The relationship between platelet count and mean platelet volume with obstructive sleep apnea syndrome

Year 2015, Volume: 25 Issue: 5, 289 - 294, 10.10.2015

Doğan Atan Fatma Cemre Sazak Kundi Kürşat Murat Özcan Hüseyin Dere

Abstract

Objectives: This study aims to investigate the relationship between platelet count and mean platelet volume MPV with obstructive sleep apnea syndrome OSAS . Patients and Methods: This retrospective study included 417 OSAS patients 284 males, 133 females; mean age 47.9±10.0; range 23 to 75 years who were performed polisomnography PSG in our clinic between January 2013 and December 2014. Patients were divided into two groups according to apnea-hipopnea index AHI . Apnea-hipopnea index <5 was assumed as normal, while AHI ≥5 was assumed as OSAS. Platelet count and MPV values of group with normal AHI and group with OSAS were statistically compared. Apneahipopnea index, REM AHI, non-REM AHI, minimum oxygen saturation, and duration of oxygen saturation remaining below 90% were statistically compared with platelet count and MPV. Results: The mean of platelet count in non-OSAS and OSAS groups were 262.31±65.78 and 252.77±61.86, respectively, with no statistically significant difference between the groups. Mean platelet volume in non-OSAS and OSAS groups were 9.56±1.88 and 9.71±1.57, respectively; however, the difference was not statistically significant. Platelet count increased statistically significantly as AHI, REM AHI, non-REM AHI, and minimum oxygen saturation parameters got impaired. Conclusion: As PSG parameters get impaired, platelet count increases in OSAS patients.

Keywords

Mean platelet volume, platelet, polysomnography, sleep apnea

Trombosit sayısı ve ortalama trombosit hacminin tıkayıcı uyku apne sendromu ile ilişkisi

Abstract

Amaç: Bu çalışmada trombosit sayısı ve ortalama trombosit hacmi OTH ile tıkayıcı uyku apne sendromu TUAS arasındaki ilişki araştırıldı.Hastalar ve Yöntemler: Bu retrospektif çalışmaya Ocak 2013 - Aralık 2014 tarihleri arasında kliniğimizde polisomnografi PSG yapılan 417 TUAS hastası 284 erkek, 133 kadın; ort. yaş 47.9±10.0; dağılım 23-75 yıl dahil edildi. Hastalar apne hipopne indeksine AHİ göre iki gruba ayrıldı. Apne hipopne indeksi

Keywords

Ortalama trombosit hacmi, trombosit, polisomnografi, uyku apnesi

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