Sinonasal inflammatory myofibroblastic pseudotumor plasma cell granuloma

Year 2015, Volume: 25 Issue: 3, 174 - 178, 19.07.2015

Rabia Bozdoğan Arpacı Tuba Kara Esen Özyedek Ebru Serinsöz Yusuf Vayısoğlu Anıl Özgür Taner Arpacı Cengiz Özcan

Abstract

Inflammatory myofibroblastic pseudotumor plasma cell granuloma is a soft tissue lesion consisting of myofibroblasts, mature lymphocytes, histiocytes, plasma cells, eosinophils, and extracellular collagen. Various sites in the body may harbor these lesions. Lungs, omentum, intestines, mesentery, and urinary system are the most susceptible areas. It is usually seen in children and young adults. The lesion is rarely detected in the head and neck region. The orbit and the upper respiratory system are the most common localizations in the head and neck region. Sinonasal tract is a rare site of involvement. The differential diagnosis includes squamous cell carcinoma spindle cell variant , inflammatory fibrosarcoma, leiomyosarcoma, schwannoma, and nonspecific inflammation. Our patient who had a sinonasal mass showed a benign tumor consisting of spindle tumor cells and inflammatory cells histopathologically. This case was presented due to its rare existence to this site.

Keywords

Inflammatory myofibroblastic pseudotumor, plasma cell granuloma, sinonasal

Sinonazal enflamatuvar miyofibroblastik psödotümör plazma hücreli granülom

Abstract

Enflamatuvar miyofibroblastik psödotümör plazma hücreli granülom miyofibroblastlar, olgun lenfositler, histiositler, plazma hücreleri, eozinofiller ve ekstraselüler kollajenden oluşan bir yumuşak doku lezyonudur. Bu lezyonlar vücuttaki çeşitli bölgelerde bulunabilir. Akciğerler, omentum, bağırsaklar, mezenter ve üriner sistem riske en açık alanlardır. Genellikle çocuklar ve genç erişkinlerde görülür. Lezyon baş ve boyun bölgesinde nadiren tespit edilir. Baş ve boyun bölgesinde orbit ve üst solunum sistemi en yaygın yerleşim yerleridir. Sinonazal yol nadir bir tutulum bölgesidir. Ayırıcı tanı skuamöz hücreli karsinom iğsi hücreli varyant , enflamatuvar fibrosarkom, leiomiyosarkom, schwannom ve nonspesifik enflamasyonu içerir. Sinonazal kitlesi olan hastamızda histopatolojik olarak iğsi tümör hücreleri ve enflamatuvar hücrelerden oluşan iyi huylu bir tümör görüldü. Bu olgu bu alandaki nadir oluşumu nedeniyle sunuldu

Keywords

Enflamatuvar miyofibroblastik psödotümör, plazma hücreli granülom, sinonazal

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