic fungal rhinosinusitis in chronic rhinosinusitis patients in the northwest of Turkey. Patients and Methods: Eighty-seven patients diagnosed with chronic rhinosinusitis and who were planned endonasal sinus surgery were enrolled in this prospective study. Patients were evaluated by detailed clinical examination, computed tomography, skin test against allergens, total serum immunoglobulin E IgE antibody, fungal-specific IgE antibody, and histopathologic and mycologic monitoring. Results: Fungal elements showing tissue invasiveness were detected in only four patients. These patients had specific IgE against Aspergillus fumigatus 4.6% . Skin tests were positive for at least one allergen in 16 patients 18.3% . Conclusion: None of the patients met diagnostic criteria for allergic fungal rhinosinusitis. This result may be due to the diversity in disease prevalence based on geographical location or diagnostic methods.

Keywords

Allergy, fungus, nasal polyp, prevalence, sinusitis

Türkiye’nin Kuzeybatısında endoskopik sinüs cerrahisi uygulanan nazal polipli ya da polipsiz kronik rinosinüzit hastalarında alerjik fungal sinüzit yaygınlığı

Abstract

Amaç: Bu çalışmada Türkiye’nin kuzeybatısındaki kronik rinosinüzit hastalarında alerjik fungal rinosinüzit yaygınlığı araştırıldı.Hastalar ve Yöntemler: Bu prospektif çalışmaya kronik rinosinüzit tanısı konulup endonazal sinüs cerrahisi planlanan 87 hasta dahil edildi. Hastalar ayrıntılı klinik muayene, bilgisayarlı tomografi, alerjenlere ve total serum immünoglobulin E IgE ve mantar spesifik IgE antikora karşı deri testi ve histopatolojik ve mikolojik izlem ile değerlendirildi.Bulgular: Doku invazyonu gösteren fungal elementler yalnız dört hastada tespit edildi. Bu hastalarda Aspergillus fumigatusa karşı spesifik IgE vardı %4.6 . On altı hastada deri testleri en az bir alerjen için pozitifti %18.3 . Sonuç: Hastaların hiçbiri alerjik fungal rinosinüzit tanı kriterlerini karşılamadı. Bu sonuç, hastalığın yaygınlığının coğrafi konuma göre farklılaşmasından ya da tanı yöntemlerinden kaynaklanabilir

Keywords

Alerji, mantar, nazal polip, yaygınlık, sinüzit

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