Fatigue in long-COVID; frequency, severity and impact on quality of life

Abstract

Objective: The aim of our study was to investigate the frequency, severity, and impact on quality of life related to fatigue during the prolonged period of COVID-19. Methods: The cross-sectional study consists of data of 266 participants aged 18 and above, all with confirmed diagnoses of COVID-19. Participants' fatigue severity was assessed using the Modified Fa-tigue Impact Scale (mFIS) and their quality of life using the Nothingham Health Profile (NHP). Results: Of the 266 participants, 60 reported no fatigue complaints, 132 experienced fatigue during the acute illness that subsequently resolved and 74 (33.6%) noted persistent fatigue beyond the acute ill-ness period. Participants with fatigue exhibited significantly lower quality of life scores compared to those without, particularly affecting the NHP Pain, Physical Activity, and Energy subscales. The NHP scores positively correlate with mFIS scores. Conclusion: This study revealed that fatigue, which continues during the long-COVID period, impairs the quality of life in relation to its severity. Fatigue was notably associated with a reduced quality of life, particularly evident in the energy sub-dimension. These findings underscore the importance of add-ressing and managing post-COVID fatigue for improved overall well-being.

Keywords

• quality of life
• COVID-19
• Post-Acute COVID-19 Syndrome
• fatigue

Ethical Statement

The study (2011-KAEK-27/2022-2200013901) was conducted with the approval of the Clinical Research Ethics Committee of the Çanakkale Onsekiz Mart University (02.02.2022; 03-20).

Uzamış-COVID'de yorgunluk; sıklığı, şiddeti ve yaşam kalitesi üzerine etkisi

Abstract

Amaç: Çalışmada, uzamış COVID-19 döneminde yorgunluk sıklığını, şiddetini ve yaşam kalitesi üze-rindeki etkilerini araştırmak amaçlanmıştır. Yöntem: Kesitsel desendeki bu çalışma, 18 yaş ve üzeri, tamamı kesin COVID-19 teşhisi konmuş 266 katılımcının verilerini içermektedir. Katılımcıların yorgunluk şiddeti, Modifiye Yorgunluk Etki Ölçeği (mFIS) kullanılarak değerlendirilmiş ve yaşam kaliteleri Nothingham Sağlık Profili (NHP) ile ölçülmüş-tür. Bulgular: 266 katılımcıdan 60'ı herhangi bir yorgunluk şikayeti bildirmezken, 132'si akut hastalık sırasında yorgunluk yaşamış ve bu daha sonra çözülmüştür; 74'ü (%33.6) ise akut hastalık döneminin ötesinde süregelen bir yorgunluk belirtmiştir. Yorgunluğu olan katılımcılar, özellikle NHP Ağrı, Fizik-sel Aktivite ve Enerji alt ölçeklerini etkileyerek, yorgunluk yaşamayanlara göre anlamlı düşük yaşam kalitesi skorları sergilemiştir. NHP skorları, mFIS skorları ile pozitif korelasyon göstermiştir. Sonuç: Bu çalışma, uzamış COVID döneminde devam eden yorgunluğun, şiddetiyle orantılı olarak, özellikle enerji alt boyutunda azalmış yaşam kalitesi ile ilişkilendirildiğini ortaya koymuştur. Bu bul-gular, post-COVID yorgunluğunun ele alınması ve yönetilmesinin genel yaşam kalitesini iyileştirmek açısından önemini vurgular.

Keywords

• COVID-19
• yorgunluk
• yaşam kalitesi
• Post-Akut COVID-19 Sendromu

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