Hyperbaric oxygen therapy: The last remedy for sudden sensorineural hearing loss?

Year 2020, Volume: 30 Issue: 1, 8 - 13, 20.03.2020

Yüksel Olgun Fatih Yunus Emre Aslı Çakır Çetin Günay Kırkım Hülya Ellidokuz Enis Alpin Güneri

Abstract

Objectives: This study aims to evaluate hyperbaric oxygen HBO therapy as a salvage treatment option for sudden sensorineural hearing loss SSNHL and analyze factors influencing treatment outcomes. Patients and Methods: Charts of 27 patients 20 males, 7 females; mean age 50.8 years; range, 30 to 74 years who received HBO therapy as salvage treatment were retrospectively evaluated between January 2007 and December 2017. Patients’ demographics, time between onset of SSNHL to the initiation of steroid and HBO treatments, audiogram curves, tinnitus, vestibular symptoms, and pure tone audiometry results before and after steroid and HBO therapies were evaluated. Siegle’s criteria were used to evaluate treatment outcomes. Results: According to Siegle’s criteria, while seven patients had slight improvement, partial improvement was seen in two patients. With HBO therapy, a statistically significant improvement was seen at 250, 500, and 8000 Hz frequencies. Diabetes mellitus and patients’ age were related with treatment outcomes. Conclusion: Hyperbaric oxygen therapy may be beneficial as a salvage treatment option in some patients. Better results may be expected particularly in young and non-diabetic patients.

Keywords

Hearing loss, hyperbaric oxygen, sensorineural

References

• Stachler RJ, Chandrasekhar SS, Archer SM, Rosenfeld RM, Schwartz SR, Barrs DM, et al Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg 2012;146:S1-35.
• Edizer DT, Çelebi Ö, Hamit B, Baki A, Yiğit Ö. Recovery of Idiopathic Sudden Sensorineural Hearing Loss. J Int Adv Otol 2015;11:122-6.
• Ajduk J, Ries M, Trotic R, Marinac I, Vlatka K, Bedekovic V. Hyperbaric oxygen therapy as salvage therapy for sudden sensorineural hearing loss. J Int Adv Otol 2017;13:61-4.
• Yang CH, Wu RW, Hwang CF. Comparison of intratympanic steroid injection, hyperbaric oxygen and combination therapy in refractory sudden sensorineural hearing loss. Otol Neurotol 2013;34:1411-6.
• Siegel LG. The treatment of idiopathic sudden sensorineural hearing loss. Otolaryngol Clin North Am 1975;8:467-73.
• Muzzi E, Zennaro B, Visentin R, Soldano F, Sacilotto C. Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: review of rationale and preliminary report. J Laryngol Otol 2010;124:e2.
• Aslan I, Oysu C, Veyseller B, Baserer N. Does the addition of hyperbaric oxygen therapy to the conventional treatment modalities influence the outcome of sudden deafness? Otolaryngol Head Neck Surg 2002;126:121-6.
• Conlin AE, Parnes LS. Treatment of sudden sensorineural hearing loss: II. A Meta-analysis. Arch Otolaryngol Head Neck Surg 2007;133:582-6.
• Sun H, Qiu X, Hu J, Ma Z. Comparison of intratympanic dexamethasone therapy and hyperbaric oxygen therapy for the salvage treatment of refractory high- frequency sudden sensorineural hearing loss. Am J Otolaryngol 2018;39:531-5.
• Tsounis M, Psillas G, Tsalighopoulos M, Vital V, Maroudias N, Markou K. Systemic, intratympanic and combined administration of steroids for sudden hearing loss. A prospective randomized multicenter trial. Eur Arch Otorhinolaryngol 2018;275:103-10.
• Ocak E, Beton S, Kesici GG, Aktürk T. Can Intratympanic Steroid Be Initial Therapy for Sudden Sensorineural Hearing Loss? Turk Arch Otolaryngol 2014;52:12-6.
• Suzuki H, Wakasugi T, Kitamura T, Koizumi H, Do BH, Ohbuchi T. Comparison of 2 and 4 Intratympanic Steroid Injections in the Treatment of Idiopathic Sudden Sensorineural Hearing Loss. Ann Otol Rhinol Laryngol 2018;127:235-40.
• Horn CE, Himel HN, Selesnick SH. Hyperbaric oxygen therapy for sudden sensorineural hearing loss: a prospective trial of patients failing steroid and antiviral treatment. Otol Neurotol 2005;26:882-9.
• Pezzoli M, Magnano M, Maffi L, Pezzoli L, Marcato P, Orione M, Cupi D, Bongioannini G. Hyperbaric oxygen therapy as salvage treatment for sudden sensorineural hearing loss: a prospective controlled study. Eur Arch Otorhinolaryngol 2015;272:1659-66.
• Alimoglu Y, Inci E. Is hyperbaric oxygen therapy a salvage treatment option for sudden sensorineural hearing loss? J Laryngol Otol 2016;130:943-7.
• Moon IS, Lee JD, Kim J, Hong SJ, Lee WS. Intratympanic dexamethasone is an effective method as a salvage treatment in refractory sudden hearing loss. Otol Neurotol 2011;32:1432-6.
• Lee JB, Choi SJ, Park K, Park HY, Choo OS, Choung YH. The efficiency of intratympanic dexamethasone injection as a sequential treatment after initial systemic steroid therapy for sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2011;268:833-9.
• Weng SF, Chen YS, Hsu CJ, Tseng FY. Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope 2005;115:1676-80.
• Ceylan A, Celenk F, Kemaloğlu YK, Bayazit YA, Göksu N, Ozbilen S. Impact of prognostic factors on recovery from sudden hearing loss. J Laryngol Otol 2007;121:1035-40.
• Wen YH, Chen PR, Wu HP. Prognostic factors of profound idiopathic sudden sensorineural hearing loss. Eur Arch Otorhinolaryngol 2014;271:1423-9.
• Topuz E, Yigit O, Cinar U, Seven H. Should hyperbaric oxygen be added to treatment in idiopathic sudden sensorineural hearing loss? Eur Arch Otorhinolaryngol 2004;261:393-6.
• Chao TK, Chen TH. Distortion product otoacoustic emissions as a prognostic factor for idiopathic sudden sensorineural hearing loss. Audiol Neurootol 2006;11:331-8.
• Mamak A, Yilmaz S, Cansiz H, Inci E, Güçlü E, Dereköylü L. A study of prognostic factors in sudden hearing loss. Ear Nose Throat J 2005;84:641-4.
• Cvorović L, Deric D, Probst R, Hegemann S. Prognostic model for predicting hearing recovery in idiopathic sudden sensorineural hearing loss. Otol Neurotol 2008;29:464-9.
• Salvago P, Rizzo S, Bianco A, Martines F. Sudden sensorineural hearing loss: is there a relationship between routine haematological parameters and audiogram shapes? Int J Audiol 2017;56:148-53.