SIKLOHEKZANDIKARBOKSILLI ASIDIN SENTEZI VE pH ETKISI İLE SU VE ORGANIK FAZLARDAN EKSTRAKSIYONUNUN İNCELENMESI

Year 2017, Volume: 18 Issue: 1, 1 - 7, 10.03.2017

Nilgün Becenen , Gühergül Uluçam , Özlen Altun

https://doi.org/10.23902/trkjnat.284521

Abstract

Bu
çalışmada, reflux şartlarında demir siklohekzandikarboksilli asit
sentezlenmiştir. Kompleksin yapısı fizikokimyasal ve spektroskopik metodlarla
karakterize edilmiştir. Daha sonra reaksiyon sırasında pH’ın su ve organik
fazlardaki paylaşma sabitleri () ve ekstraksiyon yüzdelerine (%E) etkisi
ekstraksiyon metodu ile incelenmiştir. Deney sonucunda, su fazındaki Fe2+
iyonlarının çoğu pH=7.5’ta organik faza geçmiştir. Bu pH’tan sonra ekstraksiyon
yüzdesi su fazından organik faza geçiş yüzünden azalmıştır. Demir siklohekzandikarboksilli
asit eter, petrol eteri, benzol ve karbon tetra klorür ile sulu çözeltilerinden
ekstre edilmiş, ilave olarak kompleksin mikrobiyal aktiviteleri çalışılmıştır.
Aktivite sonuçları, demir siklohekzandikarboksilli asitin önemli antibakteriyal
ve antifungal aktiviteye sahip olduğunu göstermiştir.

Keywords

Fe (II), siklohekzandikarboksilli asit, sentez, ekstraksiyon

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF IRON CYCLOHEXANEDICARBOXYLIC ACID AND EXAMINATION OF pH EFFECT ON EXTRACTION IN WATER AND ORGANIC PHASES

Abstract

In this study, iron cyclohexanedicarboxylic acid was
synthesized under refluxing conditions. The structural characterization of the
complex was performed by using physico-chemical and spectroscopic methods. The
effect of pH on division constant (µ) and extraction percentages (% E) in water and
organic phase was
investigated with the extraction method. At the end of the experiment,
most of the Fe²⁺ ions in the water phase at pH=7.5 passed into the
organic phase. Above this pH, the extraction percentage decreased because of
the transition from water phase to organic phase. Iron cyclohexanedicarboxylic acid
was extracted with ether, petroleum ether, benzole and carbon tetrachloride from aqueous solution and microbial activities
of the complex were studied. The activity data showed that iron cyclohexanedicarboxylic
acid has an important antibacterial and antifungal activities.

Keywords

Fe (II), cyclohexanedicarboxylic acid, synthesis, extraction

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