Efficacy of multimodality approach to sudden hearing loss

Year 2015, Volume: 25 Issue: 2, 77 - 81, 20.05.2015

Barış Naiboğlu Semra Külekçi Mehmet Sürmeli Ayşegül Verim Çiğdem Kalaycık Ertuğay Önder İhvan Lütfü Şeneldir Sema Zer Toros

Abstract

Objectives: This study aims to investigate whether addition of intratympanic steroid ITS to systemic steroid and hyperbaric oxygen HBO is effective in the treatment of sudden hearing loss SHL . Patients and Methods: Between January 2008 and October 2011, 58 patients diagnosed with SHL were enrolled in the study. Twenty patients 11 males, 9 females; mean age 45.3±21 years; range 24 to 66 years who received systemic steroid and HBO composed group 1, while 38 patients 19 males, 19 females; mean age 41.6±16 years; range 25 to 61 years who received ITS in addition to systemic steroid and HBO composed group 2. Results: Post-treatment hearing improvement was statistically significant in both groups in terms of the mean pure tone according to the Siegel’s criteria p<0.05 . Treatment was successful at 55% of patients in group 1 and 63% in group 2. Despite increased success rate with the addition of ITS, it did not indicate statistical significance p>0.05 . However, there was a strong statistically significant difference in terms of profound hearing loss over 90 dB p<0.05 . None of six patients 0% with profound hearing loss in group 1 benefited treatment, while addition of ITS to the treatment yielded success in six of 12 patients with profound hearing loss 50% in group 2 p<0.05 . Conclusion: Addition of ITS to systemic steroid and HBO treatment may yield better results in patients with SHL. However, ITS injection seems beneficial for patients with profound SHL.

Keywords

Hyperbaric oxygen, intratympanic steroid, sudden sensorineural hearing loss

Ani işitme kaybında çoklu tedavi yaklaşımın etkinliği

Abstract

Amaç: Bu çalışmada ani işitme kaybının AİK tedavisinde sistemik steroid ve hiperbarik oksijene HBO ilave olarak intratimpanik steroidin ITS etkinliği araştırıldı.Hastalar ve Yöntemler: Ocak 2008 - Ekim 2011 tarihleri arasında AİK tanısı konulan 58 hasta çalışmaya dahil edildi. Sistemik steroid ve HBO tedavisi uygulanan 20 hasta 11 erkek, 9 kadın; ort. yaş 45.3±21 yıl; dağılım 24-66 yıl grup 1’i oluştururken; sistemik steroid ve HBO tedavisine ek olarak ITS tedavisi uygulanan 38 hasta 19 erkek, 19 kadın; ort. yaş 41.6±16 yıl; dağılım 25-61 yıl grup 2’yi oluşturdu.Bulgular: Tedavi sonrası iyileşme oranları, Siegel kriterlerine göre saf ses ortalamalarında her iki grup arasında istatistiksel olarak anlamlı bulundu p0.05 . Ancak 90 dB üzeri derin işitme kayıplarında güçlü bir istasitiksel fark vardı p

Keywords

Hiperbarik oksijen, intratimpanik steroid, ani sensörinöral işitme kaybı

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