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An aggressive papillary tumor of middle ear: A case report

Year 2019, Volume: 29 Issue: 3, 146 - 149, 25.09.2019

Abstract

Aggressive papillary tumors of the middle ear constitute a small percent of adenomatous middle ear tumors. Patients usually present with long-lasting tinnitus, hearing loss, and vertigo and occasionally facial paralysis. Computed tomography findings predominantly suggest bone invasion. Thus, it is commonly misdiagnosed with chronic otitis media with a cholesteatoma. A 72-year-old man presented with chronic ear pain and ear drainage. The patient had a 63 decibels dB mixed-type hearing loss and a mass lesion at the temporal bone high resolution computed tomography. Explorative tympanotomy revealed a tumor with thick mucoid secretion and no bone erosion, for which an incisional biopsy revealed an adenoma. Radical modified mastoidectomy was performed and the definite pathology result was compatible with an aggressive papillary tumor. The patient was free of disease at six months of follow-up.

References

  • Eby TL, Makek MS, Fisch U. Adenomas of the temporal bone. Ann Otol Rhinol Laryngol 1988;97:605-12.
  • el-Naggar AK, Pflatz M, Ordóñez NG, Batsakis JG. Tumors of the middle ear and endolymphatic sac. Pathol Annu 1994;29:199-231.
  • Gaffey MJ, Mills SE, Fechner RE, Intemann SR, Wick MR. Aggressive papillary middle-ear tumor. A clinicopathologic entity distinct from middle-ear adenoma. Am J Surg Pathol 1988;12:790-7.
  • Heffner DK. Low-grade adenocarcinoma of probable endolymphatic sac origin A clinicopathologic study of 20 cases. Cancer 1989;64:2292-302.
  • Michaels L, Beale T, Sandison A, Soucek S. Endolymphatic sac tumour. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005. p. 355-6.
  • Schipper J, Maier W, Rosahl SK, van Velthoven V, Berlis A, Boedeker CC, et al. Endolymphatic sac tumours: surgical management. J Otolaryngol 2006;35:387-94.
  • Chetty R, Kennedy M, Ezzat S, Asa SL. Pancreatic endocrine pathology in von Hippel-Lindau disease: an expanding spectrum of lesions. Endocr Pathol 2004;15:141-8.
  • Friedrich CA. Von Hippel-Lindau syndrome. A pleomorphic condition. Cancer 1999;86:2478-82.
  • Thompson LD. Update From the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumours of the Ear. Head Neck Pathol 2017;11:78-87.
  • Kawabata S, Hollander MC, Munasinghe JP, Brinster LR, Mercado-Matos JR, Li J, et al. Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone. Oncotarget 2015;6:11357-68.
  • Pollak A, Böhmer A, Spycher M, Fisch U. Are papillary adenomas endolymphatic sac tumors? Ann Otol Rhinol Laryngol 1995;104:613-9.
  • Elhefnawy NG. Aggressive low grade middle ear adenocarcinoma with multiple recurrences: a case report. Diagn Pathol 2011;6:62.
  • Arava S, Soumya RM, Chitragar S, Safaya R, Chandrashekhar SH, Thakar A. Papillary endolymphatic sac tumor: a case report. Case Rep Otolaryngol 2012;2012:163851.

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Year 2019, Volume: 29 Issue: 3, 146 - 149, 25.09.2019

Abstract

References

  • Eby TL, Makek MS, Fisch U. Adenomas of the temporal bone. Ann Otol Rhinol Laryngol 1988;97:605-12.
  • el-Naggar AK, Pflatz M, Ordóñez NG, Batsakis JG. Tumors of the middle ear and endolymphatic sac. Pathol Annu 1994;29:199-231.
  • Gaffey MJ, Mills SE, Fechner RE, Intemann SR, Wick MR. Aggressive papillary middle-ear tumor. A clinicopathologic entity distinct from middle-ear adenoma. Am J Surg Pathol 1988;12:790-7.
  • Heffner DK. Low-grade adenocarcinoma of probable endolymphatic sac origin A clinicopathologic study of 20 cases. Cancer 1989;64:2292-302.
  • Michaels L, Beale T, Sandison A, Soucek S. Endolymphatic sac tumour. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005. p. 355-6.
  • Schipper J, Maier W, Rosahl SK, van Velthoven V, Berlis A, Boedeker CC, et al. Endolymphatic sac tumours: surgical management. J Otolaryngol 2006;35:387-94.
  • Chetty R, Kennedy M, Ezzat S, Asa SL. Pancreatic endocrine pathology in von Hippel-Lindau disease: an expanding spectrum of lesions. Endocr Pathol 2004;15:141-8.
  • Friedrich CA. Von Hippel-Lindau syndrome. A pleomorphic condition. Cancer 1999;86:2478-82.
  • Thompson LD. Update From the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Tumours of the Ear. Head Neck Pathol 2017;11:78-87.
  • Kawabata S, Hollander MC, Munasinghe JP, Brinster LR, Mercado-Matos JR, Li J, et al. Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone. Oncotarget 2015;6:11357-68.
  • Pollak A, Böhmer A, Spycher M, Fisch U. Are papillary adenomas endolymphatic sac tumors? Ann Otol Rhinol Laryngol 1995;104:613-9.
  • Elhefnawy NG. Aggressive low grade middle ear adenocarcinoma with multiple recurrences: a case report. Diagn Pathol 2011;6:62.
  • Arava S, Soumya RM, Chitragar S, Safaya R, Chandrashekhar SH, Thakar A. Papillary endolymphatic sac tumor: a case report. Case Rep Otolaryngol 2012;2012:163851.
There are 13 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Berkay Çaytemel This is me

Can Doruk This is me

Çağla Karaoğlan This is me

Beldan Polat This is me

Publication Date September 25, 2019
Published in Issue Year 2019 Volume: 29 Issue: 3

Cite

APA Çaytemel, B., Doruk, C., Karaoğlan, Ç., Polat, B. (2019). An aggressive papillary tumor of middle ear: A case report. The Turkish Journal of Ear Nose and Throat, 29(3), 146-149.
AMA Çaytemel B, Doruk C, Karaoğlan Ç, Polat B. An aggressive papillary tumor of middle ear: A case report. Tr-ENT. September 2019;29(3):146-149.
Chicago Çaytemel, Berkay, Can Doruk, Çağla Karaoğlan, and Beldan Polat. “An Aggressive Papillary Tumor of Middle Ear: A Case Report”. The Turkish Journal of Ear Nose and Throat 29, no. 3 (September 2019): 146-49.
EndNote Çaytemel B, Doruk C, Karaoğlan Ç, Polat B (September 1, 2019) An aggressive papillary tumor of middle ear: A case report. The Turkish Journal of Ear Nose and Throat 29 3 146–149.
IEEE B. Çaytemel, C. Doruk, Ç. Karaoğlan, and B. Polat, “An aggressive papillary tumor of middle ear: A case report”, Tr-ENT, vol. 29, no. 3, pp. 146–149, 2019.
ISNAD Çaytemel, Berkay et al. “An Aggressive Papillary Tumor of Middle Ear: A Case Report”. The Turkish Journal of Ear Nose and Throat 29/3 (September 2019), 146-149.
JAMA Çaytemel B, Doruk C, Karaoğlan Ç, Polat B. An aggressive papillary tumor of middle ear: A case report. Tr-ENT. 2019;29:146–149.
MLA Çaytemel, Berkay et al. “An Aggressive Papillary Tumor of Middle Ear: A Case Report”. The Turkish Journal of Ear Nose and Throat, vol. 29, no. 3, 2019, pp. 146-9.
Vancouver Çaytemel B, Doruk C, Karaoğlan Ç, Polat B. An aggressive papillary tumor of middle ear: A case report. Tr-ENT. 2019;29(3):146-9.