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Wegener granulomatosis in parotid fistula and bilateral nasal mass

Year 2017, Volume: 27 Issue: 1, 51 - 55, 05.03.2017

Abstract

Wegener granulomatosis WG is a vasculitis which otorhinolaryngological involvement is very frequent, but is often diagnosed in the late stage and makes the diagnosis complicated in limited cases without systemic involvement. As it can mortally progress in case of late diagnosis, it is a condition which should be always considered in the differential diagnosis by the ear-nose-and-throat specialists. Herein, we report a limited WG case which manifests itself with parotid gland and nasal involvement and was diagnosed based on the clinical and pathological findings.

References

  • Srouji IA, Andrews P, Edwards C, Lund VJ. Patterns of presentation and diagnosis of patients with Wegener’s granulomatosis: ENT aspects. J Laryngol Otol 2007;121:653-8.
  • Kallenberg CG. Antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis. Curr Opin Rheumatol 2007;19:17-24.
  • Eriksson P, Jacobsson L, Lindell A, Nilsson JA, Skogh T. Improved outcome in Wegener’s granulomatosis and microscopic polyangiitis? A retrospective analysis of 95 cases in two cohorts. J Intern Med 2009;265:496-506.
  • Renaudineau Y, Le Meur Y. Renal involvement in Wegener’s granulomatosis. Clin Rev Allergy Immunol 2008;35:22-9.
  • Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis. Arthritis Rheum 1990;33:1101-7.
  • Kerr GS, Fleisher TA, Hallahan CW, Leavitt RY, Fauci AS, Hoffman GS. Limited prognostic value of changes in antineutrophil cytoplasmic antibody titer in patients with Wegener’s granulomatosis. Arthritis Rheum 1993;36:365-71.
  • Gubbels SP, Barkhuizen A, Hwang PH. Head and neck manifestations of Wegener’s granulomatosis. Otolaryngol Clin North Am 2003;36:685-705.
  • Gu X, Gu J. Analysis of nasal clinical manifestations and treatment of granulomatosis with polyangiitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2014;28:1577-8. [Abstract]
  • Rimmer J, Andrews P, Lund VJ. Eosinophilic angiocentric fibrosis of the nose and sinuses. J Laryngol Otol 2014;128:1071-7.
  • Yavuz M, Karabulut Y, Güllülü M, Ersoy A, Dalkılıç E, Filiz G, Dilek K, Yurtkuran M: Farklı seyirli dört Wegener Granülomatoz Olgusu. Turk Neph Dial Transpl 1999;8:40-2.
  • Chegar BE, Kelley RT. Wegener’s granulomatosis presenting as unilateral parotid enlargement. Laryngoscope 2004;114:1730-3.
  • Jayne D for the European Vasculitis Study Group (EUVAS). Uptodate on the European Vasculitis Study Group trials Curr. Opin Rheumatol 2001;13:541-9.
  • Takagi D, Nakamaru Y, Maguchi S, Furuta Y, Fukuda S. Otologic manifestations of Wegener’s granulomatosis. Laryngoscope 2002;112:1684-90.
  • Fenton JE, O’Sullivan TJ. The otological manifestations of Wegener’s granulomatosis. J Laryngol Otol 1994;108:144-6.
  • Moussa AE, Abou-Elhmd KA. Wegener’s granulomatosis presenting as mastoiditis. Ann Otol Rhinol Laryngol 1998;107:560-3.
  • Banerjee A, Armas JM, Dempster JH. Wegener’s granulomatosis: diagnostic dilemma. J Laryngol Otol 2001;115:46-7.

Parotis fistülünde ve iki taraflı nazal kitlede Wegener granülomatozu

Year 2017, Volume: 27 Issue: 1, 51 - 55, 05.03.2017

Abstract

Wegener granülomatozu WG , otorinolarengolojik tutulumun çok sık olduğu, ancak sistemik tutulumunun eşlik etmediği sınırlı olgularda, tanı konulmasında sıkıntı yaşanan ve genellikle geç tanı konulan bir vaskülittir. Geç tanı konulduğunda ise mortal seyredebileceğinden, Kulak Burun Boğaz hekimlerinin her zaman ayırıcı tanıda göz önünde bulundurması gereken bir hastalıktır. Bu yazıda, parotis bezi ve nazal tutulum ile kendini gösteren ve klinik ve patolojik bulgular ile tanısı konulmuş sınırlı bir WG olgusu sunuldu

References

  • Srouji IA, Andrews P, Edwards C, Lund VJ. Patterns of presentation and diagnosis of patients with Wegener’s granulomatosis: ENT aspects. J Laryngol Otol 2007;121:653-8.
  • Kallenberg CG. Antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis. Curr Opin Rheumatol 2007;19:17-24.
  • Eriksson P, Jacobsson L, Lindell A, Nilsson JA, Skogh T. Improved outcome in Wegener’s granulomatosis and microscopic polyangiitis? A retrospective analysis of 95 cases in two cohorts. J Intern Med 2009;265:496-506.
  • Renaudineau Y, Le Meur Y. Renal involvement in Wegener’s granulomatosis. Clin Rev Allergy Immunol 2008;35:22-9.
  • Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis. Arthritis Rheum 1990;33:1101-7.
  • Kerr GS, Fleisher TA, Hallahan CW, Leavitt RY, Fauci AS, Hoffman GS. Limited prognostic value of changes in antineutrophil cytoplasmic antibody titer in patients with Wegener’s granulomatosis. Arthritis Rheum 1993;36:365-71.
  • Gubbels SP, Barkhuizen A, Hwang PH. Head and neck manifestations of Wegener’s granulomatosis. Otolaryngol Clin North Am 2003;36:685-705.
  • Gu X, Gu J. Analysis of nasal clinical manifestations and treatment of granulomatosis with polyangiitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2014;28:1577-8. [Abstract]
  • Rimmer J, Andrews P, Lund VJ. Eosinophilic angiocentric fibrosis of the nose and sinuses. J Laryngol Otol 2014;128:1071-7.
  • Yavuz M, Karabulut Y, Güllülü M, Ersoy A, Dalkılıç E, Filiz G, Dilek K, Yurtkuran M: Farklı seyirli dört Wegener Granülomatoz Olgusu. Turk Neph Dial Transpl 1999;8:40-2.
  • Chegar BE, Kelley RT. Wegener’s granulomatosis presenting as unilateral parotid enlargement. Laryngoscope 2004;114:1730-3.
  • Jayne D for the European Vasculitis Study Group (EUVAS). Uptodate on the European Vasculitis Study Group trials Curr. Opin Rheumatol 2001;13:541-9.
  • Takagi D, Nakamaru Y, Maguchi S, Furuta Y, Fukuda S. Otologic manifestations of Wegener’s granulomatosis. Laryngoscope 2002;112:1684-90.
  • Fenton JE, O’Sullivan TJ. The otological manifestations of Wegener’s granulomatosis. J Laryngol Otol 1994;108:144-6.
  • Moussa AE, Abou-Elhmd KA. Wegener’s granulomatosis presenting as mastoiditis. Ann Otol Rhinol Laryngol 1998;107:560-3.
  • Banerjee A, Armas JM, Dempster JH. Wegener’s granulomatosis: diagnostic dilemma. J Laryngol Otol 2001;115:46-7.
There are 16 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Emine Demir This is me

Görkem Atsal This is me

Tolgahan Çatlı This is me

Aysel Hasanova This is me

Ayşe Yağcı This is me

Levent Olgun This is me

Publication Date March 5, 2017
Published in Issue Year 2017 Volume: 27 Issue: 1

Cite

APA Demir, E., Atsal, G., Çatlı, T., Hasanova, A., et al. (2017). Wegener granulomatosis in parotid fistula and bilateral nasal mass. The Turkish Journal of Ear Nose and Throat, 27(1), 51-55.
AMA Demir E, Atsal G, Çatlı T, Hasanova A, Yağcı A, Olgun L. Wegener granulomatosis in parotid fistula and bilateral nasal mass. Tr-ENT. March 2017;27(1):51-55.
Chicago Demir, Emine, Görkem Atsal, Tolgahan Çatlı, Aysel Hasanova, Ayşe Yağcı, and Levent Olgun. “Wegener Granulomatosis in Parotid Fistula and Bilateral Nasal Mass”. The Turkish Journal of Ear Nose and Throat 27, no. 1 (March 2017): 51-55.
EndNote Demir E, Atsal G, Çatlı T, Hasanova A, Yağcı A, Olgun L (March 1, 2017) Wegener granulomatosis in parotid fistula and bilateral nasal mass. The Turkish Journal of Ear Nose and Throat 27 1 51–55.
IEEE E. Demir, G. Atsal, T. Çatlı, A. Hasanova, A. Yağcı, and L. Olgun, “Wegener granulomatosis in parotid fistula and bilateral nasal mass”, Tr-ENT, vol. 27, no. 1, pp. 51–55, 2017.
ISNAD Demir, Emine et al. “Wegener Granulomatosis in Parotid Fistula and Bilateral Nasal Mass”. The Turkish Journal of Ear Nose and Throat 27/1 (March 2017), 51-55.
JAMA Demir E, Atsal G, Çatlı T, Hasanova A, Yağcı A, Olgun L. Wegener granulomatosis in parotid fistula and bilateral nasal mass. Tr-ENT. 2017;27:51–55.
MLA Demir, Emine et al. “Wegener Granulomatosis in Parotid Fistula and Bilateral Nasal Mass”. The Turkish Journal of Ear Nose and Throat, vol. 27, no. 1, 2017, pp. 51-55.
Vancouver Demir E, Atsal G, Çatlı T, Hasanova A, Yağcı A, Olgun L. Wegener granulomatosis in parotid fistula and bilateral nasal mass. Tr-ENT. 2017;27(1):51-5.