Hyoid osteoradionecrosis accompanied by candida infection

Year 2015, Volume: 25 Issue: 5, 310 - 314, 10.10.2015

Güler Yavaş Gonca Kara Gedik Bahar Çolpan Özlem Ata Kayhan Öztürk Oktay Sarı

Abstract

Osteoradionecrosis of the hyoid bone is a rare complication of therapeutic irradiation performed for head and neck cancer. In this article, we present a 52-year-old male patient who admitted with severe odynophagia following chemo-radiotherapy administration for tonsil carcinoma. Fluorine-18-fluorodeoxy-glucose positron emission tomography-computed tomography revealed a metabolic activity in hyoid bone. The pathological findings were consistent with fungal infection and hyoid bone necrosis. Hyoid osteoradionecrosis should be kept in mind in patients with intractable dysphagia following irradiation for head and neck tumors.

Keywords

Head and neck cancer, hyoid, osteoradionecrosis, radiotherapy, squamous cell carcinoma

Kandida enfeksiyonuna eşlik eden hyoid osteoradyonekrozu

Abstract

Hyoid kemiğin osteoradyonekrozu baş ve boyun kanseri için uygulanan terapötik irradyasyonun nadir bir komplikasyonudur. Bu yazıda, tonsil karsinomu nedeni ile kemoradyoterapi uygulamasının ardından ciddi odinofaji ile başvuran 52 yaşında bir erkek hasta sunuldu. Florin-18-florodeoksi-glukoz pozitron emisyon tomografi-bilgisayarlı tomografide hyoid kemikte metabolik aktivite görüldü. Patolojik bulgular fungal enfeksiyon ve hyoid kemik nekrozu ile uyumlu idi. Baş ve boyun tümörlerine yönelik irradyasyon ardından inatçı disfajisi olan hastalarda hyoid osteoradyonekrozu akılda tutulmalıdır

Keywords

Baş ve boyun kanseri, hyoid, osteoradyonekroz, radyoterapi, yassı hücreli karsinom

References

• Rathy R, Sunil S, Nivia M. Osteoradionecrosis of mandible: Case report with review of literature. Contemp Clin Dent 2013;4:251-3.
• Bhatia PL, Dutta NK, Sanasam JC. Osteonecrosis of hyoid bone and thyroid cartilage. Arch Otolaryngol 1979;105:553-4.
• Robertson JS, Frauenhoffer EE, Stryker J, Schaitkin B, Velkley DE, McGinn JD. Osteoradionecrosis of the hyoid induced by combined modality therapy for laryngeal carcinoma. Ear Nose Throat J 1995;74:578-81.
• Monceaux G, Périé S, Montravers F, Angelard B, Corlieu P, St Guily JL. Osteoradionecrosis of the hyoid bone: a report of 3 cases. Am J Otolaryngol 1999;20:400-4.
• Smith WK, Pfleiderer AG, Millet B. Osteoradionecrosis of the hyoid presenting as a cause of intractable neck pain following radiotherapy and the role of magnetic resonance image scanning to aid diagnosis. J Laryngol Otol 2003;117:1003-5.
• Danic D, Penavic IP, Rubin O, Pandak N, Matic I, Hadzibegovic AD. Actinomycosis and osteochondroradionecrosis of the hyoid bone and thyroid cartilage. J Otolaryngol Head Neck Surg 2008;37:62-4.
• Yoo JS, Rosenthal DI, Mitchell K, Ginsberg LE. Osteoradionecrosis of the hyoid bone: imaging findings. AJNR Am J Neuroradiol 2010;31:761-6.
• Chard R, Monroe MM, Andersen PE. Hyoid osteoradionecrosis associated with carotid rupture: report of 2 cases. Head Neck 2013;35:36-8.
• Madrid C, Abarca M, Bouferrache K. Osteoradionecrosis: an update. Oral Oncol 2010;46:471-4.
• Nabil S, Samman N. Risk factors for osteoradionecrosis after head and neck radiation: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol 2012;113:54-69.
• Cooper JS, Pajak TF, Forastiere AA, Jacobs J, Campbell BH, Saxman SB, et al. Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med 2004;350:1937-44.