BibTex RIS Cite

Role of nasal problems on positional and nonpositional obstructive sleep apnea

Year 2016, Volume: 26 Issue: 4, 219 - 224, 10.09.2016

Abstract

Objectives: This study aims to examine the relationship between nasal pathologies and positional PP obstructive sleep apnea OSA or nonpositional NPP OSA. Patients and Methods: A total of 44 male OSA patients mean age 48.0±6.8 years; range 31 to 60 years suffering from nasal obstruction were retrospectively evaluated for nasal obstruction scores, overall apnea hypopnea index AHI and AHI in supine and nonsupine positions, daytime sleepiness scores, and body mass index BMI . Patients were divided into two equal groups as PP group and NPP group. Output parameters were snoring severity index, clinical nasal obstruction score, septal deviation score, conchal hypertrophy score, and allergic rhinitis AR score. These parameters were correlated with the type of OSA. Results: Apnea hypopnea index was significantly lower in PP group than in NPP group p<0.03 . Spearman correlation analysis revealed significant negative correlation between AR score and PP r=-0.40, p<0.0001 . Pearson correlation test revealed significant correlation between AHI and BMI r=0.32, p<0.05 . Conclusion: We suggest that AR is not only an important risk factor for OSA, but also patients with AR tend to be NPP OSA patients because of the serious nasal obstruction which already causes an increase in nasal resistance or pharyngeal collapsibility.

References

  • Oksenberg A, Khamaysi I, Silverberg DS, Tarasiuk A. Association of body position with severity of apneic events in patients with severe nonpositional obstructive sleep apnea. Chest 2000;118:1018-24.
  • Ozeke O, Erturk O, Gungor M, Hızel SB, Aydın D, Celenk MK, et al. Influence of the right- versus left-sided sleeping position on the apnea-hypopnea index in patients with sleep apnea. Sleep Breath 2012;16:617-20.
  • Chung JW, Enciso R, Levendowski DJ, Westbrook PR, Clark GT. Patients with positional versus nonpositional obstructive sleep apnea: a retrospective study of risk factors associated with apnea-hypopnea severity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:605-10.
  • Oksenberg A, Silverberg DS. The effect of body posture on sleep-related breathing disorders: facts and therapeutic implications. Sleep Med Rev 1998;2:139-62.
  • Rundcrantz H. Postural variations of nasal patency. Acta Otolaryngol 1969;68:435-43.
  • De Vito A, Berrettini S, Carabelli A, Sellari-Franceschini S, Bonanni E, Gori S, et al. The importance of nasal resistance in obstructive sleep apnea syndrome: a study with positional rhinomanometry. Sleep Breath 2001;5:3-11.
  • Patel AV, Hwang D, Masdeu MJ, Chen GM, Rapoport DM, Ayappa I. Predictors of response to a nasal expiratory resistor device and its potential mechanisms of action for treatment of obstructive sleep apnea. J Clin Sleep Med 2011;7:13-22.
  • Penzel T, Möller M, Becker HF, Knaack L, Peter JH. Effect of sleep position and sleep stage on the collapsibility of the upper airways in patients with sleep apnea. Sleep 2001;24:90-5.
  • Ong JS, Touyz G, Tanner S, Hillman DR, Eastwood PR, Walsh JH. Variability of human upper airway collapsibility during sleep and the influence of body posture and sleep stage. J Sleep Res 2011;20:533-7.
  • Pracharktam N, Hans MG, Strohl KP, Redline S. Upright and supine cephalometric evaluation of obstructive sleep apnea syndrome and snoring subjects. Angle Orthod 1994;64:63-73.
  • Ono T, Lowe AA, Ferguson KA, Fleetham JA. Associations among upper airway structure, body position, and obesity in skeletal Class I male patients with obstructive sleep apnea. Am J Orthod Dentofacial Orthop 1996;109:625-34.
  • Virkkula P, Maasilta P, Hytönen M, Salmi T, Malmberg H. Nasal obstruction and sleep-disordered breathing: the effect of supine body position on nasal measurements in snorers. Acta Otolaryngol 2003;123:648-54.
  • Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath 2008;12:161-8.
  • Rhee CS, Kim DY, Won TB, Lee HJ, Park SW, Kwon TY, et al. Changes of nasal function after temperature- controlled radiofrequency tissue volume reduction for the turbinate. Laryngoscope 2001;111:153-8.
  • Sapçi T, Sahin B, Karavus A, Akbulut UG. Comparison of the effects of radiofrequency tissue ablation, CO2 laser ablation, and partial turbinectomy applications on nasal mucociliary functions. Laryngoscope 2003;113:514-9.
  • Yilmaz M, Kemaloğlu YK, Baysal E, Tutar H. Radiofrequency for inferior turbinate hypertrophy: could its long-term effect be predicted with a preoperative topical vasoconstrictor drop test? Am J Rhinol 2006;20:32-5.
  • Schwartz AR, Patil SP, Laffan AM, Polotsky V, Schneider H, Smith PL. Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches. Proc Am Thorac Soc 2008;5:185-92.
  • Ugur KS, Ark N, Kurtaran H, Kizilbulut G, Cakir B, Ozol D, et al. Subcutaneous fat tissue thickness of the anterior neck and umbilicus in patients with obstructive sleep apnea. Otolaryngol Head Neck Surg 2011;145:505-10.
  • McNicholas WT, Tarlo S, Cole P, Zamel N, Rutherford R, Griffin D, et al. Obstructive apneas during sleep in patients with seasonal allergic rhinitis. Am Rev Respir Dis 1982;126:625-8.
  • Young T, Finn L, Palta M. Chronic nasal congestion at night is a risk factor for snoring in a population-based cohort study. Arch Intern Med 2001;161:1514-9.
  • Ferguson BJ. Influences of allergic rhinitis on sleep. Otolaryngol Head Neck Surg 2004;130:617-29.
  • Kalpaklioğlu AF, Kavut AB, Ekici M. Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. Ann Allergy Asthma Immunol 2009;103:20-5.
  • Meng J, Xuan J, Qiao X, Li X, Liu S, Lukat KF, et al. Assessment of sleep impairment in persistent allergic rhinitis patients using polysomnography. Int Arch Allergy Immunol 2011;155:57-62.
  • Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008;63:8-160.

Burun problemlerinin pozisyonel ve pozisyonel olmayan tıkayıcı uyku apnesi üzerindeki rolü

Year 2016, Volume: 26 Issue: 4, 219 - 224, 10.09.2016

Abstract

Amaç: Bu çalışmada burun patolojileri ve pozisyonel PP tıkayıcı uyku apnesi TUA veya pozisyonel olmayan PO TUA arasındaki ilişki incelendi.Hastalar ve Yöntemler: Burun tıkanıklığı olan toplam 44 erkek TUA hastası ort. yaş 48.0±6.8 yıl; dağılım 31-60 yıl burun tıkanıklığı skorları, genel apne hipopne indeksi AHİ ve sırtüstü ve sırtüstü olmayan pozisyonlarda AHİ, gündüz uykululuk skorları ve vücut kütle indeksi VKİ açısından retrospektif olarak değerlendirildi. Hastalar PP grubu ve PO grubu olmak üzere iki eşit gruba ayrıldı. Çıktı parametreleri horlama şiddeti indeksi, klinik burun tıkanıklığı skoru, septum deviasyonu skoru, konka hipertrofisi skoru ve alerjik rinit AR skoru idi. Bu parametreler TUA tipi ile ilişkiliydi.Bulgular: Apne hipopne indeksi PP grubunda PO grubundan anlamlı olarak daha düşüktü p

References

  • Oksenberg A, Khamaysi I, Silverberg DS, Tarasiuk A. Association of body position with severity of apneic events in patients with severe nonpositional obstructive sleep apnea. Chest 2000;118:1018-24.
  • Ozeke O, Erturk O, Gungor M, Hızel SB, Aydın D, Celenk MK, et al. Influence of the right- versus left-sided sleeping position on the apnea-hypopnea index in patients with sleep apnea. Sleep Breath 2012;16:617-20.
  • Chung JW, Enciso R, Levendowski DJ, Westbrook PR, Clark GT. Patients with positional versus nonpositional obstructive sleep apnea: a retrospective study of risk factors associated with apnea-hypopnea severity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:605-10.
  • Oksenberg A, Silverberg DS. The effect of body posture on sleep-related breathing disorders: facts and therapeutic implications. Sleep Med Rev 1998;2:139-62.
  • Rundcrantz H. Postural variations of nasal patency. Acta Otolaryngol 1969;68:435-43.
  • De Vito A, Berrettini S, Carabelli A, Sellari-Franceschini S, Bonanni E, Gori S, et al. The importance of nasal resistance in obstructive sleep apnea syndrome: a study with positional rhinomanometry. Sleep Breath 2001;5:3-11.
  • Patel AV, Hwang D, Masdeu MJ, Chen GM, Rapoport DM, Ayappa I. Predictors of response to a nasal expiratory resistor device and its potential mechanisms of action for treatment of obstructive sleep apnea. J Clin Sleep Med 2011;7:13-22.
  • Penzel T, Möller M, Becker HF, Knaack L, Peter JH. Effect of sleep position and sleep stage on the collapsibility of the upper airways in patients with sleep apnea. Sleep 2001;24:90-5.
  • Ong JS, Touyz G, Tanner S, Hillman DR, Eastwood PR, Walsh JH. Variability of human upper airway collapsibility during sleep and the influence of body posture and sleep stage. J Sleep Res 2011;20:533-7.
  • Pracharktam N, Hans MG, Strohl KP, Redline S. Upright and supine cephalometric evaluation of obstructive sleep apnea syndrome and snoring subjects. Angle Orthod 1994;64:63-73.
  • Ono T, Lowe AA, Ferguson KA, Fleetham JA. Associations among upper airway structure, body position, and obesity in skeletal Class I male patients with obstructive sleep apnea. Am J Orthod Dentofacial Orthop 1996;109:625-34.
  • Virkkula P, Maasilta P, Hytönen M, Salmi T, Malmberg H. Nasal obstruction and sleep-disordered breathing: the effect of supine body position on nasal measurements in snorers. Acta Otolaryngol 2003;123:648-54.
  • Izci B, Ardic S, Firat H, Sahin A, Altinors M, Karacan I. Reliability and validity studies of the Turkish version of the Epworth Sleepiness Scale. Sleep Breath 2008;12:161-8.
  • Rhee CS, Kim DY, Won TB, Lee HJ, Park SW, Kwon TY, et al. Changes of nasal function after temperature- controlled radiofrequency tissue volume reduction for the turbinate. Laryngoscope 2001;111:153-8.
  • Sapçi T, Sahin B, Karavus A, Akbulut UG. Comparison of the effects of radiofrequency tissue ablation, CO2 laser ablation, and partial turbinectomy applications on nasal mucociliary functions. Laryngoscope 2003;113:514-9.
  • Yilmaz M, Kemaloğlu YK, Baysal E, Tutar H. Radiofrequency for inferior turbinate hypertrophy: could its long-term effect be predicted with a preoperative topical vasoconstrictor drop test? Am J Rhinol 2006;20:32-5.
  • Schwartz AR, Patil SP, Laffan AM, Polotsky V, Schneider H, Smith PL. Obesity and obstructive sleep apnea: pathogenic mechanisms and therapeutic approaches. Proc Am Thorac Soc 2008;5:185-92.
  • Ugur KS, Ark N, Kurtaran H, Kizilbulut G, Cakir B, Ozol D, et al. Subcutaneous fat tissue thickness of the anterior neck and umbilicus in patients with obstructive sleep apnea. Otolaryngol Head Neck Surg 2011;145:505-10.
  • McNicholas WT, Tarlo S, Cole P, Zamel N, Rutherford R, Griffin D, et al. Obstructive apneas during sleep in patients with seasonal allergic rhinitis. Am Rev Respir Dis 1982;126:625-8.
  • Young T, Finn L, Palta M. Chronic nasal congestion at night is a risk factor for snoring in a population-based cohort study. Arch Intern Med 2001;161:1514-9.
  • Ferguson BJ. Influences of allergic rhinitis on sleep. Otolaryngol Head Neck Surg 2004;130:617-29.
  • Kalpaklioğlu AF, Kavut AB, Ekici M. Allergic and nonallergic rhinitis: the threat for obstructive sleep apnea. Ann Allergy Asthma Immunol 2009;103:20-5.
  • Meng J, Xuan J, Qiao X, Li X, Liu S, Lukat KF, et al. Assessment of sleep impairment in persistent allergic rhinitis patients using polysomnography. Int Arch Allergy Immunol 2011;155:57-62.
  • Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008;63:8-160.
There are 24 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Raşit Cevizci This is me

Yusuf Kemal Kemaloğlu This is me

Metin Yılmaz This is me

Mehmet Düzlü This is me

Recep Karamert This is me

Publication Date September 10, 2016
Published in Issue Year 2016 Volume: 26 Issue: 4

Cite

APA Cevizci, R., Kemaloğlu, Y. K., Yılmaz, M., Düzlü, M., et al. (2016). Role of nasal problems on positional and nonpositional obstructive sleep apnea. The Turkish Journal of Ear Nose and Throat, 26(4), 219-224.
AMA Cevizci R, Kemaloğlu YK, Yılmaz M, Düzlü M, Karamert R. Role of nasal problems on positional and nonpositional obstructive sleep apnea. Tr-ENT. September 2016;26(4):219-224.
Chicago Cevizci, Raşit, Yusuf Kemal Kemaloğlu, Metin Yılmaz, Mehmet Düzlü, and Recep Karamert. “Role of Nasal Problems on Positional and Nonpositional Obstructive Sleep Apnea”. The Turkish Journal of Ear Nose and Throat 26, no. 4 (September 2016): 219-24.
EndNote Cevizci R, Kemaloğlu YK, Yılmaz M, Düzlü M, Karamert R (September 1, 2016) Role of nasal problems on positional and nonpositional obstructive sleep apnea. The Turkish Journal of Ear Nose and Throat 26 4 219–224.
IEEE R. Cevizci, Y. K. Kemaloğlu, M. Yılmaz, M. Düzlü, and R. Karamert, “Role of nasal problems on positional and nonpositional obstructive sleep apnea”, Tr-ENT, vol. 26, no. 4, pp. 219–224, 2016.
ISNAD Cevizci, Raşit et al. “Role of Nasal Problems on Positional and Nonpositional Obstructive Sleep Apnea”. The Turkish Journal of Ear Nose and Throat 26/4 (September 2016), 219-224.
JAMA Cevizci R, Kemaloğlu YK, Yılmaz M, Düzlü M, Karamert R. Role of nasal problems on positional and nonpositional obstructive sleep apnea. Tr-ENT. 2016;26:219–224.
MLA Cevizci, Raşit et al. “Role of Nasal Problems on Positional and Nonpositional Obstructive Sleep Apnea”. The Turkish Journal of Ear Nose and Throat, vol. 26, no. 4, 2016, pp. 219-24.
Vancouver Cevizci R, Kemaloğlu YK, Yılmaz M, Düzlü M, Karamert R. Role of nasal problems on positional and nonpositional obstructive sleep apnea. Tr-ENT. 2016;26(4):219-24.